Structure of the angiotensin receptor revealed by serial femtosecond crystallography H Zhang, H Unal, C Gati, GW Han, W Liu, NA Zatsepin, D James, D Wang, ... Cell 161 (4), 833-844, 2015 | 259 | 2015 |
The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British Journal of Pharmacology 176, S21-S141, 2019 | 228 | 2019 |
International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin receptors: interpreters of pathophysiological angiotensinergic stimuli SS Karnik, H Unal, JR Kemp, KC Tirupula, S Eguchi, PML Vanderheyden, ... Pharmacological reviews 67 (4), 754-819, 2015 | 188* | 2015 |
Click chemistry on azidoproline: High‐affinity dual antagonist for HIV‐1 envelope glycoprotein gp120 HN Gopi, KC Tirupula, S Baxter, S Ajith, IM Chaiken ChemMedChem: Chemistry Enabling Drug Discovery 1 (1), 54-57, 2006 | 77 | 2006 |
Significance of angiotensin 1–7 coupling with MAS1 receptor and other GPCRs to the renin‐angiotensin system: IUPHAR Review 22 SS Karnik, KD Singh, K Tirupula, H Unal British journal of pharmacology 174 (9), 737-753, 2017 | 48 | 2017 |
pH‐dependent Interaction of Rhodopsin with Cyanidin‐3‐glucoside. 2. Functional Aspects† KC Tirupula, F Balem, N Yanamala, J Klein‐Seetharaman Photochemistry and photobiology 85 (2), 463-470, 2009 | 39 | 2009 |
Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors N Yanamala, KC Tirupula, J Klein-Seetharaman BMC bioinformatics 9 (S1), S16, 2008 | 35 | 2008 |
pH‐dependent Interaction of Rhodopsin with Cyanidin‐3‐glucoside. 1. Structural Aspects† N Yanamala, KC Tirupula, F Balem, J Klein‐Seetharaman Photochemistry and photobiology 85 (2), 454-462, 2009 | 33 | 2009 |
Long range effect of mutations on specific conformational changes in the extracellular loop 2 of angiotensin II type 1 receptor H Unal, R Jagannathan, A Bhatnagar, K Tirupula, R Desnoyer, SS Karnik Journal of Biological Chemistry 288 (1), 540-551, 2013 | 30 | 2013 |
Characterization of membrane protein non-native states. 1. Extent of unfolding and aggregation of rhodopsin in the presence of chemical denaturants A Dutta, KC Tirupula, U Alexiev, J Klein-Seetharaman Biochemistry 49 (30), 6317-6328, 2010 | 29 | 2010 |
Systematic prediction of human membrane receptor interactions Y Qi, HK Dhiman, N Bhola, I Budyak, S Kar, D Man, A Dutta, K Tirupula, ... Proteomics 9 (23), 5243-5255, 2009 | 29 | 2009 |
Atypical signaling and functional desensitization response of MAS receptor to peptide ligands KC Tirupula, R Desnoyer, RC Speth, SS Karnik PLoS One 9 (7), e103520, 2014 | 25 | 2014 |
G protein-coupled receptors directly bind filamin A with high affinity and promote filamin phosphorylation KC Tirupula, SS Ithychanda, ML Mohan, SV Naga Prasad, J Qin, ... Biochemistry 54 (44), 6673-6683, 2015 | 20 | 2015 |
Identification of motions in membrane proteins by elastic network models and their experimental validation B Isin, KC Tirupula, ZN Oltvai, J Klein-Seetharaman, I Bahar Membrane Protein Structure and Dynamics, 285-317, 2012 | 11 | 2012 |
A mechanism of global shape-dependent recognition and phosphorylation of filamin by protein kinase A SS Ithychanda, X Fang, ML Mohan, L Zhu, KC Tirupula, SVN Prasad, ... Journal of Biological Chemistry 290 (13), 8527-8538, 2015 | 10 | 2015 |
Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin J Mitchell, F Balem, K Tirupula, D Man, HK Dhiman, N Yanamala, ... PloS one 14 (5), e0214639, 2019 | 6 | 2019 |
MAS C-terminal tail interacting proteins identified by mass spectrometry-based proteomic approach KC Tirupula, D Zhang, A Osbourne, A Chatterjee, R Desnoyer, B Willard, ... PLoS One 10 (10), e0140872, 2015 | 6 | 2015 |
A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors S Moitra, KC Tirupula, J Klein-Seetharaman, CJ Langmead BMC biophysics 5 (1), 13, 2012 | 6 | 2012 |
Connective tissue growth factor dependent collagen gene expression induced by MAS agonist AR234960 in human cardiac fibroblasts A Chatterjee, J Barnard, C Moravec, R Desnoyer, K Tirupula, SS Karnik PloS one 12 (12), e0190217, 2017 | 3 | 2017 |
SARS-CoV-2 proteins (version 2020.2) in the IUPHAR/BPS Guide to Pharmacology Database SPH Alexander, JK Ball, T Tsoleridis IUPHAR/BPS Guide to Pharmacology CITE 2020 (2), 2020 | 2 | 2020 |