Kalyan C Tirupula
Kalyan C Tirupula
Sr. Research Scientist
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Structure of the angiotensin receptor revealed by serial femtosecond crystallography
H Zhang, H Unal, C Gati, GW Han, W Liu, NA Zatsepin, D James, D Wang, ...
Cell 161 (4), 833-844, 2015
The Concise Guide to PHARMACOLOGY 2019/20: G protein‐coupled receptors
SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ...
British Journal of Pharmacology 176, S21-S141, 2019
International Union of Basic and Clinical Pharmacology. XCIX. Angiotensin receptors: interpreters of pathophysiological angiotensinergic stimuli
SS Karnik, H Unal, JR Kemp, KC Tirupula, S Eguchi, PML Vanderheyden, ...
Pharmacological reviews 67 (4), 754-819, 2015
Click chemistry on azidoproline: High‐affinity dual antagonist for HIV‐1 envelope glycoprotein gp120
HN Gopi, KC Tirupula, S Baxter, S Ajith, IM Chaiken
ChemMedChem: Chemistry Enabling Drug Discovery 1 (1), 54-57, 2006
Significance of angiotensin 1–7 coupling with MAS1 receptor and other GPCRs to the renin‐angiotensin system: IUPHAR Review 22
SS Karnik, KD Singh, K Tirupula, H Unal
British journal of pharmacology 174 (9), 737-753, 2017
pH‐dependent Interaction of Rhodopsin with Cyanidin‐3‐glucoside. 2. Functional Aspects
KC Tirupula, F Balem, N Yanamala, J Klein‐Seetharaman
Photochemistry and photobiology 85 (2), 463-470, 2009
Preferential binding of allosteric modulators to active and inactive conformational states of metabotropic glutamate receptors
N Yanamala, KC Tirupula, J Klein-Seetharaman
BMC bioinformatics 9 (S1), S16, 2008
pH‐dependent Interaction of Rhodopsin with Cyanidin‐3‐glucoside. 1. Structural Aspects
N Yanamala, KC Tirupula, F Balem, J Klein‐Seetharaman
Photochemistry and photobiology 85 (2), 454-462, 2009
Long range effect of mutations on specific conformational changes in the extracellular loop 2 of angiotensin II type 1 receptor
H Unal, R Jagannathan, A Bhatnagar, K Tirupula, R Desnoyer, SS Karnik
Journal of Biological Chemistry 288 (1), 540-551, 2013
Characterization of membrane protein non-native states. 1. Extent of unfolding and aggregation of rhodopsin in the presence of chemical denaturants
A Dutta, KC Tirupula, U Alexiev, J Klein-Seetharaman
Biochemistry 49 (30), 6317-6328, 2010
Systematic prediction of human membrane receptor interactions
Y Qi, HK Dhiman, N Bhola, I Budyak, S Kar, D Man, A Dutta, K Tirupula, ...
Proteomics 9 (23), 5243-5255, 2009
Atypical signaling and functional desensitization response of MAS receptor to peptide ligands
KC Tirupula, R Desnoyer, RC Speth, SS Karnik
PLoS One 9 (7), e103520, 2014
G protein-coupled receptors directly bind filamin A with high affinity and promote filamin phosphorylation
KC Tirupula, SS Ithychanda, ML Mohan, SV Naga Prasad, J Qin, ...
Biochemistry 54 (44), 6673-6683, 2015
Identification of motions in membrane proteins by elastic network models and their experimental validation
B Isin, KC Tirupula, ZN Oltvai, J Klein-Seetharaman, I Bahar
Membrane Protein Structure and Dynamics, 285-317, 2012
A mechanism of global shape-dependent recognition and phosphorylation of filamin by protein kinase A
SS Ithychanda, X Fang, ML Mohan, L Zhu, KC Tirupula, SVN Prasad, ...
Journal of Biological Chemistry 290 (13), 8527-8538, 2015
Comparison of the molecular properties of retinitis pigmentosa P23H and N15S amino acid replacements in rhodopsin
J Mitchell, F Balem, K Tirupula, D Man, HK Dhiman, N Yanamala, ...
PloS one 14 (5), e0214639, 2019
MAS C-terminal tail interacting proteins identified by mass spectrometry-based proteomic approach
KC Tirupula, D Zhang, A Osbourne, A Chatterjee, R Desnoyer, B Willard, ...
PLoS One 10 (10), e0140872, 2015
A minimal ligand binding pocket within a network of correlated mutations identified by multiple sequence and structural analysis of G protein coupled receptors
S Moitra, KC Tirupula, J Klein-Seetharaman, CJ Langmead
BMC biophysics 5 (1), 13, 2012
Connective tissue growth factor dependent collagen gene expression induced by MAS agonist AR234960 in human cardiac fibroblasts
A Chatterjee, J Barnard, C Moravec, R Desnoyer, K Tirupula, SS Karnik
PloS one 12 (12), e0190217, 2017
SARS-CoV-2 proteins (version 2020.2) in the IUPHAR/BPS Guide to Pharmacology Database
SPH Alexander, JK Ball, T Tsoleridis
IUPHAR/BPS Guide to Pharmacology CITE 2020 (2), 2020
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