| On the convergent evolution of animal toxins conservation of a diad of functional residues in potassium channel-blocking toxins with unrelated structures M Dauplais, A Lecoq, J Song, J Cotton, N Jamin, B Gilquin, ... Journal of Biological Chemistry 272 (7), 4302-4309, 1997 | 429 | 1997 |
| ALS-causing mutations significantly perturb the self-assembly and interaction with nucleic acid of the intrinsically disordered prion-like domain of TDP-43 L Lim, Y Wei, Y Lu, J Song PLoS biology 14 (1), e1002338, 2016 | 202 | 2016 |
| Dissection Study on the Severe Acute Respiratory Syndrome 3C-like Protease Reveals the Critical Role of the Extra Domain in Dimerization of the Enzyme DEFINING THE EXTRA DOMAIN … J Shi, Z Wei, J Song Journal of Biological Chemistry 279 (23), 24765-24773, 2004 | 190 | 2004 |
| Mechanism for controlling the dimer-monomer switch and coupling dimerization to catalysis of the severe acute respiratory syndrome coronavirus 3C-like protease J Shi, J Sivaraman, J Song Journal of virology 82 (9), 4620-4629, 2008 | 154 | 2008 |
| The catalysis of the SARS 3C‐like protease is under extensive regulation by its extra domain J Shi, J Song The FEBS journal 273 (5), 1035-1045, 2006 | 148 | 2006 |
| TDP-43 N terminus encodes a novel ubiquitin-like fold and its unfolded form in equilibrium that can be shifted by binding to ssDNA H Qin, LZ Lim, Y Wei, J Song Proceedings of the National Academy of Sciences 111 (52), 18619-18624, 2014 | 141 | 2014 |
| A small molecule agonist of EphA2 receptor tyrosine kinase inhibits tumor cell migration in vitro and prostate cancer metastasis in vivo A Petty, E Myshkin, H Qin, H Guo, H Miao, GP Tochtrop, JT Hsieh, P Page, ... PloS one 7 (8), e42120, 2012 | 130 | 2012 |
| Structural characterization of the EphA4-Ephrin-B2 complex reveals new features enabling Eph-ephrin binding promiscuity H Qin, R Noberini, X Huan, J Shi, EB Pasquale, J Song Journal of Biological Chemistry 285 (1), 644-654, 2010 | 125 | 2010 |
| Structure of the Arabidopsis thaliana DCL4 DUF283 domain reveals a noncanonical double-stranded RNA-binding fold for protein–protein interaction H Qin, F Chen, X Huan, S Machida, J Song, YA Yuan Rna 16 (3), 474-481, 2010 | 116 | 2010 |
| Solution conformations of Zika NS2B-NS3pro and its inhibition by natural products from edible plants A Roy, L Lim, S Srivastava, Y Lu, J Song PloS one 12 (7), e0180632, 2017 | 101 | 2017 |
| A unified mechanism for LLPS of ALS/FTLD-causing FUS as well as its modulation by ATP and oligonucleic acids J Kang, L Lim, Y Lu, J Song PLoS biology 17 (6), e3000327, 2019 | 98 | 2019 |
| Structural characterization reveals that viperin is a radical S-adenosyl-L-methionine (SAM) enzyme G Shaveta, J Shi, VTK Chow, J Song Biochemical and biophysical research communications 391 (3), 1390-1395, 2010 | 97 | 2010 |
| Contribution of individual residues to formation of the native-like tertiary topology in the α-lactalbumin molten globule J Song, P Bai, L Luo, Z Peng Journal of molecular biology 280 (1), 167-174, 1998 | 93 | 1998 |
| Dynamically-driven enhancement of the catalytic machinery of the SARS 3C-like protease by the S284-T285-I286/A mutations on the extra domain L Lim, J Shi, Y Mu, J Song PloS one 9 (7), e101941, 2014 | 87 | 2014 |
| Crystal structure and NMR binding reveal that two small molecule antagonists target the high affinity ephrin-binding channel of the EphA4 receptor H Qin, J Shi, R Noberini, EB Pasquale, J Song Journal of Biological Chemistry 283 (43), 29473-29484, 2008 | 84 | 2008 |
| Insight into “insoluble proteins” with pure water J Song FEBS letters 583 (6), 953-959, 2009 | 82 | 2009 |
| ATP enhances at low concentrations but dissolves at high concentrations liquid-liquid phase separation (LLPS) of ALS/FTD-causing FUS J Kang, L Lim, J Song Biochemical and Biophysical Research Communications, 2018 | 69 | 2018 |
| ATP binds and inhibits the neurodegeneration-associated fibrillization of the FUS RRM domain J Kang, L Lim, J Song Communications Biology 2 (1), 223, 2019 | 64 | 2019 |
| Disruption of FAT10–MAD2 binding inhibits tumor progression SS Theng, W Wang, WC Mah, C Chan, J Zhuo, Y Gao, H Qin, L Lim, ... Proceedings of the National Academy of Sciences 111 (49), E5282-E5291, 2014 | 64 | 2014 |
| NMR for the design of functional mimetics of protein-protein interactions: one key is in the building of bridges J Song, F Ni Biochemistry and cell biology 76 (2-3), 177-188, 1998 | 64 | 1998 |
shi jiahaiAssistant Professor at National University of SingaporeVerified email at nus.edu.sg
shi jiahaiAssistant Professor at National University of SingaporeVerified email at nus.edu.sg