| Chalcone: a privileged structure in medicinal chemistry C Zhuang, W Zhang, C Sheng, W Zhang, C Xing, Z Miao Chemical reviews 117 (12), 7762-7810, 2017 | 1187 | 2017 |
| Fluorescent probes for the detection of hydrogen sulfide in biological systems W Xuan, C Sheng, Y Cao, W He, W Wang Angewandte Chemie International Edition 51 (10), 2282-2284, 2012 | 291 | 2012 |
| Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking C Sheng, W Zhang, H Ji, M Zhang, Y Song, H Xu, J Zhu, Z Miao, Q Jiang, ... Journal of medicinal chemistry 49 (8), 2512-2525, 2006 | 210 | 2006 |
| Structural simplification of natural products S Wang, G Dong, C Sheng Chemical Reviews 119 (6), 4180-4220, 2019 | 184 | 2019 |
| New lead structures in antifungal drug discovery C Sheng, W Zhang Current medicinal chemistry 18 (5), 733-766, 2011 | 174 | 2011 |
| Scaffold diversity inspired by the natural product evodiamine: discovery of highly potent and multitargeting antitumor agents S Wang, K Fang, G Dong, S Chen, N Liu, Z Miao, J Yao, J Li, W Zhang, ... Journal of Medicinal Chemistry 58 (16), 6678-6696, 2015 | 170 | 2015 |
| Molecular glues for targeted protein degradation: from serendipity to rational discovery G Dong, Y Ding, S He, C Sheng Journal of medicinal chemistry 64 (15), 10606-10620, 2021 | 169 | 2021 |
| New tricks for an old natural product: discovery of highly potent evodiamine derivatives as novel antitumor agents by systemic structure–activity relationship analysis and … G Dong, S Wang, Z Miao, J Yao, Y Zhang, Z Guo, W Zhang, C Sheng Journal of medicinal chemistry 55 (17), 7593-7613, 2012 | 166 | 2012 |
| State-of-the-art strategies for targeting protein–protein interactions by small-molecule inhibitors C Sheng, G Dong, Z Miao, W Zhang, W Wang Chemical Society Reviews 44 (22), 8238-8259, 2015 | 159 | 2015 |
| Structure-based de novo design, synthesis, and biological evaluation of non-azole inhibitors specific for lanosterol 14α-demethylase of fungi H Ji, W Zhang, M Zhang, M Kudo, Y Aoyama, Y Yoshida, C Sheng, ... Journal of medicinal chemistry 46 (4), 474-485, 2003 | 159 | 2003 |
| Selection of evodiamine as a novel topoisomerase I inhibitor by structure-based virtual screening and hit optimization of evodiamine derivatives as antitumor agents G Dong, C Sheng, S Wang, Z Miao, J Yao, W Zhang Journal of medicinal chemistry 53 (21), 7521-7531, 2010 | 152 | 2010 |
| Discovery, synthesis, and biological evaluation of orally active pyrrolidone derivatives as novel inhibitors of p53–MDM2 protein–protein interaction C Zhuang, Z Miao, L Zhu, G Dong, Z Guo, S Wang, Y Zhang, Y Wu, J Yao, ... Journal of medicinal chemistry 55 (22), 9630-9642, 2012 | 136 | 2012 |
| Aptamer‐PROTAC conjugates (APCs) for tumor‐specific targeting in breast cancer S He, F Gao, J Ma, H Ma, G Dong, C Sheng Angewandte Chemie 133 (43), 23487-23493, 2021 | 127 | 2021 |
| Three-Dimensional Model of Lanosterol 14α-Demethylase from Cryptococcus neoformans: Active-Site Characterization and Insights into Azole Binding C Sheng, Z Miao, H Ji, J Yao, W Wang, X Che, G Dong, J Lü, W Guo, ... Antimicrobial agents and chemotherapy 53 (8), 3487-3495, 2009 | 125 | 2009 |
| Potent dual BET/HDAC inhibitors for efficient treatment of pancreatic cancer S He, G Dong, Y Li, S Wu, W Wang, C Sheng Angewandte Chemie International Edition 59 (8), 3028-3032, 2020 | 112 | 2020 |
| Design, synthesis, and antihepatitis B virus activities of novel 2-pyridone derivatives Z Lv, C Sheng, T Wang, Y Zhang, J Liu, J Feng, H Sun, H Zhong, C Niu, ... Journal of medicinal chemistry 53 (2), 660-668, 2010 | 110 | 2010 |
| Tackling fungal resistance by biofilm inhibitors S Wu, Y Wang, N Liu, G Dong, C Sheng Journal of Medicinal Chemistry 60 (6), 2193-2211, 2017 | 107 | 2017 |
| Evaluation of HOCl-generating anticancer agents by an ultrasensitive dual-mode fluorescent probe D Shi, S Chen, B Dong, Y Zhang, C Sheng, TD James, Y Guo Chemical Science 10 (13), 3715-3722, 2019 | 102 | 2019 |
| Small molecule inhibitors simultaneously targeting cancer metabolism and epigenetics: discovery of novel nicotinamide phosphoribosyltransferase (NAMPT) and histone deacetylase … G Dong, W Chen, X Wang, X Yang, T Xu, P Wang, W Zhang, Y Rao, ... Journal of medicinal chemistry 60 (19), 7965-7983, 2017 | 101 | 2017 |
| Emerging new targets for the treatment of resistant fungal infections N Liu, J Tu, G Dong, Y Wang, C Sheng Journal of medicinal chemistry 61 (13), 5484-5511, 2018 | 100 | 2018 |
