Spirooxindoles: Promising scaffolds for anticancer agents B Yu, DQ Yu, HM Liu European journal of medicinal chemistry 97, 673-698, 2015 | 752 | 2015 |
Design and synthesis of novel 1, 2, 3-triazole-dithiocarbamate hybrids as potential anticancer agents YC Duan, YC Ma, E Zhang, XJ Shi, MM Wang, XW Ye, HM Liu European journal of medicinal chemistry 62, 11-19, 2013 | 285 | 2013 |
Triazole–dithiocarbamate based selective lysine specific demethylase 1 (LSD1) inactivators inhibit gastric cancer cell growth, invasion, and migration YC Zheng, YC Duan, JL Ma, RM Xu, X Zi, WL Lv, MM Wang, XW Ye, ... Journal of medicinal chemistry 56 (21), 8543-8560, 2013 | 239 | 2013 |
A systematic review of histone lysine‐specific demethylase 1 and its inhibitors YC Zheng, J Ma, Z Wang, J Li, B Jiang, W Zhou, X Shi, X Wang, W Zhao, ... Medicinal research reviews 35 (5), 1032-1071, 2015 | 210 | 2015 |
Isolation and structure elucidation of gymnemic acids, antisweet principles of Gymnema sylvestre HM LIU, F Kiuchi, Y Tsuda Chemical and Pharmaceutical Bulletin 40 (6), 1366-1375, 1992 | 177 | 1992 |
Chemical molecular‐based approach to overcome multidrug resistance in cancer by targeting P‐glycoprotein (P‐gp) H Zhang, H Xu, CR Ashby Jr, YG Assaraf, ZS Chen, HM Liu Medicinal research reviews 41 (1), 525-555, 2021 | 172 | 2021 |
Design, synthesis, and structure–activity relationship of novel LSD1 inhibitors based on pyrimidine–thiourea hybrids as potent, orally active antitumor agents LY Ma, YC Zheng, SQ Wang, B Wang, ZR Wang, LP Pang, M Zhang, ... Journal of medicinal chemistry 58 (4), 1705-1716, 2015 | 170 | 2015 |
Discovery of orally active anticancer candidate CFI-400945 derived from biologically promising spirooxindoles: Success and challenges B Yu, Z Yu, PP Qi, DQ Yu, HM Liu European Journal of Medicinal Chemistry 95, 35-40, 2015 | 156 | 2015 |
Synthesis and biological evaluation of novel steroidal [17, 16-d][1, 2, 4] triazolo [1, 5-a] pyrimidines LH Huang, YF Zheng, YZ Lu, CJ Song, YG Wang, B Yu, HM Liu Steroids 77 (6), 710-715, 2012 | 133 | 2012 |
Design, synthesis and antiproliferative activity studies of novel 1, 2, 3-triazole–dithiocarbamate–urea hybrids YC Duan, YC Zheng, XC Li, MM Wang, XW Ye, YY Guan, GZ Liu, ... European journal of medicinal chemistry 64, 99-110, 2013 | 128 | 2013 |
Targeting Brd4 for cancer therapy: inhibitors and degraders Y Duan, Y Guan, W Qin, X Zhai, B Yu, H Liu Medchemcomm 9 (11), 1779-1802, 2018 | 124 | 2018 |
Natural product-derived spirooxindole fragments serve as privileged substructures for discovery of new anticancer agents B Yu, YC Zheng, XJ Shi, PP Qi, HM Liu Anti-Cancer Agents in Medicinal Chemistry (Formerly Current Medicinal …, 2016 | 118 | 2016 |
p‐Coumaroyltriacetic acid synthase, a new homologue of chalcone synthase, from Hydrangea macrophylla var. thunbergii T Akiyama, M Shibuya, HM Liu, Y Ebizuka European journal of biochemistry 263 (3), 834-839, 1999 | 117 | 1999 |
High incidence and endemic spread of NDM-1-positive Enterobacteriaceae in Henan Province, China S Qin, Y Fu, Q Zhang, H Qi, JG Wen, H Xu, L Xu, L Zeng, H Tian, L Rong, ... Antimicrobial Agents and Chemotherapy 58 (8), 4275-4282, 2014 | 113 | 2014 |
Design and synthesis of novel 1, 2, 3-triazole-pyrimidine hybrids as potential anticancer agents LY Ma, LP Pang, B Wang, M Zhang, B Hu, DQ Xue, KP Shao, BL Zhang, ... European journal of medicinal chemistry 86, 368-380, 2014 | 108 | 2014 |
Design and synthesis of novel 1, 2, 3-triazole–pyrimidine–urea hybrids as potential anticancer agents LY Ma, B Wang, LP Pang, M Zhang, SQ Wang, YC Zheng, KP Shao, ... Bioorganic & Medicinal Chemistry Letters 25 (5), 1124-1128, 2015 | 106 | 2015 |
Synthesis of andrographolide derivatives: a new family of α-glucosidase inhibitors HW Xu, GF Dai, GZ Liu, JF Wang, HM Liu Bioorganic & medicinal chemistry 15 (12), 4247-4255, 2007 | 103 | 2007 |
USP7: novel drug target in cancer therapy Z Wang, W Kang, Y You, J Pang, H Ren, Z Suo, H Liu, Y Zheng Frontiers in Pharmacology 10, 427, 2019 | 102 | 2019 |
Studies on the novel α-glucosidase inhibitory activity and structure–activity relationships for andrographolide analogues GF Dai, HW Xu, JF Wang, FW Liu, HM Liu Bioorganic & medicinal chemistry letters 16 (10), 2710-2713, 2006 | 99 | 2006 |
Synthesis and biological evaluation of coumarin–1, 2, 3-triazole–dithiocarbamate hybrids as potent LSD1 inhibitors XW Ye, YC Zheng, YC Duan, MM Wang, B Yu, JL Ren, JL Ma, E Zhang, ... MedChemComm 5 (5), 650-654, 2014 | 93 | 2014 |