| The gene encoding the splicing factor SF2/ASF is a proto-oncogene R Karni, E de Stanchina, SW Lowe, R Sinha, D Mu, AR Krainer Nature structural & molecular biology 14 (3), 185-193, 2007 | 1013 | 2007 |
| The splicing factor SRSF1 regulates apoptosis and proliferation to promote mammary epithelial cell transformation O Anczuków, AZ Rosenberg, M Akerman, S Das, L Zhan, R Karni, ... Nature structural & molecular biology 19 (2), 220-228, 2012 | 457 | 2012 |
| Control of pancreatic β cell regeneration by glucose metabolism S Porat, N Weinberg-Corem, S Tornovsky-Babaey, R Schyr-Ben-Haroush, ... Cell metabolism 13 (4), 440-449, 2011 | 347 | 2011 |
| Long noncoding RNA MALAT1 promotes hepatocellular carcinoma development by SRSF1 upregulation and mTOR activation P Malakar, A Shilo, A Mogilevsky, I Stein, E Pikarsky, Y Nevo, ... Cancer research 77 (5), 1155-1167, 2017 | 288 | 2017 |
| Splicing factor hnRNP A2/B1 regulates tumor suppressor gene splicing and is an oncogenic driver in glioblastoma R Golan-Gerstl, M Cohen, A Shilo, SS Suh, A Bakàcs, L Coppola, R Karni Cancer research 71 (13), 4464-4472, 2011 | 253 | 2011 |
| Inhibition of pp60c-Src reduces Bcl-XL expression and reverses the transformed phenotype of cells overexpressing EGF and HER-2 receptors R Karni, R Jove, A Levitzki Oncogene 18 (33), 4654-4662, 1999 | 245 | 1999 |
| SF2/ASF autoregulation involves multiple layers of post-transcriptional and translational control S Sun, Z Zhang, R Sinha, R Karni, AR Krainer Nature structural & molecular biology 17 (3), 306-312, 2010 | 228 | 2010 |
| The splicing factor SRSF6 is amplified and is an oncoprotein in lung and colon cancers M Cohen‐Eliav, R Golan‐Gerstl, Z Siegfried, CL Andersen, K Thorsen, ... The Journal of Pathology 229 (4), 630-639, 2013 | 160 | 2013 |
| Identification of recurrent regulated alternative splicing events across human solid tumors M Danan-Gotthold, R Golan-Gerstl, E Eisenberg, K Meir, R Karni, ... Nucleic acids research 43 (10), 5130-5144, 2015 | 159 | 2015 |
| Long noncoding RNA MALAT1 regulates cancer glucose metabolism by enhancing mTOR-mediated translation of TCF7L2 P Malakar, I Stein, A Saragovi, R Winkler, N Stern-Ginossar, M Berger, ... Cancer research 79 (10), 2480-2493, 2019 | 158 | 2019 |
| Functional and prognostic significance of long non-coding RNA MALAT1 as a metastasis driver in ER negative lymph node negative breast cancer M Jadaliha, X Zong, P Malakar, T Ray, DK Singh, SM Freier, T Jensen, ... Oncotarget 7 (26), 40418, 2016 | 155 | 2016 |
| Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1α expression under normoxia R Karni, Y Dor, E Keshet, O Meyuhas, A Levitzki Journal of Biological Chemistry 277 (45), 42919-42925, 2002 | 149 | 2002 |
| TRPM2 mediates neutrophil killing of disseminated tumor cells M Gershkovitz, Y Caspi, T Fainsod-Levi, B Katz, J Michaeli, S Khawaled, ... Cancer research 78 (10), 2680-2690, 2018 | 143 | 2018 |
| The splicing-factor oncoprotein SF2/ASF activates mTORC1 R Karni, Y Hippo, SW Lowe, AR Krainer Proceedings of the National Academy of Sciences 105 (40), 15323-15327, 2008 | 137 | 2008 |
| S6K1 alternative splicing modulates its oncogenic activity and regulates mTORC1 V Ben-Hur, P Denichenko, Z Siegfried, A Maimon, A Krainer, B Davidson, ... Cell reports 3 (1), 103-115, 2013 | 129 | 2013 |
| Arginine methylation controls the subcellular localization and functions of the oncoprotein splicing factor SF2/ASF R Sinha, E Allemand, Z Zhang, R Karni, MP Myers, AR Krainer Molecular and cellular biology, 2010 | 118 | 2010 |
| Splicing factor hnRNP A2 activates the Ras-MAPK-ERK pathway by controlling A-Raf splicing in hepatocellular carcinoma development A Shilo, VB Hur, P Denichenko, I Stein, E Pikarsky, J Rauch, W Kolch, ... Rna 20 (4), 505-515, 2014 | 113 | 2014 |
| The role of alternative splicing in cancer drug resistance Z Siegfried, R Karni Current opinion in genetics & development 48, 16-21, 2018 | 105 | 2018 |
| The pp60c‐Src inhibitor PP1 is non‐competitive against ATP R Karni, S Mizrachi, E Reiss-Sklan, A Gazit, O Livnah, A Levitzki FEBS letters 537 (1-3), 47-52, 2003 | 104 | 2003 |
| Mnk2 alternative splicing modulates the p38-MAPK pathway and impacts Ras-induced transformation A Maimon, M Mogilevsky, A Shilo, R Golan-Gerstl, A Obiedat, V Ben-Hur, ... Cell reports 7 (2), 501-513, 2014 | 102 | 2014 |
