The DarTG toxin-antitoxin system provides phage defence by ADP-ribosylating viral DNA M LeRoux, S Srikant, GIC Teodoro, T Zhang, ML Littlehale, S Doron, ... Nature microbiology 7 (7), 1028-1040, 2022 | 83 | 2022 |
Direct activation of a bacterial innate immune system by a viral capsid protein T Zhang, H Tamman, K Coppieters’t Wallant, T Kurata, M LeRoux, ... Nature 612 (7938), 132-140, 2022 | 65 | 2022 |
Mechanics and pharmacology of substrate selection and transport by eukaryotic ABC exporters S Srikant, R Gaudet Nature structural & molecular biology 26 (9), 792-801, 2019 | 59 | 2019 |
The evolution of a counter-defense mechanism in a virus constrains its host range S Srikant, CK Guegler, MT Laub Elife 11, e79549, 2022 | 35 | 2022 |
Evolutionary history of ATP‐binding cassette proteins S Srikant Febs Letters 594 (23), 3882-3897, 2020 | 35 | 2020 |
Selecting for altered substrate specificity reveals the evolutionary flexibility of ATP-binding cassette transporters S Srikant, R Gaudet, AW Murray Current Biology 30 (9), 1689-1702. e6, 2020 | 18 | 2020 |
Behaviour of hydrogen bonding and structure of poly (acrylic acid) in water–ethanol solution investigated by explicit ion molecular dynamics simulations S Srikant, SS Muralidharan, U Natarajan Molecular Simulation 39 (2), 145-153, 2013 | 14 | 2013 |
D-helix influences dimerization of the ATP-binding cassette (ABC) transporter associated with antigen processing 1 (TAP1) nucleotide-binding domain AS Vakkasoglu, S Srikant, R Gaudet PloS one 12 (5), e0178238, 2017 | 9 | 2017 |
Direct activation of an innate immune system in bacteria by a viral capsid protein T Zhang, H Tamman, K Coppieters’t Wallant, T Kurata, M LeRoux, ... BioRxiv, 2022.05. 30.493996, 2022 | 6 | 2022 |
Beyond the reach of homology: Successive computational filters find yeast pheromone genes S Srikant, R Gaudet, AW Murray bioRxiv, 2021.09. 28.462209, 2021 | 2 | 2021 |
Extending the reach of homology by using successive computational filters to find yeast pheromone genes S Srikant, R Gaudet, AW Murray Current Biology 33 (19), 4098-4110. e3, 2023 | 1 | 2023 |
Natural transformation protein ComFA exhibits single-stranded DNA translocase activity HR Foster, X Lin, S Srikant, RR Cueny, TG Falbel, JL Keck, R Gaudet, ... Journal of Bacteriology 204 (3), e00518-21, 2022 | 1 | 2022 |
Evolution of substrate selectivity in ATP binding cassette exporters S Srikant Harvard University, 2019 | 1 | 2019 |
Horizontal transfer of phage-defense genes can stably maintain their diversity in a microbial pan-genome despite continuous extinction and turnover of genomes W Cui, J Fendley, S Srikant, B Shraiman Bulletin of the American Physical Society, 2024 | | 2024 |
A model of pan-immunity maintenance by horizontal gene transfer in the ecological dynamics of bacteria and phages W Cui, JM Fendley, S Srikant, B Shraiman arXiv preprint arXiv:2402.19388, 2024 | | 2024 |
A phage-encoded RNA-binding protein inhibits the antiviral activity of a toxin–antitoxin system CK Guegler, GIC Teodoro, S Srikant, K Chetlapalli, CR Doering, ... Nucleic Acids Research 52 (3), 1298-1312, 2024 | | 2024 |