| A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation H Okabe, SH Lee, J Phuchareon, DG Albertson, F McCormick, O Tetsu PloS one 1 (1), e128, 2006 | 227 | 2006 |
| Pharmacologic inhibition of RAF→ MEK→ ERK signaling elicits pancreatic cancer cell cycle arrest through induced expression of p27Kip1 S Gysin, SH Lee, NM Dean, M McMahon Cancer research 65 (11), 4870-4880, 2005 | 176 | 2005 |
| Tpr directly binds to Mad1 and Mad2 and is important for the Mad1–Mad2-mediated mitotic spindle checkpoint SH Lee, H Sterling, A Burlingame, F McCormick Genes & development 22 (21), 2926-2931, 2008 | 173 | 2008 |
| The p110α and p110β isoforms of PI3K play divergent roles in mammary gland development and tumorigenesis T Utermark, T Rao, H Cheng, Q Wang, SH Lee, ZC Wang, JD Iglehart, ... Genes & development 26 (14), 1573-1586, 2012 | 146 | 2012 |
| IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation JK Cheong, NT Hung, H Wang, P Tan, PM Voorhoeve, SH Lee, ... Oncogene 30 (22), 2558-2569, 2011 | 134 | 2011 |
| IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ϵ and Wnt/β-catenin independent inhibition of mitotic spindle formation JK Cheong, NT Hung, H Wang, P Tan, PM Voorhoeve, SH Lee, ... Oncogene 30 (22), 2558-2569, 2011 | 133 | 2011 |
| IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ɛ and Wnt/β-catenin independent inhibition of mitotic spindle formation JK Cheong, NT Hung, H Wang, P Tan, PM Voorhoeve, SH Lee, ... Oncogene 30 (22), 2558-2569, 2011 | 133 | 2011 |
| The chromosomal passenger complex (CPC) as a key orchestrator of orderly mitotic exit and cytokinesis M Kitagawa, SH Lee Frontiers in cell and developmental biology 3, 14, 2015 | 132 | 2015 |
| Skp2 suppresses p53-dependent apoptosis by inhibiting p300 M *Kitagawa, SH *Lee, F McCormick, (* co-first) Molecular cell 29 (2), 217-231, 2008 | 130 | 2008 |
| p97/DAP5 is a ribosome‐associated factor that facilitates protein synthesis and cell proliferation by modulating the synthesis of cell cycle proteins SH Lee, F McCormick The EMBO journal 25 (17), 4008-4019, 2006 | 126 | 2006 |
| BUBR1 recruits PP2A via the B56 family of targeting subunits to promote chromosome congression P Xu, EA Raetz, M Kitagawa, DM Virshup, SH Lee Biology open 2 (5), 479-486, 2013 | 123 | 2013 |
| Characterization of the nuclear import and export functions of IκBε SH Lee, M Hannink Journal of Biological Chemistry 277 (26), 23358-23366, 2002 | 98 | 2002 |
| E2F-1 transcriptional activity is a critical determinant of Mdm2 antagonist-induced apoptosis in human tumor cell lines M Kitagawa, M Aonuma, SH Lee, S Fukutake, F McCormick Oncogene 27 (40), 5303-5314, 2008 | 93 | 2008 |
| Cdk1 coordinates timely activation of MKlp2 kinesin with relocation of the chromosome passenger complex for cytokinesis M Kitagawa, SYS Fung, UFS Hameed, H Goto, M Inagaki, SH Lee Cell reports 7 (1), 166-179, 2014 | 75 | 2014 |
| Targeting Aurora B to the equatorial cortex by MKlp2 is required for cytokinesis M Kitagawa, SYS Fung, N Onishi, H Saya, SH Lee PloS one 8 (6), e64826, 2013 | 72 | 2013 |
| Crystal structure of a PP2A B56-BubR1 complex and its implications for PP2A substrate recruitment and localization J Wang, Z Wang, T Yu, H Yang, DM Virshup, GJPL Kops, SH Lee, W Zhou, ... Protein & cell 7 (7), 516-526, 2016 | 68 | 2016 |
| Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality M Kitagawa, PJ Liao, KH Lee, J Wong, SC Shang, N Minami, ... Nature communications 8 (1), 2200, 2017 | 67 | 2017 |
| Downregulation of Skp2 and p27/Kip1 synergistically induces apoptosis in T98G glioblastoma cells SH Lee, F McCormick Journal of molecular medicine 83, 296-307, 2005 | 67 | 2005 |
| Molecular mechanisms that regulate transcription factor localization suggest new targets for drug development SH Lee, M Hannink Advanced drug delivery reviews 55 (6), 717-731, 2003 | 51 | 2003 |
| The N-terminal nuclear export sequence of IκBα is required for RanGTP-dependent binding to CRM1 SH Lee, M Hannink Journal of Biological Chemistry 276 (26), 23599-23606, 2001 | 46 | 2001 |
