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Maria Zagorulya
Maria Zagorulya
Verified email at mit.edu
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Year
Increased demand for NAD+ relative to ATP drives aerobic glycolysis
A Luengo, Z Li, DY Gui, LB Sullivan, M Zagorulya, BT Do, R Ferreira, ...
Molecular cell 81 (4), 691-707. e6, 2021
2852021
Direct and indirect regulators of epithelial–mesenchymal transition–mediated immunosuppression in breast carcinomas
A Dongre, M Rashidian, EN Eaton, F Reinhardt, P Thiru, M Zagorulya, ...
Cancer discovery 11 (5), 1286-1305, 2021
852021
Lack of CD8+ T cell effector differentiation during priming mediates checkpoint blockade resistance in non–small cell lung cancer
BL Horton, DM Morgan, N Momin, M Zagorulya, E Torres-Mejia, ...
Science Immunology 6 (64), eabi8800, 2021
782021
Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer
M Zagorulya, L Yim, DM Morgan, A Edwards, E Torres-Mejia, N Momin, ...
Immunity 56 (2), 386-405. e10, 2023
322023
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ...
The EMBO Journal 41 (21), e110393, 2022
222022
Impact of anatomic site on antigen-presenting cells in cancer
M Zagorulya, E Duong, S Spranger
Journal for Immunotherapy of Cancer 8 (2), 2020
162020
Sensitivity of primary fibroblasts in culture to atmospheric oxygen does not correlate with species lifespan
A Patrick, M Seluanov, C Hwang, J Tam, T Khan, A Morgenstern, ...
Aging 8 (5), 841-847, 2016
142016
Once upon a prime: DCs shape cancer immunity
M Zagorulya, S Spranger
Trends in Cancer 9 (2), 172-184, 2023
112023
Direct and Indirect Regulators of Epithelial-Mesenchymal Transition (EMT)-mediated Immunosuppression in Breast Carcinomas [Internet]. Cancer Discov. 2020
A Dongre, M Rashidian, EN Eaton, F Reinhardt, P Thiru, M Zagorulya, ...
CD-20-0603.[PubMed][CrossRef][Google Scholar], 0
9
A rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
M Simon, J Yang, J Gigas, EJ Earley, E Hillpot, L Zhang, M Zagorulya, ...
The EMBO Journal 42 (3), e113326, 2023
32023
1087 Addition of IL-2 overcomes lung tumor resistance to IL-12 by coordinating cytotoxic and regulatory T cell responses
B Horton, M Zagorulya, N Momin, Y Agarwal, K Wittrup, S Spranger
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
22022
Overcoming lung cancer immunotherapy resistance by combining nontoxic variants of IL-12 and IL-2
BL Horton, AD D’Souza, M Zagorulya, CV McCreery, GC Abhiraman, ...
JCI insight 8 (19), 2023
12023
232 The epithelial-to-mesenchymal transition (EMT) contributes to immunosuppression in breast carcinomas and regulates their response to immune checkpoint blockade
A Dongre, R Weinberg, M Rashidian, E Eaton, F Reinhardt, P Thiru, ...
Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020
12020
Sleep fights infection
M Zagorulya
J of Young Investigators, 2015
12015
Differentiation and Expansion of Tumor-Infiltrating T Cell Clonotypes Occurs in the Spleen Following Immune Checkpoint Blockade
DM Morgan, BL Horton, M Zagorulya, JC Love, S Spranger
bioRxiv, 2023.09. 04.555982, 2023
2023
Dendritic cell dysfunction restrains cytotoxic T cell responses against cancer
M Zagorulya
Massachusetts Institute of Technology, 2023
2023
1052 Tissue-specific interferon-gamma drives regulatory T-cells to restrain DC1-mediated priming of cytotoxic T-cells against lung cancer
M Zagorulya, L Yim, D Morgan, A Edwards, E Torres-Mejia, N Momin, ...
Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022
2022
664 Pulmonary priming of tumor-reactive CD8+ T cells by DC1 is impaired by regulatory T cells
M Zagorulya, D Morgan, L Yim, B Horton, E Torres-Mejia, S Spranger
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), A692-A692, 2021
2021
303 Non-functional T cell responses in non-small cell lung cancer are induced during tumor antigen-specific T cell priming in the mediastinal lymph node
B Horton, D Morgan, E Torres-Mejia, M Zagorulya, V Bhandarkar, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021
2021
Potentiating the efficacy of immune checkpoint blockade by targeting the epithelial-to-mesenchymal transition (EMT) in breast carcinomas.
A Dongre, M Rashidian, EN Eaton, F Reinhardt, P Thiru, M Zagorulya, ...
CANCER IMMUNOLOGY RESEARCH 9 (2), 2021
2021
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