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Adrien Le Thomas
Adrien Le Thomas
Verified email at gene.com
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Cited by
Cited by
Year
Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state
A Le Thomas, AK Rogers, A Webster, GK Marinov, SE Liao, EM Perkins, ...
Genes & development 27 (4), 390-399, 2013
5052013
Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing
A Le Thomas, E Stuwe, S Li, J Du, G Marinov, N Rozhkov, YCA Chen, ...
Genes & Development 28 (15), 1667-1680, 2014
2112014
Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors
YCA Chen, E Stuwe, Y Luo, M Ninova, A Le Thomas, E Rozhavskaya, ...
Molecular cell 63 (1), 97-109, 2016
1152016
To be or not to be a piRNA: genomic origin and processing of piRNAs
A Le Thomas, KF Tóth, AA Aravin
Genome biology 15 (1), 204, 2014
1142014
Disruption of IRE1α through its kinase domain attenuates multiple myeloma
JM Harnoss, A Le Thomas, A Shemorry, SA Marsters, DA Lawrence, M Lu, ...
Proceedings of the National Academy of Sciences 116 (33), 16420-16429, 2019
922019
A Transgenerational Process Defines piRNA Biogenesis in< i> Drosophila virilis</i>
A Le Thomas, GK Marinov, AA Aravin
Cell Reports, 2014
602014
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment
JM Harnoss, A Le Thomas, M Reichelt, O Guttman, TD Wu, SA Marsters, ...
Cancer Research 80 (11), 2368-2379, 2020
562020
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α
A Le Thomas, E Ferri, S Marsters, JM Harnoss, DA Lawrence, ...
Nature Communications 12 (1), 1-15, 2021
282021
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands
E Ferri, A Le Thomas, HA Wallweber, ES Day, BT Walters, SE Kaufman, ...
Nature Communications 11 (1), 1-15, 2020
262020
Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation
O Guttman, A Le Thomas, S Marsters, DA Lawrence, L Gutgesell, ...
Journal of Cell Biology 221 (6), e202111068, 2022
192022
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay
F Cairrão, CC Santos, A Le Thomas, S Marsters, A Ashkenazi, ...
Nature communications 13 (1), 1-13, 2022
122022
Neuronal regulated ire-1-dependent mRNA decay controls germline differentiation in Caenorhabditis elegans
M Levi-Ferber, R Shalash, A Le-Thomas, Y Salzberg, M Shurgi, ...
Elife 10, e65644, 2021
82021
Noncanonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α promotes cancer-cell survival
A Le Thomas, E Ferri, S Marsters, JM Harnoss, Z Modrusan, W Li, ...
bioRxiv, 2021
82021
A Framework for piRNA Cluster Manipulation
I Olovnikov, A Le Thomas, AA Aravin
PIWI-Interacting RNAs: Methods and Protocols, 47-58, 2014
42014
Antigen-derived peptides directly engage the unfolded-protein sensor IRE1α to curb cross-presentation by dendritic cells
O Guttman, A Le Thomas, SA Marsters, DA Lawrence, L Gutgesell, ...
bioRxiv, 2021
2021
Neuronal regulated Ire1-dependent mRNA decay controls germline differentiation in C. elegans
M Levi-Ferber, R Shalash, A Le-Thomas, Y Salzberg, M Shurgi, ...
bioRxiv, 2020
2020
Piwi function and piRNA cluster regulation: Drosophila melanogaster
A Le Thomas
Université Pierre et Marie Curie-Paris VI, 2014
2014
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Articles 1–17