Piwi induces piRNA-guided transcriptional silencing and establishment of a repressive chromatin state A Le Thomas, AK Rogers, A Webster, GK Marinov, SE Liao, EM Perkins, ... Genes & development 27 (4), 390-399, 2013 | 505 | 2013 |
Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing A Le Thomas, E Stuwe, S Li, J Du, G Marinov, N Rozhkov, YCA Chen, ... Genes & Development 28 (15), 1667-1680, 2014 | 211 | 2014 |
Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors YCA Chen, E Stuwe, Y Luo, M Ninova, A Le Thomas, E Rozhavskaya, ... Molecular cell 63 (1), 97-109, 2016 | 115 | 2016 |
To be or not to be a piRNA: genomic origin and processing of piRNAs A Le Thomas, KF Tóth, AA Aravin Genome biology 15 (1), 204, 2014 | 114 | 2014 |
Disruption of IRE1α through its kinase domain attenuates multiple myeloma JM Harnoss, A Le Thomas, A Shemorry, SA Marsters, DA Lawrence, M Lu, ... Proceedings of the National Academy of Sciences 116 (33), 16420-16429, 2019 | 92 | 2019 |
A Transgenerational Process Defines piRNA Biogenesis in< i> Drosophila virilis</i> A Le Thomas, GK Marinov, AA Aravin Cell Reports, 2014 | 60 | 2014 |
IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment JM Harnoss, A Le Thomas, M Reichelt, O Guttman, TD Wu, SA Marsters, ... Cancer Research 80 (11), 2368-2379, 2020 | 56 | 2020 |
Decoding non-canonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α A Le Thomas, E Ferri, S Marsters, JM Harnoss, DA Lawrence, ... Nature Communications 12 (1), 1-15, 2021 | 28 | 2021 |
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands E Ferri, A Le Thomas, HA Wallweber, ES Day, BT Walters, SE Kaufman, ... Nature Communications 11 (1), 1-15, 2020 | 26 | 2020 |
Antigen-derived peptides engage the ER stress sensor IRE1α to curb dendritic cell cross-presentation O Guttman, A Le Thomas, S Marsters, DA Lawrence, L Gutgesell, ... Journal of Cell Biology 221 (6), e202111068, 2022 | 19 | 2022 |
Pumilio protects Xbp1 mRNA from regulated Ire1-dependent decay F Cairrão, CC Santos, A Le Thomas, S Marsters, A Ashkenazi, ... Nature communications 13 (1), 1-13, 2022 | 12 | 2022 |
Neuronal regulated ire-1-dependent mRNA decay controls germline differentiation in Caenorhabditis elegans M Levi-Ferber, R Shalash, A Le-Thomas, Y Salzberg, M Shurgi, ... Elife 10, e65644, 2021 | 8 | 2021 |
Noncanonical mRNA decay by the endoplasmic-reticulum stress sensor IRE1α promotes cancer-cell survival A Le Thomas, E Ferri, S Marsters, JM Harnoss, Z Modrusan, W Li, ... bioRxiv, 2021 | 8 | 2021 |
A Framework for piRNA Cluster Manipulation I Olovnikov, A Le Thomas, AA Aravin PIWI-Interacting RNAs: Methods and Protocols, 47-58, 2014 | 4 | 2014 |
Antigen-derived peptides directly engage the unfolded-protein sensor IRE1α to curb cross-presentation by dendritic cells O Guttman, A Le Thomas, SA Marsters, DA Lawrence, L Gutgesell, ... bioRxiv, 2021 | | 2021 |
Neuronal regulated Ire1-dependent mRNA decay controls germline differentiation in C. elegans M Levi-Ferber, R Shalash, A Le-Thomas, Y Salzberg, M Shurgi, ... bioRxiv, 2020 | | 2020 |
Piwi function and piRNA cluster regulation: Drosophila melanogaster A Le Thomas Université Pierre et Marie Curie-Paris VI, 2014 | | 2014 |