Alastair Droop
Alastair Droop
Wellcome Sanger Institute
Verified email at - Homepage
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Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions
R Birnie, SD Bryce, C Roome, V Dussupt, A Droop, SH Lang, PA Berry, ...
Genome biology 9 (5), 1-13, 2008
Genomic subtypes of non-invasive bladder cancer with distinct metabolic profile and female gender bias in KDM6A mutation frequency
CD Hurst, O Alder, FM Platt, A Droop, LF Stead, JE Burns, GJ Burghel, ...
Cancer cell 32 (5), 701-715. e7, 2017
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa
A Buskin, L Zhu, V Chichagova, B Basu, S Mozaffari-Jovin, D Dolan, ...
Nature communications 9 (1), 1-19, 2018
Prediction of clinical outcome in glioblastoma using a biologically relevant nine-microRNA signature
J Hayes, H Thygesen, C Tumilson, A Droop, M Boissinot, TA Hughes, ...
Molecular oncology 9 (3), 704-714, 2015
β-Catenin–mediated immune evasion pathway frequently operates in primary cutaneous melanomas
J Nsengimana, J Laye, A Filia, S O’Shea, S Muralidhar, J Poźniak, ...
The Journal of clinical investigation 128 (5), 2048-2063, 2018
Loss of CSL unlocks a hypoxic response and enhanced tumor growth potential in breast cancer cells
EB Braune, YL Tsoi, YP Phoon, S Landor, HS Cascales, D Ramsköld, ...
Stem cell reports 6 (5), 643-651, 2016
Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance
GC Rivera-Gonzalez, AP Droop, HJ Rippon, K Tiemann, D Pellacani, ...
Nucleic acids research 40 (11), 4825-4840, 2012
KHS101 disrupts energy metabolism in human glioblastoma cells and reduces tumor growth in mice
ES Polson, VB Kuchler, C Abbosh, EM Ross, RK Mathew, HA Beard, ...
Science translational medicine 10 (454), 2018
Genetic and environmental determinants of immune response to cutaneous melanoma
J Poźniak, J Nsengimana, JP Laye, SJ O’Shea, JMS Diaz, AP Droop, ...
Cancer research 79 (10), 2684-2696, 2019
DNA hypermethylation in prostate cancer is a consequence of aberrant epithelial differentiation and hyperproliferation
D Pellacani, D Kestoras, AP Droop, FM Frame, PA Berry, MG Lawrence, ...
Cell Death & Differentiation 21 (5), 761-773, 2014
Engineering Simulations as Scientific Instruments: A Pattern Language: With Kieran Alden, Paul S. Andrews, James L. Bown, Alastair Droop, Richard B. Greaves, Mark Read, Adam T …
S Stepney, FAC Polack
Springer, 2018
The calcium sensor STIM1 is regulated by androgens in prostate stromal cells
PA Berry, R Birnie, AP Droop, NJ Maitland, AT Collins
The Prostate 71 (15), 1646-1655, 2011
Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq
C Conway, JL Graham, P Chengot, C Daly, R Chalkley, L Ross, A Droop, ...
Oncotarget 6 (37), 40186, 2015
The mutational signature profile of known and suspected human carcinogens in mice
L Riva, AR Pandiri, YR Li, A Droop, J Hewinson, MA Quail, V Iyer, ...
Nature genetics 52 (11), 1189-1197, 2020
Simulation validation: exploring the suitability of a simulation of cell division and differentiation in the prostate
FAC Polack, A Droop, P Garnett, T Ghetiu, S Stepney
Proceedings of the 2011 Workshop on Complex Systems Modelling and Simulation …, 2011
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma
HJ Close, LF Stead, J Nsengimana, KA Reilly, A Droop, H Wurdak, ...
Clinical & Experimental Immunology 200 (1), 33-44, 2020
fqtools: an efficient software suite for modern FASTQ file manipulation
AP Droop
Bioinformatics 32 (12), 1883-1884, 2016
Prognostic microRNAs in high-grade glioma reveal a link to oligodendrocyte precursor differentiation
J Hayes, H Thygesen, A Droop, TA Hughes, D Westhead, SE Lawler, ...
Oncoscience 2 (3), 252, 2015
Multiple model simulation: modelling cell division and differentiation in the prostate
A Droop, P Garnett, FAC Polack, S Stepney
Proceedings of the 2011 Workshop on Complex Systems Modelling and Simulation …, 2011
A case-matched gender comparison transcriptomic screen identifies eIF4E and eIF5 as potential prognostic markers in male breast cancer
MP Humphries, SS Rajan, A Droop, CAB Suleman, C Carbone, C Nilsson, ...
Clinical Cancer Research 23 (10), 2575-2583, 2017
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