| Lineage-specific and single-cell chromatin accessibility charts human hematopoiesis and leukemia evolution MR Corces, JD Buenrostro, B Wu, PG Greenside, SM Chan, JL Koenig, ... Nature genetics 48 (10), 1193-1203, 2016 | 1053 | 2016 |
| Isocitrate dehydrogenase 1 and 2 mutations induce BCL-2 dependence in acute myeloid leukemia SM Chan, D Thomas, MR Corces-Zimmerman, S Xavy, S Rastogi, ... Nature medicine 21 (2), 178-184, 2015 | 566 | 2015 |
| Isocitrate dehydrogenase mutations in myeloid malignancies BC Medeiros, AT Fathi, CD DiNardo, DA Pollyea, SM Chan, R Swords Leukemia 31 (2), 272-281, 2017 | 376 | 2017 |
| Circulating tumor DNA and liquid biopsy in oncology DW Cescon, SV Bratman, SM Chan, LL Siu Nature Cancer 1 (3), 276-290, 2020 | 370 | 2020 |
| Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia SM Chan, AP Weng, R Tibshirani, JC Aster, PJ Utz Blood, The Journal of the American Society of Hematology 110 (1), 278-286, 2007 | 321 | 2007 |
| Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or … X Shi, I Kachirskaia, KL Walter, JHA Kuo, A Lake, F Davrazou, SM Chan, ... Journal of Biological Chemistry 282 (4), 2450-2455, 2007 | 307 | 2007 |
| Selective tyrosine kinase inhibition by imatinib mesylate for the treatment of autoimmune arthritis RT Paniagua, O Sharpe, PP Ho, SM Chan, A Chang, JP Higgins, ... The Journal of clinical investigation 116 (10), 2633-2642, 2006 | 255 | 2006 |
| Protein microarrays for multiplex analysis of signal transduction pathways SM Chan, J Ermann, L Su, CG Fathman, PJ Utz Nature medicine 10 (12), 1390-1396, 2004 | 246 | 2004 |
| Role of antigen-presenting cells in mediating tolerance and autoimmunity KM Garza, SM Chan, R Suri, LT Nguyen, B Odermatt, SP Schoenberger, ... The Journal of Experimental Medicine 191 (11), 2021-2028, 2000 | 206 | 2000 |
| Biological and clinical consequences of NPM1 mutations in AML EM Heath, SM Chan, MD Minden, T Murphy, LI Shlush, AD Schimmer Leukemia 31 (4), 798-807, 2017 | 205 | 2017 |
| Leukemia-associated cohesin mutants dominantly enforce stem cell programs and impair human hematopoietic progenitor differentiation C Mazumdar, Y Shen, S Xavy, F Zhao, A Reinisch, R Li, MR Corces, ... Cell stem cell 17 (6), 675-688, 2015 | 205 | 2015 |
| Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes P Matre, J Velez, R Jacamo, Y Qi, X Su, T Cai, SM Chan, A Lodi, ... Oncotarget 7 (48), 79722, 2016 | 168 | 2016 |
| Inhibition of mitochondrial translation overcomes venetoclax resistance in AML through activation of the integrated stress response D Sharon, S Cathelin, S Mirali, JM Di Trani, DJ Yanofsky, KA Keon, ... Science translational medicine 11 (516), eaax2863, 2019 | 149 | 2019 |
| Multiplexed protein array platforms for analysis of autoimmune diseases I Balboni, SM Chan, M Kattah, JD Tenenbaum, AJ Butte, PJ Utz Annu. Rev. Immunol. 24, 391-418, 2006 | 144 | 2006 |
| Role of DNMT3A, TET2, and IDH1/2 mutations in pre-leukemic stem cells in acute myeloid leukemia SM Chan, R Majeti International journal of hematology 98, 648-657, 2013 | 143 | 2013 |
| An array of possibilities for the study of autoimmunity CG Fathman, L Soares, SM Chan, PJ Utz Nature 435 (7042), 605-611, 2005 | 136 | 2005 |
| Superenhancer analysis defines novel epigenomic subtypes of non-APL AML, including an RARα dependency targetable by SY-1425, a potent and selective RARα agonist MR McKeown, MR Corces, ML Eaton, C Fiore, E Lee, JT Lopez, ... Cancer discovery 7 (10), 1136-1153, 2017 | 132 | 2017 |
| Murine CD4+ CD25+ regulatory T cells fail to undergo chromatin remodeling across the proximal promoter region of the IL-2 gene L Su, RJ Creusot, EM Gallo, SM Chan, PJ Utz, CG Fathman, J Ermann The Journal of Immunology 173 (8), 4994-5001, 2004 | 107 | 2004 |
| Relapse-fated latent diagnosis subclones in acute B lineage leukemia are drug tolerant and possess distinct metabolic programs SM Dobson, L García-Prat, RJ Vanner, J Wintersinger, E Waanders, Z Gu, ... Cancer discovery 10 (4), 568-587, 2020 | 89 | 2020 |
| Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data S Sinha, D Thomas, S Chan, Y Gao, D Brunen, D Torabi, A Reinisch, ... Nature communications 8 (1), 15580, 2017 | 84 | 2017 |
