Wakabayashi Nobunao
Wakabayashi Nobunao
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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
K Itoh, N Wakabayashi, Y Katoh, T Ishii, K Igarashi, JD Engel, ...
Genes & development 13 (1), 76-86, 1999
Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway
TW Kensler, N Wakabayashi, S Biswal
Annu. Rev. Pharmacol. Toxicol. 47, 89-116, 2007
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
AT Dinkova-Kostova, WD Holtzclaw, RN Cole, K Itoh, N Wakabayashi, ...
Proceedings of the National Academy of Sciences 99 (18), 11908-11913, 2002
Protection against electrophile and oxidant stress by induction of the phase 2 response: fate of cysteines of the Keap1 sensor modified by inducers
N Wakabayashi, AT Dinkova-Kostova, WD Holtzclaw, MI Kang, ...
Proceedings of the National Academy of Sciences 101 (7), 2040-2045, 2004
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
N Wakabayashi, K Itoh, J Wakabayashi, H Motohashi, S Noda, ...
Nature genetics 35 (3), 238-245, 2003
Keap1 regulates both cytoplasmic‐nuclear shuttling and degradation of Nrf2 in response to electrophiles
K Itoh, N Wakabayashi, Y Katoh, T Ishii, T O'Connor, M Yamamoto
Genes to cells 8 (4), 379-391, 2003
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis
D Malhotra, E Portales-Casamar, A Singh, S Srivastava, D Arenillas, ...
Nucleic acids research 38 (17), 5718-5734, 2010
Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway: identification of novel gene clusters for cell survival
MK Kwak, N Wakabayashi, K Itoh, H Motohashi, M Yamamoto, ...
Journal of Biological Chemistry 278 (10), 8135-8145, 2003
The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice
J Wakabayashi, Z Zhang, N Wakabayashi, Y Tamura, M Fukaya, ...
Journal of Cell Biology 186 (6), 805-816, 2009
Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes
MI Kang, A Kobayashi, N Wakabayashi, SG Kim, M Yamamoto
Proceedings of the National Academy of Sciences 101 (7), 2046-2051, 2004
When NRF2 talks, who's listening?
N Wakabayashi, SL Slocum, JJ Skoko, S Shin, TW Kensler
Antioxidants & redox signaling 13 (11), 1649-1663, 2010
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
MK Kwak, N Wakabayashi, JL Greenlaw, M Yamamoto, TW Kensler
Molecular and cellular biology 23 (23), 8786-8794, 2003
Nrf2: friend or foe for chemoprevention?
TW Kensler, N Wakabayashi
Carcinogenesis 31 (1), 90-99, 2010
Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress
CJ Harvey, RK Thimmulappa, A Singh, DJ Blake, G Ling, N Wakabayashi, ...
Free Radical Biology and Medicine 46 (4), 443-453, 2009
Regulatory mechanisms of cellular response to oxidative stress
K Itoh, T Ishii, N Wakabayashi, M Yamamoto
Free radical research 31 (4), 319-324, 1999
Chemoprevention through the Keap1–Nrf2 signaling pathway by phase 2 enzyme inducers
MK Kwak, N Wakabayashi, TW Kensler
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 555 (1 …, 2004
NRF2 modulates aryl hydrocarbon receptor signaling: influence on adipogenesis
S Shin, N Wakabayashi, V Misra, S Biswal, GH Lee, ES Agoston, ...
Molecular and cellular biology 27 (20), 7188-7197, 2007
Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis
A Singh, C Happel, SK Manna, G Acquaah-Mensah, J Carrerero, S Kumar, ...
The Journal of clinical investigation 123 (7), 2921-2934, 2013
Role of Nrf2 in prevention of high-fat diet-induced obesity by synthetic triterpenoid CDDO-imidazolide
S Shin, J Wakabayashi, MS Yates, N Wakabayashi, PM Dolan, S Aja, ...
European journal of pharmacology 620 (1-3), 138-144, 2009
Keap1, the sensor for electrophiles and oxidants that regulates the phase 2 response, is a zinc metalloprotein
AT Dinkova-Kostova, WD Holtzclaw, N Wakabayashi
Biochemistry 44 (18), 6889-6899, 2005
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