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Alastair J Florence
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A strategy for producing predicted polymorphs: catemeric carbamazepine form V
JB Arlin, LS Price, SL Price, AJ Florence
Chemical Communications 47 (25), 7074-7076, 2011
2452011
Oscillatory flow reactors (OFRs) for continuous manufacturing and crystallization
T McGlone, NEB Briggs, CA Clark, CJ Brown, J Sefcik, AJ Florence
Organic Process Research & Development 19 (9), 1186-1202, 2015
2382015
Achieving continuous manufacturing: Technologies and approaches for synthesis, workup, and isolation of drug substance. May 20–21, 2014 Continuous Manufacturing Symposium
IR Baxendale, RD Braatz, BK Hodnett, KF Jensen, MD Johnson, ...
Journal of pharmaceutical sciences 104 (3), 781-791, 2015
2262015
Continuous manufacturing in pharmaceutical process development and manufacturing
CL Burcham, AJ Florence, MD Johnson
Annual review of chemical and biomolecular engineering 9 (1), 253-281, 2018
1692018
A single-crystal neutron diffraction study of the temperature dependence of hydrogen-atom disorder in benzoic acid dimers
CC Wilson, N Shankland, AJ Florence
Journal of the Chemical Society, Faraday Transactions 92 (24), 5051-5057, 1996
1631996
An automated parallel crystallisation search for predicted crystal structures and packing motifs of carbamazepine
AJ Florence, A Johnston, SL Price, H Nowell, AR Kennedy, N Shankland
Journal of pharmaceutical sciences 95 (9), 1918-1930, 2006
1522006
Exploring the experimental and computed crystal energy landscape of olanzapine
RM Bhardwaj, LS Price, SL Price, SM Reutzel-Edens, GJ Miller, ...
Crystal growth & design 13 (4), 1602-1617, 2013
1382013
Refinement of ibuprofen at 100K by single-crystal pulsed neutron diffraction
N Shankland, CC Wilson, AJ Florence, PJ Cox
Acta Crystallographica Section C: Crystal Structure Communications 53 (7 …, 1997
1341997
Why we need continuous pharmaceutical manufacturing and how to make it happen
C Badman, CL Cooney, A Florence, K Konstantinov, M Krumme, S Mascia, ...
Journal of pharmaceutical sciences 108 (11), 3521-3523, 2019
1332019
Reversible extrusion and uptake of HCl molecules by crystalline solids involving coordination bond cleavage and formation
G Mínguez Espallargas, L Brammer, J van de Streek, K Shankland, ...
Journal of the American Chemical Society 128 (30), 9584-9585, 2006
1282006
Solving molecular crystal structures from laboratory X-ray powder diffraction data with DASH: the state of the art and challenges
AJ Florence, N Shankland, K Shankland, WIF David, E Pidcock, X Xu, ...
Applied Crystallography 38 (2), 249-259, 2005
1192005
Regulatory perspectives on continuous pharmaceutical manufacturing: moving from theory to practice: September 26-27, 2016, international symposium on the continuous …
MM Nasr, M Krumme, Y Matsuda, BL Trout, C Badman, S Mascia, ...
Journal of pharmaceutical sciences 106 (11), 3199-3206, 2017
1172017
Complex Polymorphic System of Gallic Acid Five Monohydrates, Three Anhydrates, and over 20 Solvates
DE Braun, RM Bhardwaj, AJ Florence, DA Tocher, SL Price
Crystal growth & design 13 (1), 19-23, 2013
1132013
Seeded Crystallization of β-l-Glutamic Acid in a Continuous Oscillatory Baffled Crystallizer
NEB Briggs, U Schacht, V Raval, T McGlone, J Sefcik, AJ Florence
Organic Process Research & Development 19 (12), 1903-1911, 2015
1052015
Direct determination of the temperature dependence of proton transfer in the benzoic acid dimer by single crystal neutron diffraction
CC Wilson, N Shankland, AJ Florence
Chemical physics letters 253 (1-2), 103-107, 1996
1031996
Development of a hot-melt extrusion (HME) process to produce drug loaded Affinisol™ 15LV filaments for fused filament fabrication (FFF) 3D printing
E Prasad, MT Islam, DJ Goodwin, AJ Megarry, GW Halbert, AJ Florence, ...
Additive Manufacturing 29, 100776, 2019
1022019
Characterisation of amorphous and nanocrystalline molecular materials by total scattering
SJL Billinge, T Dykhne, P Juhás, E Božin, R Taylor, AJ Florence, ...
CrystEngComm 12 (5), 1366-1368, 2010
1002010
From discovery to scale-up: α-lipoic acid: nicotinamide co-crystals in a continuous oscillatory baffled crystalliser
L Zhao, V Raval, NEB Briggs, RM Bhardwaj, T McGlone, IDH Oswald, ...
CrystEngComm 16 (26), 5769-5780, 2014
992014
Enabling precision manufacturing of active pharmaceutical ingredients: workflow for seeded cooling continuous crystallisations
CJ Brown, T McGlone, S Yerdelen, V Srirambhatla, F Mabbott, R Gurung, ...
Molecular Systems Design & Engineering 3 (3), 518-549, 2018
982018
Data requirements for the reliable use of atomic pair distribution functions in amorphous pharmaceutical fingerprinting
T Dykhne, R Taylor, A Florence, SJL Billinge
Pharmaceutical research 28, 1041-1048, 2011
942011
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