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Longqin Hu
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Year
Small molecule modulators of K eap1‐N rf2‐ARE pathway as potential preventive and therapeutic agents
S Magesh, Y Chen, L Hu
Medicinal research reviews 32 (4), 687-726, 2012
8622012
Efficient Baylis− Hillman reaction using stoichiometric base catalyst and an aqueous medium
C Yu, B Liu, L Hu
The Journal of Organic Chemistry 66 (16), 5413-5418, 2001
3322001
Discovery of direct inhibitors of Keap1–Nrf2 protein–protein interaction as potential therapeutic and preventive agents
DA Abed, M Goldstein, H Albanyan, H Jin, L Hu
Acta Pharmaceutica Sinica B 5 (4), 285-299, 2015
2912015
Drug delivery: principles and applications
B Wang, L Hu, TJ Siahaan
John Wiley & Sons, 2016
2702016
Design of anticancer prodrugs for reductive activation
Y Chen, L Hu
Medicinal research reviews 29 (1), 29-64, 2009
2682009
Discovery of a small-molecule inhibitor and cellular probe of Keap1–Nrf2 protein–protein interaction
L Hu, S Magesh, L Chen, L Wang, TA Lewis, Y Chen, C Khodier, ...
Bioorganic & medicinal chemistry letters 23 (10), 3039-3043, 2013
2092013
Enzyme-mediated hydrolytic activation of prodrugs
Y Yang, H Aloysius, D Inoyama, Y Chen, L Hu
Acta Pharmaceutica Sinica B 1 (3), 143-159, 2011
1822011
Immunomodulators targeting the PD‐1/PD‐L1 protein‐protein interaction: from antibodies to small molecules
J Yang, L Hu
Medicinal research reviews 39 (1), 265-301, 2019
1512019
Nitroreductase: a prodrug-activating enzyme for cancer gene therapy.
PF Searle, MJ Chen, L Hu, PR Race, AL Lovering, JI Grove, C Guise, ...
Clinical & Experimental Pharmacology & Physiology 31 (11), 2004
1432004
Insects: an underrepresented resource for the discovery of biologically active natural products
L Seabrooks, L Hu
Acta Pharmaceutica Sinica B 7 (4), 409-426, 2017
1422017
Samarium (0) and 1, 1 ‘-dioctyl-4, 4 ‘-bipyridinium dibromide: a novel electron-transfer system for the chemoselective reduction of aromatic nitro groups
C Yu, B Liu, L Hu
The Journal of Organic Chemistry 66 (3), 919-924, 2001
1302001
Successful Baylis− Hillman reaction of acrylamide with aromatic aldehydes
C Yu, L Hu
The Journal of Organic Chemistry 67 (1), 219-223, 2002
1292002
Analysis of multiple metabolites of tocopherols and tocotrienols in mice and humans
Y Zhao, MJ Lee, C Cheung, JH Ju, YK Chen, B Liu, LQ Hu, CS Yang
Journal of agricultural and food chemistry 58 (8), 4844-4852, 2010
1192010
Optimization of fluorescently labeled Nrf2 peptide probes and the development of a fluorescence polarization assay for the discovery of inhibitors of Keap1-Nrf2 interaction
D Inoyama, Y Chen, X Huang, LJ Beamer, ANT Kong, L Hu
Journal of biomolecular screening 17 (4), 435-447, 2012
1092012
Anti-NF-κB and anti-inflammatory activities of synthetic isothiocyanates: effect of chemical structures and cellular signaling
A Prawan, CLL Saw, TO Khor, YS Keum, S Yu, L Hu, AN Kong
Chemico-biological interactions 179 (2-3), 202-211, 2009
992009
Nitroaryl phosphoramides as novel prodrugs for E. coli nitroreductase activation in enzyme prodrug therapy
L Hu, C Yu, Y Jiang, J Han, Z Li, P Browne, PR Race, RJ Knox, PF Searle, ...
Journal of medicinal chemistry 46 (23), 4818-4821, 2003
952003
Kinetic analyses of Keap1–Nrf2 interaction and determination of the minimal Nrf2 peptide sequence required for Keap1 binding using surface plasmon resonance
Y Chen, D Inoyama, ANT Kong, LJ Beamer, L Hu
Chemical biology & drug design 78 (6), 1014-1021, 2011
882011
Design, Synthesis, Evaluation, and Structural Studies of C2-Symmetric Small Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 …
S Basu, J Yang, B Xu, K Magiera-Mularz, L Skalniak, B Musielak, ...
Journal of medicinal chemistry 62 (15), 7250-7263, 2019
852019
Nitrobenzocyclophosphamides as potential prodrugs for bioreductive activation: synthesis, stability, enzymatic reduction, and antiproliferative activity in cell culture
Z Li, J Han, Y Jiang, P Browne, RJ Knox, L Hu
Bioorganic & medicinal chemistry 11 (19), 4171-4178, 2003
842003
Exploiting the drug-activating properties of a novel trypanosomal nitroreductase
BS Hall, X Wu, L Hu, SR Wilkinson
Antimicrobial agents and chemotherapy 54 (3), 1193-1199, 2010
832010
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