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Brian Bacskai
Brian Bacskai
Massachusetts general hospital
Verified email at partners.org
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Cited by
Cited by
Year
Rapid appearance and local toxicity of amyloid-β plaques in a mouse model of Alzheimer’s disease
M Meyer-Luehmann, TL Spires-Jones, C Prada, M Garcia-Alloza, ...
Nature 451 (7179), 720-724, 2008
10902008
Characterization of amyloid deposition in the APPswe/PS1dE9 mouse model of Alzheimer disease
M Garcia-Alloza, EM Robbins, SX Zhang-Nunes, SM Purcell, ...
Neurobiology of disease 24 (3), 516-524, 2006
7432006
Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model
M Garcia‐Alloza, LA Borrelli, A Rozkalne, BT Hyman, BJ Bacskai
Journal of neurochemistry 102 (4), 1095-1104, 2007
7252007
Synchronous hyperactivity and intercellular calcium waves in astrocytes in Alzheimer mice
KV Kuchibhotla, CR Lattarulo, BT Hyman, BJ Bacskai
Science 323 (5918), 1211-1215, 2009
6822009
Spatially Resolved Dynamics of cAMP and Protein Kinase A Subunits in Aplysia Sensory Neurons
BJ Bacskai, B Hochner, M Mahaut-Smith, SR Adams, BK Kaang, ...
Science 260 (5105), 222-226, 1993
6561993
Aβ plaques lead to aberrant regulation of calcium homeostasis in vivo resulting in structural and functional disruption of neuronal networks
KV Kuchibhotla, ST Goldman, CR Lattarulo, HY Wu, BT Hyman, ...
Neuron 59 (2), 214-225, 2008
6332008
Imaging of amyloid-β deposits in brains of living mice permits direct observation of clearance of plaques with immunotherapy
BJ Bacskai, ST Kajdasz, RH Christie, C Carter, D Games, P Seubert, ...
Nature medicine 7 (3), 369-372, 2001
6122001
Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy
TL Spires, M Meyer-Luehmann, EA Stern, PJ McLean, J Skoch, ...
Journal of Neuroscience 25 (31), 7278-7287, 2005
6032005
Amyotrophic lateral sclerosis-associated SOD1 mutant proteins bind and aggregate with Bcl-2 in spinal cord mitochondria
P Pasinelli, ME Belford, N Lennon, BJ Bacskai, BT Hyman, D Trotti, ...
Neuron 43 (1), 19-30, 2004
5992004
Caspase activation precedes and leads to tangles
A De Calignon, LM Fox, R Pitstick, GA Carlson, BJ Bacskai, ...
Nature 464 (7292), 1201-1204, 2010
5842010
Reversible memory loss in a mouse transgenic model of Alzheimer's disease
LA Kotilinek, B Bacskai, M Westerman, T Kawarabayashi, L Younkin, ...
Journal of Neuroscience 22 (15), 6331-6335, 2002
5342002
A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain
CA Mathis, BJ Bacskai, ST Kajdasz, ME McLellan, MP Frosch, BT Hyman, ...
Bioorganic & medicinal chemistry letters 12 (3), 295-298, 2002
4542002
Dysferlin interacts with annexins A1 and A2 and mediates sarcolemmal wound-healing
NJ Lennon, A Kho, BJ Bacskai, SL Perlmutter, BT Hyman, RH Brown
Journal of Biological Chemistry 278 (50), 50466-50473, 2003
4282003
Imaging Aβ plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative
WE Klunk, BJ Bacskai, CA Mathis, ST Kajdasz, ME McLellan, MP Frosch, ...
Journal of Neuropathology & Experimental Neurology 61 (9), 797-805, 2002
4182002
Design, synthesis, and testing of difluoroboron-derivatized curcumins as near-infrared probes for in vivo detection of amyloid-β deposits
C Ran, X Xu, SB Raymond, BJ Ferrara, K Neal, BJ Bacskai, Z Medarova, ...
Journal of the American Chemical Society 131 (42), 15257-15261, 2009
4092009
Non-Fc-mediated mechanisms are involved in clearance of amyloid-β in vivo by immunotherapy
BJ Bacskai, ST Kajdasz, ME McLellan, D Games, P Seubert, D Schenk, ...
Journal of Neuroscience 22 (18), 7873-7878, 2002
3952002
Amyloid β induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation
HY Wu, E Hudry, T Hashimoto, K Kuchibhotla, A Rozkalne, Z Fan, ...
Journal of Neuroscience 30 (7), 2636-2649, 2010
3742010
Molecular imaging with Pittsburgh Compound B confirmed at autopsy: a case report
BJ Bacskai, MP Frosch, SH Freeman, SB Raymond, JC Augustinack, ...
Archives of neurology 64 (3), 431-434, 2007
3562007
In vivo optical imaging of amyloid aggregates in brain: design of fluorescent markers
EE Nesterov, J Skoch, BT Hyman, WE Klunk, BJ Bacskai, TM Swager
Angewandte Chemie International Edition 44 (34), 5452-5456, 2005
3532005
Four-dimensional multiphoton imaging of brain entry, amyloid binding, and clearance of an amyloid-β ligand in transgenic mice
BJ Bacskai, GA Hickey, J Skoch, ST Kajdasz, Y Wang, G Huang, ...
Proceedings of the National Academy of Sciences 100 (21), 12462-12467, 2003
3472003
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