David Sulzer
David Sulzer
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
Impaired degradation of mutant α-synuclein by chaperone-mediated autophagy
AM Cuervo, L Stefanis, R Fredenburg, PT Lansbury, D Sulzer
Science, 2004
Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
A Abeliovich, Y Schmitz, I Fariņas, D Choi-Lundberg, WH Ho, PE Castillo, ...
Neuron 25 (1), 239-252, 2000
Mechanisms of neurotransmitter release by amphetamines: a review
D Sulzer, MS Sonders, NW Poulsen, A Galli
Progress in neurobiology 75 (6), 406-433, 2005
Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits
G Tang, K Gudsnuk, SH Kuo, ML Cotrina, G Rosoklija, A Sosunov, ...
Neuron 83 (5), 1131-1143, 2014
Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease
M Martinez-Vicente, Z Talloczy, E Wong, G Tang, H Koga, S Kaushik, ...
Nature neuroscience 13 (5), 567-576, 2010
Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport
D Sulzer, TK Chen, YY Lau, H Kristensen, S Rayport, A Ewing
Journal of Neuroscience 15 (5), 4102-4108, 1995
Expression of A53T mutant but not wild-type α-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and …
L Stefanis, KE Larsen, HJ Rideout, D Sulzer, LA Greene
Journal of Neuroscience 21 (24), 9549-9560, 2001
Dopamine-modified α-synuclein blocks chaperone-mediated autophagy
M Martinez-Vicente, Z Talloczy, S Kaushik, AC Massey, J Mazzulli, ...
The Journal of clinical investigation 118 (2), 777-788, 2008
Resistance of α-synuclein null mice to the parkinsonian neurotoxin MPTP
W Dauer, N Kholodilov, M Vila, AC Trillat, R Goodchild, KE Larsen, ...
Proceedings of the National Academy of Sciences 99 (22), 14524-14529, 2002
Multiple hit hypotheses for dopamine neuron loss in Parkinson's disease
D Sulzer
Trends in neurosciences 30 (5), 244-250, 2007
The identification of vesicular glutamate transporter 3 suggests novel modes of signaling by glutamate
RT Fremeau, J Burman, T Qureshi, CH Tran, J Proctor, J Johnson, ...
Proceedings of the National Academy of Sciences 99 (22), 14488-14493, 2002
Interplay of LRRK2 with chaperone-mediated autophagy
SJ Orenstein, SH Kuo, I Tasset, E Arias, H Koga, I Fernandez-Carasa, ...
Nature neuroscience 16 (4), 394-406, 2013
Interplay between cytosolic dopamine, calcium, and α-synuclein causes selective death of substantia nigra neurons
EV Mosharov, KE Larsen, E Kanter, KA Phillips, K Wilson, Y Schmitz, ...
Neuron 62 (2), 218-229, 2009
How addictive drugs disrupt presynaptic dopamine neurotransmission
D Sulzer
Neuron 69 (4), 628-649, 2011
Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress
JF Cubells, S Rayport, G Rajendran, D Sulzer
Journal of Neuroscience 14 (4), 2260-2271, 1994
Amphetamine and other psychostimulants reduce pH gradients in midbrain dopaminergic neurons and chromaffin granules: a mechanism of action
D Sulzer, S Rayport
Neuron 5 (6), 797-808, 1990
T cells from patients with Parkinson’s disease recognize α-synuclein peptides
D Sulzer, RN Alcalay, F Garretti, L Cote, E Kanter, J Agin-Liebes, C Liong, ...
Nature 546 (7660), 656-661, 2017
α-Synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis
KE Larsen, Y Schmitz, MD Troyer, E Mosharov, P Dietrich, AZ Quazi, ...
Journal of Neuroscience 26 (46), 11915-11922, 2006
Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles
D Sulzer, J Bogulavsky, KE Larsen, G Behr, E Karatekin, MH Kleinman, ...
Proceedings of the National Academy of Sciences 97 (22), 11869-11874, 2000
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