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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets AK Witkiewicz, EA McMillan, U Balaji, GH Baek, WC Lin, J Mansour, ... Nature communications 6 (1), 1-11, 2015 | 1114 | 2015 |
Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression DG Burbee, E Forgacs, S Zöchbauer-Müller, L Shivakumar, K Fong, ... Journal of the National Cancer Institute 93 (9), 691-699, 2001 | 1077 | 2001 |
Absence of cancer–associated changes in human fibroblasts immortalized with telomerase CP Morales, SE Holt, M Ouellette, KJ Kaur, Y Yan, KS Wilson, MA White, ... Nature genetics 21 (1), 115-118, 1999 | 1027 | 1999 |
Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav J Han, K Luby-Phelps, B Das, X Shu, Y Xia, RD Mosteller, UM Krishna, ... Science 279 (5350), 558-560, 1998 | 1025 | 1998 |
Meta-and orthogonal integration of influenza “OMICs” data defines a role for UBR4 in virus budding S Tripathi, MO Pohl, Y Zhou, A Rodriguez-Frandsen, G Wang, DA Stein, ... Cell host & microbe 18 (6), 723-735, 2015 | 926 | 2015 |
Multiple Ras functions can contribute to mammalian cell transformation MA White, C Nicolette, A Minden, A Polverino, L Van Aelst, M Karin, ... Cell 80 (4), 533-541, 1995 | 832 | 1995 |
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation RC Wang, Y Wei, Z An, Z Zou, G Xiao, G Bhagat, M White, J Reichelt, ... Science 338 (6109), 956-959, 2012 | 812 | 2012 |
RNA interference in mammalian cells by chemically-modified RNA DA Braasch, S Jensen, Y Liu, K Kaur, K Arar, MA White, DR Corey Biochemistry 42 (26), 7967-7975, 2003 | 811 | 2003 |
Functional requirement of p23 and Hsp90 in telomerase complexes SE Holt, DL Aisner, J Baur, VM Tesmer, M Dy, M Ouellette, JB Trager, ... Genes & development 13 (7), 817-826, 1999 | 756 | 1999 |
Protein interaction mapping: a Drosophila case study E Formstecher, S Aresta, V Collura, A Hamburger, A Meil, A Trehin, ... Genome research 15 (3), 376-384, 2005 | 679 | 2005 |
Biochemical and genetic analysis of the yeast proteome with a movable ORF collection DM Gelperin, MA White, ML Wilkinson, Y Kon, LA Kung, KJ Wise, ... Genes & development 19 (23), 2816-2826, 2005 | 611 | 2005 |
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation L Shivakumar, J Minna, T Sakamaki, R Pestell, MA White Molecular and cellular biology 22 (12), 4309-4318, 2002 | 609 | 2002 |
Synthetic lethal screen identification of chemosensitizer loci in cancer cells AW Whitehurst, BO Bodemann, J Cardenas, D Ferguson, L Girard, ... Nature 446 (7137), 815-819, 2007 | 586 | 2007 |
The exocyst is a Ral effector complex S Moskalenko, DO Henry, C Rosse, G Mirey, JH Camonis, MA White Nature cell biology 4 (1), 66-72, 2002 | 515 | 2002 |
Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS T Joneson, MA White, MH Wigler, D Bar-Sagi Science 271 (5250), 810-812, 1996 | 486 | 1996 |
Degradation of AMPK by a cancer-specific ubiquitin ligase CT Pineda, S Ramanathan, KF Tacer, JL Weon, MB Potts, YH Ou, ... Cell 160 (4), 715-728, 2015 | 480 | 2015 |
RalB GTPase-mediated activation of the IκB family kinase TBK1 couples innate immune signaling to tumor cell survival Y Chien, S Kim, R Bumeister, YM Loo, SW Kwon, CL Johnson, ... Cell 127 (1), 157-170, 2006 | 453 | 2006 |
Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation R Khosravi-Far, MA White, JK Westwick, PA Solski, ... Molecular and cellular biology 16 (7), 3923-3933, 1996 | 441 | 1996 |
A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation MJ Robinson, SA Stippec, E Goldsmith, MA White, MH Cobb Current biology 8 (21), 1141-1152, 1998 | 381 | 1998 |