Gilles Guillemin

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nady braidyUniversity of New South WalesVerified email at unsw.edu.au
Chai K. LimSenior Research Fellow, Faculty of Medicine and Health Sciences, Macquarie UniversityVerified email at mq.edu.au
Benjamin HengMacquarie universityVerified email at mq.edu.au
Perminder SachdevUniversity of New South WalesVerified email at unsw.edu.au
Tailoi Chan-LingProfessor of Neurobiology & Visual Science, The University of SydneyVerified email at anatomy.usyd.edu.au
Christiane A. OpitzDivision Head "Metabolic Crosstalk in Cancer", German Cancer Research Center (DKFZ)Verified email at dkfz.de
Sophie ErhardtProfessor in Experimental PsychiatryVerified email at ki.se
Philippe FroguelImperial College London and INSERM-Lille UnivVerified email at imperial.ac.uk
Yahya Al-FarsiProfessor of Epidemiology & Public Health, Sultan Qaboos UniversityVerified email at squ.edu.om
Lucette A. CysiqueDepartment of Psychology, The University of New South Wales, Sydney, AustraliaVerified email at unsw.edu.au
Brett NeilanThe University of Newcastle, AustraliaVerified email at newcastle.edu.au
Andrew F. HillDeputy Vice-Chancellor Research & Impact, Victoria UniversityVerified email at vu.edu.au
Michelle M. GehringerResearcher, Technical University of Kaiserslautern, GermanyVerified email at rhrk.uni-kl.de
Carlos BarciaUniversitat Autònoma de BarcelonaVerified email at uab.es
John ZaundersSenior Scientist, St Vincent's Hospital, Sydney Verified email at amr.org.au
Simon P JonesResearch Fellow, St Vincent's Clinical School, The University of New South WalesVerified email at unsw.edu.au
Wendy JessupProfessor, ANZAC Research Institute, University of SydneyVerified email at sydney.edu.au
Dominique LaurentProfesseur, Université de Cergy PontoiseVerified email at u-cergy.fr
Georges GrauProfessor of Pathology, The University of SydneyVerified email at med.usyd.edu.au
Anandwardhan HardikarWestern Sydney University, Campbelltown CampusVerified email at westernsydney.edu.au

Gilles Guillemin

Macquarie University

Verified email at mq.edu.au - Homepage

Tryptophan metabolism Kynurenine pathway neuroinflammation neurodegenerative diseases


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An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor CA Opitz, UM Litzenburger, F Sahm, M Ott, I Tritschler, S Trump, ... Nature 478 (7368), 197-203, 2011	1842	2011
Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification GJ Guillemin, BJ Brew Journal of Leucocyte Biology 75 (3), 388-397, 2004	690	2004
Kynurenine pathway metabolites in humans: disease and healthy states Y Chen, GJ Guillemin International journal of tryptophan research 2, IJTR. S2097, 2009	678	2009
Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats N Braidy, GJ Guillemin, H Mansour, T Chan-Ling, A Poljak, R Grant PloS one 6 (4), e19194, 2011	673	2011
Aryl hydrocarbon receptor control of a disease tolerance defence pathway A Bessede, M Gargaro, MT Pallotta, D Matino, G Servillo, C Brunacci, ... Nature 511 (7508), 184-190, 2014	654	2014
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: evidence for an immune-modulated glutamatergic … J Steiner, M Walter, T Gos, GJ Guillemin, HG Bernstein, Z Sarnyai, ... Journal of neuroinflammation 8, 1-9, 2011	596	2011
Age-Associated Changes In Oxidative Stress and NAD⁺ Metabolism In Human Tissue H Massudi, R Grant, N Braidy, J Guest, B Farnsworth, GJ Guillemin Public Library of Science 7 (7), e42357, 2012	586	2012
Kynurenine pathway metabolism in human astrocytes: a paradox for neuronal protection GJ Guillemin, SJ Kerr, GA Smythe, DG Smith, V Kapoor, PJ Armati, ... Journal of neurochemistry 78 (4), 842-853, 2001	574	2001
Expression of indoleamine 2, 3‐dioxygenase and production of quinolinic acid by human microglia, astrocytes, and neurons GJ Guillemin, G Smythe, O Takikawa, BJ Brew Glia 49 (1), 15-23, 2005	550	2005
Quinolinic acid, the inescapable neurotoxin GJ Guillemin The FEBS journal 279 (8), 1356-1365, 2012	548	2012
The role of reactive oxygen species in the pathogenesis of Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease: a mini review S Manoharan, GJ Guillemin, RS Abiramasundari, MM Essa, M Akbar, ... Oxidative medicine and cellular longevity 2016, 2016	506	2016
Indoleamine 2, 3 dioxygenase and quinolinic acid immunoreactivity in Alzheimer's disease hippocampus GJ Guillemin, BJ Brew, CE Noonan, O Takikawa, KM Cullen Neuropathology and applied neurobiology 31 (4), 395-404, 2005	354	2005
Characterization of the kynurenine pathway in human neurons GJ Guillemin, KM Cullen, CK Lim, GA Smythe, B Garner, V Kapoor, ... Journal of Neuroscience 27 (47), 12884-12892, 2007	347	2007
Connecting inflammation with glutamate agonism in suicidality S Erhardt, CK Lim, KR Linderholm, S Janelidze, D Lindqvist, ... Neuropsychopharmacology 38 (5), 743-752, 2013	343	2013
Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases MD Lovelace, B Varney, G Sundaram, MJ Lennon, CK Lim, K Jacobs, ... Neuropharmacology 112, 373-388, 2017	332	2017
Neuroprotective effect of natural products against Alzheimer’s disease MM Essa, RK Vijayan, G Castellano-Gonzalez, MA Memon, N Braidy, ... Neurochemical research 37, 1829-1842, 2012	312	2012
A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality C Bay-Richter, KR Linderholm, CK Lim, M Samuelsson, ... Brain, behavior, and immunity 43, 110-117, 2015	285	2015
Expression of the kynurenine pathway enzymes in human microglia and macrophages GJ Guillemin, DG Smith, GA Smythe, PJ Armati, GJ Brew Developments in tryptophan and serotonin metabolism, 105-112, 2003	251	2003
Mechanism for quinolinic acid cytotoxicity in human astrocytes and neurons N Braidy, R Grant, S Adams, BJ Brew, GJ Guillemin Neurotoxicity research 16, 77-86, 2009	242	2009
The kynurenine pathway is activated in human obesity and shifted toward kynurenine monooxygenase activation M Favennec, B Hennart, R Caiazzo, A Leloire, L Yengo, M Verbanck, ... Obesity 23 (10), 2066-2074, 2015	235	2015

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