| Evolutionarily conserved pathways of energetic connectivity in protein families SW Lockless, R Ranganathan Science 286 (5438), 295-299, 1999 | 1639 | 1999 |
| Evolutionarily conserved networks of residues mediate allosteric communication in proteins GM Süel, SW Lockless, MA Wall, R Ranganathan Nature structural biology 10 (1), 59-69, 2003 | 994 | 2003 |
| Structural and functional analysis of the mitotic rotamase Pin1 suggests substrate recognition is phosphorylation dependent R Ranganathan, KP Lu, T Hunter, JP Noel Cell 89 (6), 875-886, 1997 | 881 | 1997 |
| Protein sectors: evolutionary units of three-dimensional structure N Halabi, O Rivoire, S Leibler, R Ranganathan Cell 138 (4), 774-786, 2009 | 831 | 2009 |
| The spatial architecture of protein function and adaptation RN McLaughlin Jr, FJ Poelwijk, A Raman, WS Gosal, R Ranganathan Nature 491 (7422), 138-142, 2012 | 527 | 2012 |
| Evolutionary information for specifying a protein fold M Socolich, SW Lockless, WP Russ, H Lee, KH Gardner, R Ranganathan Nature 437 (7058), 512-518, 2005 | 517 | 2005 |
| The structural basis for red fluorescence in the tetrameric GFP homolog DsRed MA Wall, M Socolich, R Ranganathan Nature structural biology 7 (12), 1133-1138, 2000 | 469 | 2000 |
| Structural determinants of allosteric ligand activation in RXR heterodimers AI Shulman, C Larson, DJ Mangelsdorf, R Ranganathan Cell 116 (3), 417-429, 2004 | 402 | 2004 |
| Surface sites for engineering allosteric control in proteins J Lee, M Natarajan, VC Nashine, M Socolich, T Vo, WP Russ, ... Science 322 (5900), 438-442, 2008 | 398 | 2008 |
| Arrestin function in inactivation of G protein-coupled receptor rhodopsin in vivo PJ Dolph, R Ranganathan, NJ Colley, RW Hardy, M Socolich, CS Zuker Science 260 (5116), 1910-1916, 1993 | 393 | 1993 |
| Hot spots for allosteric regulation on protein surfaces KA Reynolds, RN McLaughlin, R Ranganathan Cell 147 (7), 1564-1575, 2011 | 390 | 2011 |
| Spatial localization of the K+ channel selectivity filter by mutant cycle–based structure analysis R Ranganathan, JH Lewis, R MacKinnon Neuron 16 (1), 131-139, 1996 | 375 | 1996 |
| Natural-like function in artificial WW domains WP Russ, DM Lowery, P Mishra, MB Yaffe, R Ranganathan Nature 437 (7058), 579-583, 2005 | 340 | 2005 |
| Evolvability as a function of purifying selection in TEM-1 β-lactamase MA Stiffler, DR Hekstra, R Ranganathan Cell 160 (5), 882-892, 2015 | 322 | 2015 |
| Photoreceptor deactivation and retinal degeneration mediated by a photoreceptor-specific protein kinase C DP Smith, R Ranganathan, RW Hardy, J Marx, T Tsuchida, CS Zuker Science 254 (5037), 1478-1484, 1991 | 283 | 1991 |
| A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila A Kiselev, M Socolich, J Vinós, RW Hardy, CS Zuker, R Ranganathan Neuron 28 (1), 139-152, 2000 | 276 | 2000 |
| An evolution-based model for designing chorismate mutase enzymes WP Russ, M Figliuzzi, C Stocker, P Barrat-Charlaix, M Socolich, P Kast, ... Science 369 (6502), 440-445, 2020 | 274 | 2020 |
| A global analysis of cross-talk in a mammalian cellular signalling network M Natarajan, KM Lin, RC Hsueh, PC Sternweis, R Ranganathan Nature cell biology 8 (6), 571-580, 2006 | 274 | 2006 |
| PDZ domain proteins: scaffolds for signaling complexes R Ranganathan, EM Ross Current Biology 7 (12), R770-R773, 1997 | 246 | 1997 |
| Signal transduction in Drosophila photoreceptors R Ranganathan, DM Malicki, CS Zuker Annual review of neuroscience 18 (1), 283-317, 1995 | 245 | 1995 |
