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Vasan Sambandamurthy
Vasan Sambandamurthy
Bugworks Research Private Limited
Verified email at bugworksresearch.com - Homepage
Title
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Cited by
Year
Specialized transduction: an efficient method for generating marked and unmarked targeted gene disruptions in Mycobacterium tuberculosis, M. bovis BCG and M. smegmatis
S Bardarov, S Bardarov Jr, MS Pavelka Jr, V Sambandamurthy, M Larsen, ...
Microbiology 148 (10), 3007-3017, 2002
7172002
A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis
VK Sambandamurthy, X Wang, B Chen, RG Russell, S Derrick, FM Collins, ...
Nature medicine 8 (10), 1171-1174, 2002
4432002
Survival perspectives from the world's most successful pathogen, Mycobacterium tuberculosis
SM Hingley-Wilson, VK Sambandamurthy, WR Jacobs Jr
Nature immunology 4 (10), 949-955, 2003
2662003
Mycobacterium tuberculosis ΔRD1 ΔpanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis
VK Sambandamurthy, SC Derrick, T Hsu, B Chen, MH Larsen, ...
Vaccine 24 (37-39), 6309-6320, 2006
2222006
The natural product cyclomarin kills Mycobacterium tuberculosis by targeting the ClpC1 subunit of the caseinolytic protease
EK Schmitt, M Riwanto, V Sambandamurthy, S Roggo, C Miault, ...
Angewandte Chemie International Edition 26 (50), 5889-5891, 2011
2062011
Long-term protection against tuberculosis following vaccination with a severely attenuated double lysine and pantothenate auxotroph of Mycobacterium tuberculosis
VK Sambandamurthy, SC Derrick, KV Jalapathy, B Chen, RG Russell, ...
Infection and immunity 73 (2), 1196-1203, 2005
1772005
Protection Elicited by a Double Leucine and Pantothenate Auxotroph of Mycobacterium tuberculosis in Guinea Pigs
SL Sampson, CC Dascher, VK Sambandamurthy, RG Russell, ...
Infection and immunity 72 (5), 3031-3037, 2004
1712004
Azaindoles: Noncovalent DprE1 Inhibitors from Scaffold Morphing Efforts, Kill Mycobacterium tuberculosis and Are Efficacious in Vivo
PS Shirude, R Shandil, C Sadler, M Naik, V Hosagrahara, S Hameed, ...
Journal of Medicinal Chemistry 56 (23), 9701-9708, 2013
1612013
Efficacy and safety of live attenuated persistent and rapidly cleared Mycobacterium tuberculosis vaccine candidates in non-human primates
MH Larsen, K Biermann, B Chen, T Hsu, VK Sambandamurthy, ...
Vaccine 27 (34), 4709-4717, 2009
1232009
Bactericidal activity and mechanism of action of AZD5847, a novel oxazolidinone for treatment of tuberculosis
V Balasubramanian, S Solapure, H Iyer, A Ghosh, S Sharma, P Kaur, ...
Antimicrobial agents and chemotherapy 58 (1), 495-502, 2014
1202014
Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis
M Kurabachew, SHJ Lu, P Krastel, EK Schmitt, BL Suresh, A Goh, ...
Journal of antimicrobial chemotherapy 62 (4), 713-719, 2008
1152008
Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis
SJ Tantry, SD Markad, V Shinde, J Bhat, G Balakrishnan, AK Gupta, ...
Journal of medicinal chemistry 60 (4), 1379-1399, 2017
1112017
Methyl-thiazoles: a novel mode of inhibition with the potential to develop novel inhibitors targeting InhA in Mycobacterium tuberculosis
PS Shirude, P Madhavapeddi, M Naik, K Murugan, V Shinde, ...
Journal of Medicinal Chemistry 56 (21), 8533-8542, 2013
1062013
Multi-scale surface topography to minimize adherence and viability of nosocomial drug-resistant bacteria
J Hasan, S Jain, R Padmarajan, S Purighalla, VK Sambandamurthy, ...
Materials & design 140, 332-344, 2018
1002018
Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity
M Panda, S Ramachandran, V Ramachandran, PS Shirude, ...
Journal of medicinal chemistry 57 (11), 4761-4771, 2014
992014
4-aminoquinolone piperidine amides: noncovalent inhibitors of DprE1 with long residence time and potent antimycobacterial activity
M Naik, V Humnabadkar, SJ Tantry, M Panda, A Narayan, S Guptha, ...
Journal of medicinal chemistry 57 (12), 5419-5434, 2014
952014
Lead optimization of 1, 4-azaindoles as antimycobacterial agents
PS Shirude, RK Shandil, MR Manjunatha, C Sadler, M Panda, V Panduga, ...
Journal of medicinal chemistry 57 (13), 5728-5737, 2014
942014
Aminopyrazinamides: Novel and Specific GyrB Inhibitors that Kill Replicating and Nonreplicating Mycobacterium tuberculosis
PS Shirude, P Madhavapeddi, JA Tucker, K Murugan, V Patil, ...
ACS chemical biology 8 (3), 519-523, 2013
902013
Live attenuated mutants of Mycobacterium tuberculosis as candidate vaccines against tuberculosis
VK Sambandamurthy, WR Jacobs Jr
Microbes and infection 7 (5-6), 955-961, 2005
822005
In Vitro and In Vivo Activities of Three Oxazolidinones against Nonreplicating Mycobacterium tuberculosis
M Zhang, C Sala, N Dhar, A Vocat, VK Sambandamurthy, S Sharma, ...
Antimicrobial agents and chemotherapy 58 (6), 3217-3223, 2014
712014
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