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Rajat M Gupta
Rajat M Gupta
Brigham and Women's Hospital/Harvard Medical School
Verified email at bwh.harvard.edu - Homepage
Title
Cited by
Cited by
Year
A TALEN genome-editing system for generating human stem cell-based disease models
Q Ding, YK Lee, EAK Schaefer, DT Peters, A Veres, K Kim, ...
Cell stem cell 12 (2), 238-251, 2013
7042013
Expanding the genetic editing tool kit: ZFNs, TALENs, and CRISPR-Cas9
RM Gupta, K Musunuru
The Journal of clinical investigation 124 (10), 4154-4161, 2014
6222014
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
Nature 595 (7865), 107-113, 2021
5962021
A Genetic Variant Associated with Five Vascular Diseases Is a Distal Regulator of Endothelin-1 Gene Expression
RM Gupta, J Hadaya, A Trehan, SM Zekavat, C Roselli, D Klarin, ...
Cell 170 (3), 522-533. e15, 2017
4022017
Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule
I Gotsman, N Grabie, R Gupta, R Dacosta, M MacConmara, J Lederer, ...
Circulation 114 (19), 2047-2055, 2006
2672006
Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis
Y Morita, J Yang, R Gupta, K Shimizu, EA Shelden, J Endres, JJ Mulé, ...
The Journal of clinical investigation 107 (10), 1275-1284, 2001
2612001
Single Cell Analysis of the Normal Mouse Aorta Reveals Functionally Distinct Endothelial Cell Populations
AS Kalluri, SK Vellarikkal, ER Edelman, L Nguyen, A Subramanian, ...
Circulation, 2019
2332019
Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants
KG Aragam, T Jiang, A Goel, S Kanoni, BN Wolford, DS Atri, EM Weeks, ...
Nature Genetics 54 (12), 1803-1815, 2022
2052022
Induced pluripotent stem cells for cardiovascular disease modeling and precision medicine: a scientific statement from the American Heart Association
K Musunuru, F Sheikh, RM Gupta, SR Houser, KO Maher, DJ Milan, ...
Circulation: Genomic and Precision Medicine 11 (1), e000043, 2018
2012018
Effector function of resting T cells: activation of synovial fibroblasts
Y Yamamura, R Gupta, Y Morita, X He, R Pai, J Endres, A Freiberg, ...
The Journal of Immunology 166 (4), 2270-2275, 2001
1542001
Leveraging polygenic enrichments of gene features to predict genes underlying complex traits and diseases
EM Weeks, JC Ulirsch, NY Cheng, BL Trippe, RS Fine, J Miao, ...
Nature genetics 55 (8), 1267-1276, 2023
1282023
Deep learning enables genetic analysis of the human thoracic aorta
JP Pirruccello, MD Chaffin, EL Chou, SJ Fleming, H Lin, M Nekoui, ...
Nature genetics 54 (1), 40-51, 2022
1132022
Myocardial Infarction–Associated SNP at 6p24 Interferes With MEF2 Binding and Associates With PHACTR1 Expression Levels in Human Coronary Arteries
M Beaudoin, RM Gupta, HH Won, KS Lo, R Do, CA Henderson, ...
Arteriosclerosis, thrombosis, and vascular biology 35 (6), 1472-1479, 2015
1012015
Integrative analysis of PRKAG2 cardiomyopathy iPS and microtissue models identifies AMPK as a regulator of metabolism, survival, and fibrosis
JT Hinson, A Chopra, A Lowe, CC Sheng, RM Gupta, R Kuppusamy, ...
Cell reports 17 (12), 3292-3304, 2016
932016
Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-α on cytokine-activated T cells
CN Tran, SK Lundy, PT White, JL Endres, CD Motyl, R Gupta, CM Wilke, ...
The American journal of pathology 171 (5), 1588-1598, 2007
922007
Enhancing literacy in cardiovascular genetics: a scientific statement from the American Heart Association
S Mital, K Musunuru, V Garg, MW Russell, DE Lanfear, RM Gupta, ...
Circulation: Cardiovascular Genetics 9 (5), 448-467, 2016
712016
The influence of the regulatory T lymphocytes on atherosclerosis
I Gotsman, R Gupta, AH Lichtman
Arteriosclerosis, thrombosis, and vascular biology 27 (12), 2493-2495, 2007
712007
Genome-edited human pluripotent stem cell–derived macrophages as a model of reverse cholesterol transport—brief report
RM Gupta, TB Meissner, CA Cowan, K Musunuru
Arteriosclerosis, thrombosis, and vascular biology 36 (1), 15-18, 2016
452016
A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
bioRxiv, 2021
392021
Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica
R Gupta, K Ejebe, J Butler, G Lettre, H Lyon, C Guiducci, R Wilks, ...
Human genetics 128 (5), 557-561, 2010
242010
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