| A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice Y Yang, L Wang, P Bell, D McMenamin, Z He, J White, H Yu, C Xu, ... Nature biotechnology 34 (3), 334-338, 2016 | 620 | 2016 |
| Calcium phosphate nanoparticles with an asymmetric lipid bilayer coating for siRNA delivery to the tumor J Li, Y Yang, L Huang Journal of controlled release 158 (1), 108-114, 2012 | 344 | 2012 |
| Systemic delivery of modified mRNA encoding herpes simplex virus 1 thymidine kinase for targeted cancer gene therapy Y Wang, H Su, Y Yang, Y Hu, L Zhang, P Blancafort, L Huang Molecular Therapy 21 (2), 358-367, 2013 | 315 | 2013 |
| Systemic delivery of siRNA via LCP nanoparticle efficiently inhibits lung metastasis Y Yang, J Li, F Liu, L Huang Molecular Therapy 20 (3), 609-615, 2012 | 136 | 2012 |
| SKLB1002, a Novel Potent Inhibitor of VEGF Receptor 2 Signaling, Inhibits Angiogenesis and Tumor Growth In Vivo S Zhang, Z Cao, H Tian, G Shen, Y Ma, H Xie, Y Liu, C Zhao, S Deng, ... Clinical cancer research 17 (13), 4439-4450, 2011 | 104 | 2011 |
| Human adipose-derived mesenchymal stem cell-secreted CXCL1 and CXCL8 facilitate breast tumor growth by promoting angiogenesis Y Wang, J Liu, Q Jiang, J Deng, F Xu, X Chen, F Cheng, Y Zhang, Y Yao, ... Stem Cells 35 (9), 2060-2070, 2017 | 102 | 2017 |
| SARI inhibits angiogenesis and tumour growth of human colon cancer through directly targeting ceruloplasmin L Dai, X Cui, X Zhang, L Cheng, Y Liu, Y Yang, P Fan, Q Wang, Y Lin, ... Nature communications 7, 2016 | 102 | 2016 |
| Nanoparticle delivery of pooled siRNA for effective treatment of non-small cell lung caner Y Yang, Y Hu, Y Wang, J Li, F Liu, L Huang Molecular pharmaceutics 9 (8), 2280-2289, 2012 | 98 | 2012 |
| IL-35 decelerates the inflammatory process by regulating inflammatory cytokine secretion and M1/M2 macrophage ratio in psoriasis J Zhang, Y Lin, C Li, X Zhang, L Cheng, L Dai, Y Wang, F Wang, G Shi, ... The Journal of Immunology 197 (6), 2131-2144, 2016 | 96 | 2016 |
| Modulating the tumor microenvironment via oncolytic viruses and CSF-1R inhibition synergistically enhances anti-PD-1 immunotherapy G Shi, Q Yang, Y Zhang, Q Jiang, Y Lin, S Yang, H Wang, L Cheng, ... Molecular Therapy 27 (1), 244-260, 2019 | 75 | 2019 |
| CRISPR/Cas9-mediated in vivo gene targeting corrects hemostasis in newborn and adult factor IX–knockout mice L Wang, Y Yang, CA Breton, J White, J Zhang, Y Che, A Saveliev, ... Blood, The Journal of the American Society of Hematology 133 (26), 2745-2752, 2019 | 74 | 2019 |
| IL‐35 recombinant protein reverses inflammatory bowel disease and psoriasis through regulation of inflammatory cytokines and immune cells Y Wang, Y Mao, J Zhang, G Shi, L Cheng, Y Lin, Y Li, X Zhang, Y Zhang, ... Journal of cellular and molecular medicine 22 (2), 1014-1025, 2018 | 72 | 2018 |
| Progress in the treatment of infantile hemangioma ZY Chen, QN Wang, YH Zhu, LY Zhou, T Xu, ZY He, Y Yang Annals of translational medicine 7 (22), 2019 | 62 | 2019 |
| Therapeutic upregulation of Class A scavenger receptor member 5 inhibits tumor growth and metastasis N Yan, S Zhang, Y Yang, L Cheng, C Li, L Dai, L Dai, X Zhang, P Fan, ... Cancer science 103 (9), 1631-1639, 2012 | 60 | 2012 |
| Vector‐based miR‐15a/16‐1 plasmid inhibits colon cancer growth in vivo L Dai, W Wang, S Zhang, Q Jiang, R Wang, L Dai, L Cheng, Y Yang, ... Cell biology international 36 (8), 765-770, 2012 | 59 | 2012 |
| A mutation-independent CRISPR-Cas9–mediated gene targeting approach to treat a murine model of ornithine transcarbamylase deficiency L Wang, Y Yang, C Breton, P Bell, M Li, J Zhang, Y Che, A Saveliev, Z He, ... Science Advances 6 (7), eaax5701, 2020 | 58 | 2020 |
| Non-viral and viral delivery systems for CRISPR-Cas9 technology in the biomedical field ZY He, K Men, Z Qin, Y Yang, T Xu, YQ Wei Science China Life Sciences 60, 458-467, 2017 | 54 | 2017 |
| CRISPR/Cas9-mediated correction of human genetic disease K Men, X Duan, Z He, Y Yang, S Yao, Y Wei Science China Life Sciences 60, 447-457, 2017 | 49 | 2017 |
| Applications of genome editing technology in animal disease modeling and gene therapy Q Li, Z Qin, Q Wang, T Xu, Y Yang, Z He Computational and structural biotechnology journal 17, 689-698, 2019 | 48 | 2019 |
| Carrier strategies boost the application of CRISPR/Cas system in gene therapy Z Xu, Q Wang, H Zhong, Y Jiang, X Shi, B Yuan, N Yu, S Zhang, X Yuan, ... Exploration 2 (2), 20210081, 2022 | 40 | 2022 |
Leaf HuangProfessor Emeritus, University of North Carolina at Chapel HillVerified email at email.unc.edu
