Dennis Discher
Cited by
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Matrix elasticity directs stem cell lineage specification
AJ Engler, S Sen, HL Sweeney, DE Discher
Cell 126 (4), 677-689, 2006
Tissue cells feel and respond to the stiffness of their substrate
DE Discher, P Janmey, Y Wang
Science 310 (5751), 1139-1143, 2005
Polymer vesicles
DE Discher, A Eisenberg
Science 297 (5583), 967-973, 2002
Polymersomes: tough vesicles made from diblock copolymers
BM Discher, YY Won, DS Ege, JCM Lee, FS Bates, DE Discher, ...
Science 284 (5417), 1143-1146, 1999
Growth factors, matrices, and forces combine and control stem cells
DE Discher, DJ Mooney, PW Zandstra
Science 324 (5935), 1673-1677, 2009
Shape effects of filaments versus spherical particles in flow and drug delivery
YAN Geng, P Dalhaimer, S Cai, R Tsai, M Tewari, T Minko, DE Discher
Nature nanotechnology 2 (4), 249-255, 2007
Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments
AJ Engler, MA Griffin, S Sen, CG Bonnemann, HL Sweeney, DE Discher
The Journal of cell biology 166 (6), 877-887, 2004
Substrate compliance versus ligand density in cell on gel responses
A Engler, L Bacakova, C Newman, A Hategan, M Griffin, D Discher
Biophysical journal 86 (1), 617-628, 2004
Nuclear lamin-A scales with tissue stiffness and enhances matrix-directed differentiation
J Swift, IL Ivanovska, A Buxboim, T Harada, PCDP Dingal, J Pinter, ...
Science 341 (6149), 1240104, 2013
Bio-inspired, bioengineered and biomimetic drug delivery carriers
JW Yoo, DJ Irvine, DE Discher, S Mitragotri
Nature reviews Drug discovery 10 (7), 521-535, 2011
Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating
AJ Engler, C Carag-Krieger, CP Johnson, M Raab, HY Tang, ...
Journal of cell science 121 (22), 3794-3802, 2008
Self-porating polymersomes of PEG–PLA and PEG–PCL: hydrolysis-triggered controlled release vesicles
F Ahmed, DE Discher
Journal of controlled release 96 (1), 37-53, 2004
Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance
MF Berry, AJ Engler, YJ Woo, TJ Pirolli, LT Bish, V Jayasankar, KJ Morine, ...
American Journal of Physiology-Heart and Circulatory Physiology 290 (6 …, 2006
Physical plasticity of the nucleus in stem cell differentiation
JD Pajerowski, KN Dahl, FL Zhong, PJ Sammak, DE Discher
Proceedings of the National Academy of Sciences 104 (40), 15619-15624, 2007
Minimal" Self" peptides that inhibit phagocytic clearance and enhance delivery of nanoparticles
PL Rodriguez, T Harada, DA Christian, DA Pantano, RK Tsai, DE Discher
Science 339 (6122), 971-975, 2013
Molecular weight dependence of polymersome membrane structure, elasticity, and stability
H Bermudez, AK Brannan, DA Hammer, FS Bates, DE Discher
Macromolecules 35 (21), 8203-8208, 2002
Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug
F Ahmed, RI Pakunlu, A Brannan, F Bates, T Minko, DE Discher
Journal of Controlled Release 116 (2), 150-158, 2006
Polymer vesicles in vivo: correlations with PEG molecular weight
PJ Photos, L Bacakova, B Discher, FS Bates, DE Discher
Journal of Controlled Release 90 (3), 323-334, 2003
Temperature‐Controlled Assembly and Release from Polymer Vesicles of Poly (ethylene oxide)‐block‐poly (N‐isopropylacrylamide)
S Qin, Y Geng, DE Discher, S Yang
Advanced Materials 18 (21), 2905-2909, 2006
Preparation, stability, and in vitro performance of vesicles made with diblock copolymers
JCM Lee, H Bermudez, BM Discher, MA Sheehan, YY Won, FS Bates, ...
Biotechnology and bioengineering 73 (2), 135-145, 2001
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