| The VSGB 2.0 model: a next generation energy model for high resolution protein structure modeling J Li, R Abel, K Zhu, Y Cao, S Zhao, RA Friesner Proteins: Structure, Function, and Bioinformatics 79 (10), 2794-2812, 2011 | 898 | 2011 |
| Crystal structure of the human cannabinoid receptor CB1 T Hua, K Vemuri, M Pu, L Qu, GW Han, Y Wu, S Zhao, W Shui, S Li, ... Cell 167 (3), 750-762. e14, 2016 | 563 | 2016 |
| Crystal structures of agonist-bound human cannabinoid receptor CB1 T Hua, K Vemuri, SP Nikas, RB Laprairie, Y Wu, L Qu, M Pu, A Korde, ... Nature 547 (7664), 468-471, 2017 | 470 | 2017 |
| Common activation mechanism of class A GPCRs Q Zhou, D Yang, M Wu, Y Guo, W Guo, L Zhong, X Cai, A Dai, W Jang, ... Elife 8, e50279, 2019 | 398 | 2019 |
| Crystal structure of the human cannabinoid receptor CB2 X Li, T Hua, K Vemuri, JH Ho, Y Wu, L Wu, P Popov, O Benchama, ... Cell 176 (3), 459-467. e13, 2019 | 345 | 2019 |
| G protein-coupled receptors: structure-and function-based drug discovery D Yang, Q Zhou, V Labroska, S Qin, S Darbalaei, Y Wu, E Yuliantie, L Xie, ... Signal transduction and targeted therapy 6 (1), 7, 2021 | 326 | 2021 |
| Activation and signaling mechanism revealed by cannabinoid receptor-Gi complex structures T Hua, X Li, L Wu, C Iliopoulos-Tsoutsouvas, Y Wang, M Wu, L Shen, ... Cell 180 (4), 655-665. e18, 2020 | 249 | 2020 |
| 5-HT2C receptor structures reveal the structural basis of GPCR polypharmacology Y Peng, JD McCorvy, K Harpsøe, K Lansu, S Yuan, P Popov, L Qu, M Pu, ... Cell 172 (4), 719-730. e14, 2018 | 226 | 2018 |
| Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators G Song, D Yang, Y Wang, C De Graaf, Q Zhou, S Jiang, K Liu, X Cai, ... Nature 546 (7657), 312-315, 2017 | 224 | 2017 |
| Discovery of new enzymes and metabolic pathways by using structure and genome context S Zhao, R Kumar, A Sakai, MW Vetting, BMK Wood, S Brown, ... Nature 502 (7473), 698-702, 2013 | 156 | 2013 |
| Structural basis of CXC chemokine receptor 2 activation and signalling K Liu, L Wu, S Yuan, M Wu, Y Xu, Q Sun, S Li, S Zhao, T Hua, ZJ Liu Nature 585 (7823), 135-140, 2020 | 154 | 2020 |
| Long loop prediction using the protein local optimization program K Zhu, DL Pincus, S Zhao, RA Friesner Proteins: Structure, Function, and Bioinformatics 65 (2), 438-452, 2006 | 143 | 2006 |
| Structural basis for apelin control of the human apelin receptor Y Ma, Y Yue, Y Ma, Q Zhang, Q Zhou, Y Song, Y Shen, X Li, X Ma, C Li, ... Structure 25 (6), 858-866. e4, 2017 | 132 | 2017 |
| Homolytic C− H and N− H bond dissociation energies of strained organic compounds Y Feng, L Liu, JT Wang, SW Zhao, QX Guo The Journal of Organic Chemistry 69 (9), 3129-3138, 2004 | 123 | 2004 |
| Structural basis of ligand recognition and self-activation of orphan GPR52 X Lin, M Li, N Wang, Y Wu, Z Luo, S Guo, GW Han, S Li, Y Yue, X Wei, ... Nature 579 (7797), 152-157, 2020 | 115 | 2020 |
| Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand X Zhang, F Zhao, Y Wu, J Yang, GW Han, S Zhao, A Ishchenko, L Ye, ... Nature communications 8 (1), 15383, 2017 | 111 | 2017 |
| Crystal structure of the Frizzled 4 receptor in a ligand-free state S Yang, Y Wu, TH Xu, PW de Waal, Y He, M Pu, Y Chen, ZJ DeBruine, ... Nature 560 (7720), 666-670, 2018 | 105 | 2018 |
| Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes MW Vetting, N Al-Obaidi, S Zhao, B San Francisco, J Kim, DJ Wichelecki, ... Biochemistry 54 (3), 909-931, 2015 | 105 | 2015 |
| Toward better refinement of comparative models: predicting loops in inexact environments BD Sellers, K Zhu, S Zhao, RA Friesner, MP Jacobson Proteins: Structure, Function, and Bioinformatics 72 (3), 959-971, 2008 | 101 | 2008 |
| Determination of the melanocortin-4 receptor structure identifies Ca2+ as a cofactor for ligand binding J Yu, LE Gimenez, CC Hernandez, Y Wu, AH Wein, GW Han, K McClary, ... Science 368 (6489), 428-433, 2020 | 97 | 2020 |
Raymond StevensiHuman Institute, ShanghaiTech/Bridge Institute, USCVerified email at usc.edu
