Proviral insertion in murine lymphomas 2 (PIM2) oncogene phosphorylates pyruvate kinase M2 (PKM2) and promotes glycolysis in cancer cells Z Yu, X Zhao, L Huang, T Zhang, F Yang, L Xie, S Song, P Miao, L Zhao, ... Journal of Biological Chemistry 288 (49), 35406-35416, 2013 | 92 | 2013 |
DAXX represents a new type of protein-folding enabler L Huang, T Agrawal, G Zhu, S Yu, L Tao, JB Lin, R Marmorstein, J Shorter, ... Nature 597 (7874), 132-137, 2021 | 61 | 2021 |
TRIM11 prevents and reverses protein aggregation and rescues a mouse model of Parkinson’s disease G Zhu, DS Harischandra, S Ghaisas, P Zhang, W Prall, L Huang, ... Cell reports 33 (9), 108418, 2020 | 44 | 2020 |
HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells L Huang, Z Yu, T Zhang, X Zhao, G Huang PLoS One 9 (3), e92949, 2014 | 43 | 2014 |
Interaction with pyruvate kinase M2 destabilizes tristetraprolin by proteasome degradation and regulates cell proliferation in breast cancer L Huang, Z Yu, Z Zhang, W Ma, S Song, G Huang Scientific reports 6 (1), 1-11, 2016 | 38 | 2016 |
PKM2 Thr454 phosphorylation increases its nuclear translocation and promotes xenograft tumor growth in A549 human lung cancer cells Z Yu, L Huang, P Qiao, A Jiang, L Wang, T Yang, S Tang, W Zhang, ... Biochemical and biophysical research communications 473 (4), 953-958, 2016 | 32 | 2016 |
A regulatory feedback loop between HIF-1α and PIM2 in HepG2 cells Z Yu, X Zhao, Y Ge, T Zhang, L Huang, X Zhou, L Xie, J Liu, G Huang PloS one 9 (2), e88301, 2014 | 26 | 2014 |
Small ubiquitin-like modifier 1 modification of pyruvate kinase M2 promotes aerobic glycolysis and cell proliferation in A549 human lung cancer cells S An, L Huang, P Miao, L Shi, M Shen, X Zhao, J Liu, G Huang OncoTargets and therapy 11, 2097, 2018 | 24 | 2018 |
Using a yeast two-hybrid system to identify FTCD as a new regulator for HIF-1α in HepG2 cells Z Yu, Y Ge, L Xie, T Zhang, L Huang, X Zhao, J Liu, G Huang Cellular signalling 26 (7), 1560-1566, 2014 | 20 | 2014 |