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Thomas R. Slaney
Thomas R. Slaney
Principal Scientist at Bristol-Myers Squibb
Verified email at bms.com - Homepage
Title
Cited by
Cited by
Year
Push–pull perfusion sampling with segmented flow for high temporal and spatial resolution in vivo chemical monitoring
TR Slaney, J Nie, ND Hershey, PK Thwar, J Linderman, MA Burns, ...
Analytical chemistry 83 (13), 5207-5213, 2011
1082011
Label free screening of enzyme inhibitors at femtomole scale using segmented flow electrospray ionization mass spectrometry
S Sun, TR Slaney, RT Kennedy
Analytical chemistry 84 (13), 5794-5800, 2012
1032012
Mass Spectrometry “Sensor” for in Vivo Acetylcholine Monitoring
P Song, ND Hershey, OS Mabrouk, TR Slaney, RT Kennedy
Analytical chemistry 84 (11), 4659-4664, 2012
922012
Collection of nanoliter microdialysate fractions in plugs for off-line in vivo chemical monitoring with up to 2 s temporal resolution
M Wang, T Slaney, O Mabrouk, RT Kennedy
Journal of neuroscience methods 190 (1), 39-48, 2010
752010
Microfabricated sampling probes for in vivo monitoring of neurotransmitters
WH Lee, TR Slaney, RW Hower, RT Kennedy
Analytical chemistry 85 (8), 3828-3831, 2013
672013
Chemical gradients within brain extracellular space measured using low flow push–pull perfusion sampling in vivo
TR Slaney, OS Mabrouk, KA Porter-Stransky, BJ Aragona, RT Kennedy
ACS chemical neuroscience 4 (2), 321-329, 2013
602013
Unique impacts of methionine oxidation, tryptophan oxidation, and asparagine deamidation on antibody stability and aggregation
ME Alam, TR Slaney, L Wu, TK Das, S Kar, GV Barnett, A Leone, ...
Journal of Pharmaceutical Sciences 109 (1), 656-669, 2020
432020
Enhancing host-cell protein detection in protein therapeutics using HILIC enrichment and proteomic analysis
Q Wang, TR Slaney, W Wu, R Ludwig, L Tao, A Leone
Analytical Chemistry 92 (15), 10327-10335, 2020
312020
Deamidation can compromise antibody colloidal stability and enhance aggregation in a pH-dependent manner
ME Alam, GV Barnett, TR Slaney, CG Starr, TK Das, PM Tessier
Molecular pharmaceutics 16 (5), 1939-1949, 2019
292019
Probing the tryptophan environment in therapeutic proteins: Implications for higher order structure on tryptophan oxidation
GV Barnett, G Balakrishnan, N Chennamsetty, L Hoffman, J Bongers, ...
Journal of Pharmaceutical Sciences 108 (6), 1944-1952, 2019
202019
Identification of a host cell protein impurity in therapeutic protein, P1
D Ahluwalia, H Dhillon, T Slaney, H Song, H Boux, S Mehta, L Zhang, ...
Journal of pharmaceutical and biomedical analysis 141, 32-38, 2017
162017
Ion Mobility-Mass Spectrometry and Collision-Induced Unfolding of Designed Bispecific Antibody Therapeutics
RC Villafuerte-Vega, HW Li, TR Slaney, N Chennamsetty, G Chen, L Tao, ...
Analytical chemistry 95 (17), 6962-6970, 2023
52023
Characterization of protein therapeutics by mass spectrometry
W Wu, H Song, T Slaney, R Ludwig, L Tao, T Das
Protein Analysis Using Mass Spectrometry: Accelerating Protein …, 2017
32017
Enzymatic removal of sialic acid enables iCIEF stability monitoring of charge variants of a highly sialylated bispecific antibody
BH Peters, J Bautista, TR Slaney, H Guo, RYC Huang, ME Krause, ...
Electrophoresis 43 (9-10), 1059-1067, 2022
22022
Codon-Directed Determination of the Biological Causes of Sequence Variants in Therapeutic Proteins
T Jiang, H Song, TR Slaney, W Wu, E Langsdorf, G Gupta, R Ludwig, ...
Analytical chemistry 89 (23), 12749-12755, 2017
22017
Low-flow push-pull perfusion for measuring neurotransmitters with high spatial and temporal resolution within the living brain
TR Slaney
University of Michigan, 2013
22013
A comprehensive strategy for the identification of biologics by liquid-chromatography–mass spectrometry for release testing in a regulated environment
A Morales, J Candreva, T Jayarathne, AL Esterman, S Voruganti, ...
Journal of Pharmaceutical and Biomedical Analysis 234, 115580, 2023
2023
Screening Clones for Monoclonal Antibody Production Using Droplet Microfluidics Interfaced to Electrospray Ionization Mass Spectrometry
CI D’Amico, G Robbins, I Po, Z Fang, TR Slaney, G Tremml, L Tao, ...
Journal of the American Society for Mass Spectrometry 34 (6), 1117-1124, 2023
2023
Ceramic hydroxyapatite chromatography plays a critical role in bispecific antibody purification process for impurity removal
JA Waller, J Zheng, R Dyer, T Slaney, W Wu, L Tao, S Ghose
Antibody Therapeutics 6 (1), 30-37, 2023
2023
Deamidation compromises antibody colloidal stability and solubility in a pH-dependent manner
M Alam, G Barnett, T Slaney, T Das, P Tessier
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019
2019
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