Karen C. Crasta
Karen C. Crasta
National University of Singapore, Yong Loo Lin School of Medicine, Dept of Physiology and NUHS
Verified email at - Homepage
Cited by
Cited by
DNA breaks and chromosome pulverization from errors in mitosis
K Crasta, NJ Ganem, R Dagher, AB Lantermann, EV Ivanova, Y Pan, ...
Nature 482 (7383), 53-58, 2012
Identification and Characterization of CAMP Cohemolysin as a Potential Virulence Factor of Riemerella anatipestifer
KC Crasta, KL Chua, S Subramaniam, J Frey, H Loh, HM Tan
Journal of bacteriology 184 (7), 1932-1939, 2002
Cdk1 regulates centrosome separation by restraining proteolysis of microtubule‐associated proteins
K Crasta, P Huang, G Morgan, M Winey, U Surana
The EMBO journal 25 (11), 2551-2563, 2006
Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle
K Crasta, HH Lim, TH Giddings, M Winey, U Surana
Nature cell biology 10 (6), 665-675, 2008
DNA replication checkpoint prevents precocious chromosome segregation by regulating spindle behavior
V Krishnan, S Nirantar, K Crasta, AYH Cheng, U Surana
Molecular cell 16 (5), 687-700, 2004
Mutational game changer: Chromothripsis and its emerging relevance to cancer
MNH Luijten, JXT Lee, KC Crasta
Mutation Research/Reviews in Mutation Research 777, 29-51, 2018
Dropping in on lipid droplets: insights into cellular stress and cancer
P Shyu, XFA Wong, K Crasta, G Thibault
Bioscience reports 38 (5), 2018
Consequences of mitotic slippage for antimicrotubule drug therapy
B Cheng, K Crasta
Endocrine-related cancer 24 (9), T97-T106, 2017
Exosomes as emerging pro-tumorigenic mediators of the senescence-associated secretory phenotype
R Jakhar, K Crasta
International journal of molecular sciences 20 (10), 2547, 2019
Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects
Q He, B Au, M Kulkarni, Y Shen, K Lim, J Maimaiti, C Wong, M Luijten, ...
Oncogenesis 7 (8), 1-18, 2018
Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes
K Crasta, U Surana
Cell division 1 (1), 1-8, 2006
Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation
JWK Ku, Y Chen, BJW Lim, S Gasser, KC Crasta, YH Gan
Proceedings of the National Academy of Sciences 117 (27), 15923-15934, 2020
Autophagy governs protumorigenic effects of mitotic slippage–induced senescence
R Jakhar, MNH Luijten, AXF Wong, B Cheng, K Guo, SP Neo, B Au, ...
Molecular Cancer Research 16 (11), 1625-1640, 2018
Generation of micronuclei and detection of chromosome pulverization
MNH Luijten, JXT Lee, S Chen, KC Crasta
Chromothripsis, 183-195, 2018
Consorting kinases, end of destruction and birth of a spindle
K Crasta, H Hwa Lim, T Zhang, S Nirantar, U Surana
Cell Cycle 7 (19), 2960-2966, 2008
Increased double strand breaks in diabetic β-cells with a p21 response that limits apoptosis
VSY Tay, S Devaraj, T Koh, G Ke, KC Crasta, Y Ali
Scientific Reports 9 (1), 1-10, 2019
Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment
A Wong, S Chen, LK Yang, Y Kanagasundaram, K Crasta
Cell death discovery 4 (1), 1-15, 2018
E2F and STAT3 provide transcriptional synergy for histone variant H2AZ activation to sustain glioblastoma chromatin accessibility and tumorigenicity
J Yoon, OV Grinchuk, R Tirado-Magallanes, ZK Ngian, EXY Tay, ...
Cell Death & Differentiation, 1-16, 2022
Breaking the vicious circle: Extrachromosomal circular DNA as an emerging player in tumour evolution
M Robert, K Crasta
Seminars in cell & developmental biology, 2021
Correction: PLK1 inhibition selectively induces apoptosis in ARID1A deficient cells through uncoupling of oxygen consumption from ATP production
US Srinivas, NSC Tay, P Jaynes, A Anbuselvan, GK Ramachandran, ...
Oncogene, 2022
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