Karen C. Crasta
Karen C. Crasta
National University of Singapore, YLL School of Medicine
Verified email at nus.edu.sg
Cited by
Cited by
DNA breaks and chromosome pulverization from errors in mitosis
K Crasta, NJ Ganem, R Dagher, AB Lantermann, EV Ivanova, Y Pan, ...
Nature 482 (7383), 53-58, 2012
Identification and Characterization of CAMP Cohemolysin as a Potential Virulence Factor of Riemerella anatipestifer
KC Crasta, KL Chua, S Subramaniam, J Frey, H Loh, HM Tan
Journal of bacteriology 184 (7), 1932-1939, 2002
Cdk1 regulates centrosome separation by restraining proteolysis of microtubule‐associated proteins
K Crasta, P Huang, G Morgan, M Winey, U Surana
The EMBO journal 25 (11), 2551-2563, 2006
Inactivation of Cdh1 by synergistic action of Cdk1 and polo kinase is necessary for proper assembly of the mitotic spindle
K Crasta, HH Lim, TH Giddings, M Winey, U Surana
Nature cell biology 10 (6), 665-675, 2008
DNA replication checkpoint prevents precocious chromosome segregation by regulating spindle behavior
V Krishnan, S Nirantar, K Crasta, AYH Cheng, U Surana
Molecular cell 16 (5), 687-700, 2004
Mutational game changer: Chromothripsis and its emerging relevance to cancer
MNH Luijten, JXT Lee, KC Crasta
Mutation Research/Reviews in Mutation Research 777, 29-51, 2018
Consequences of mitotic slippage for antimicrotubule drug therapy
B Cheng, K Crasta
Endocrine-related cancer 24 (9), T97-T106, 2017
Dropping in on lipid droplets: insights into cellular stress and cancer
P Shyu Jr, XFA Wong, K Crasta, G Thibault
Bioscience reports 38 (5), BSR20180764, 2018
Exosomes as emerging pro-tumorigenic mediators of the senescence-associated secretory phenotype
R Jakhar, K Crasta
International journal of molecular sciences 20 (10), 2547, 2019
Chromosomal instability-induced senescence potentiates cell non-autonomous tumourigenic effects
Q He, B Au, M Kulkarni, Y Shen, KJ Lim, J Maimaiti, CK Wong, ...
Oncogenesis 7 (8), 1-18, 2018
Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes
K Crasta, U Surana
Cell division 1 (1), 1-8, 2006
Autophagy governs protumorigenic effects of mitotic slippage–induced senescence
R Jakhar, MNH Luijten, AXF Wong, B Cheng, K Guo, SP Neo, B Au, ...
Molecular Cancer Research 16 (11), 1625-1640, 2018
Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation
JWK Ku, Y Chen, BJW Lim, S Gasser, KC Crasta, YH Gan
Proceedings of the National Academy of Sciences 117 (27), 15923-15934, 2020
Consorting kinases, end of destruction and birth of a spindle
K Crasta, H Hwa Lim, T Zhang, S Nirantar, U Surana
Cell Cycle 7 (19), 2960-2966, 2008
Generation of micronuclei and detection of chromosome pulverization
MNH Luijten, JXT Lee, S Chen, KC Crasta
Chromothripsis, 183-195, 2018
Increased double strand breaks in diabetic β-cells with a p21 response that limits apoptosis
VSY Tay, S Devaraj, T Koh, G Ke, KC Crasta, Y Ali
Scientific reports 9 (1), 1-10, 2019
Lipid accumulation facilitates mitotic slippage-induced adaptation to anti-mitotic drug treatment
A Wong, S Chen, LK Yang, Y Kanagasundaram, K Crasta
Cell death discovery 4 (1), 1-15, 2018
Lipid metabolism is involved in mitotic slippage-induced SASP upon treatment with anti-mitotic drugs
KC Crasta, A Wong, B Lim
Cancer Research 79 (13 Supplement), 897-897, 2019
Quantitative phase imaging of mitotic cells using d’Biomager
A Asundi, K Crasta, R Elsa
Workshop on Computational Methods in Bio-imaging Sciences 8, 12, 2018
50 years on… the discovery of tubulin continues to advance cancer treatment
K Crasta, R Aneja
Endocrine-related cancer 24 (9), E3-E5, 2017
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