Srinivasan Ramachandran
Srinivasan Ramachandran
Research Scientist
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Truncated β-amyloid peptide channels provide an alternative mechanism for Alzheimer’s disease and Down syndrome
H Jang, FT Arce, S Ramachandran, R Capone, R Azimova, BL Kagan, ...
Proceedings of the National Academy of Sciences 107 (14), 6538-6543, 2010
Magnetic targeting of nanoparticles across the intact blood–brain barrier
SD Kong, J Lee, S Ramachandran, BP Eliceiri, VI Shubayev, R Lal, S Jin
Journal of controlled release 164 (1), 49-57, 2012
Antimicrobial properties of amyloid peptides
BL Kagan, H Jang, R Capone, F Teran Arce, S Ramachandran, R Lal, ...
Molecular pharmaceutics 9 (4), 708-717, 2012
A novel role for connexin hemichannel in oxidative stress and smoking-induced cell injury
S Ramachandran, LH Xie, SA John, S Subramaniam, R Lal
PLoS one 2 (8), e712, 2007
Cisplatin nanoliposomes for cancer therapy: AFM and fluorescence imaging of cisplatin encapsulation, stability, cellular uptake, and toxicity
S Ramachandran, AP Quist, S Kumar, R Lal
Langmuir 22 (19), 8156-8162, 2006
β-Barrel topology of Alzheimer's β-amyloid ion channels
H Jang, FT Arce, S Ramachandran, R Capone, R Lal, R Nussinov
Journal of molecular biology 404 (5), 917-934, 2010
Atomic Force Microscopy and MD Simulations Reveal Pore-Like Structures of All-d-Enantiomer of Alzheimer’s β-Amyloid Peptide: Relevance to the Ion Channel …
L Connelly, H Jang, F Teran Arce, R Capone, SA Kotler, ...
The journal of physical chemistry B 116 (5), 1728-1735, 2012
Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane
H Jang, L Connelly, F Teran Arce, S Ramachandran, BL Kagan, R Lal, ...
Journal of chemical theory and computation 9 (1), 822-833, 2013
Therapeutic hypothermia cardioprotection via Akt-and nitric oxide-mediated attenuation of mitochondrial oxidants
ZH Shao, WW Sharp, KR Wojcik, CQ Li, M Han, WT Chang, ...
American Journal of Physiology-Heart and Circulatory Physiology 298 (6 …, 2010
Misfolded amyloid ion channels present mobile β-sheet subunits in contrast to conventional ion channels
H Jang, FT Arce, R Capone, S Ramachandran, R Lal, R Nussinov
Biophysical journal 97 (11), 3029-3037, 2009
Antimicrobial protegrin-1 forms amyloid-like fibrils with rapid kinetics suggesting a functional link
H Jang, FT Arce, M Mustata, S Ramachandran, R Capone, R Nussinov, ...
Biophysical journal 100 (7), 1775-1783, 2011
Nanomechanics of hemichannel conformations: connexin flexibility underlying channel opening and closing
F Liu, FT Arce, S Ramachandran, R Lal
Journal of Biological Chemistry 281 (32), 23207-23217, 2006
Structural convergence among diverse, toxic β-sheet ion channels
H Jang, F Teran Arce, S Ramachandran, R Capone, R Lal, R Nussinov
The journal of physical chemistry B 114 (29), 9445-9451, 2010
Disordered amyloidogenic peptides may insert into the membrane and assemble into common cyclic structural motifs
H Jang, FT Arce, S Ramachandran, BL Kagan, R Lal, R Nussinov
Chemical Society reviews 43 (19), 6750-6764, 2014
Baicalein protects against doxorubicin‐induced cardiotoxicity by attenuation of mitochondrial oxidant injury and JNK activation
WT Chang, J Li, HH Haung, H Liu, M Han, S Ramachandran, CQ Li, ...
Journal of cellular biochemistry 112 (10), 2873-2881, 2011
Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation
FT Arce, H Jang, S Ramachandran, PB Landon, R Nussinov, R Lal
Soft Matter 7 (11), 5267-5273, 2011
The effects of ginsenoside Rb1 on JNK in oxidative injury in cardiomyocytes
J Li, ZH Shao, JT Xie, CZ Wang, S Ramachandran, JJ Yin, H Aung, CQ Li, ...
Archives of pharmacal research 35 (7), 1259-1267, 2012
Grape seed proanthocyanidins ameliorate Doxorubicin-induced cardiotoxicity
J Li, H Liu, S Ramachandran, GB Waypa, JJ Yin, CQ Li, M Han, ...
The American journal of Chinese medicine 38 (03), 569-584, 2010
K3 Fragment of Amyloidogenic β2-Microglobulin Forms Ion Channels: Implication for Dialysis Related Amyloidosis
M Mustata, R Capone, H Jang, FT Arce, S Ramachandran, R Lal, ...
Journal of the American Chemical Society 131 (41), 14938-14945, 2009
Atomic force microscopy imaging and electrical recording of lipid bilayers supported over microfabricated silicon chip nanopores: Lab-on-a-chip system for lipid membranes and …
AP Quist, A Chand, S Ramachandran, C Daraio, S Jin, R Lal
Langmuir 23 (3), 1375-1380, 2007
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