Mutant Profilin1 transgenic mice recapitulate cardinal features of motor neuron disease D Fil, A DeLoach, S Yadav, D Alkam, M MacNicol, A Singh, ... Human molecular genetics 26 (4), ddw429, 2017 | 85 | 2017 |
Macrophage enzyme and reduced inflammation drive brain correction of mucopolysaccharidosis IIIB by stem cell gene therapy RJ Holley, SM Ellison, D Fil, C O’Leary, J McDermott, N Senthivel, ... Brain 141 (1), 99-116, 2018 | 73 | 2018 |
Peripheral challenge with double‐stranded RNA elicits global up‐regulation of cytokine gene expression in the brain GW Konat, E Borysiewicz, D Fil, I James Journal of neuroscience research 87 (6), 1381-1388, 2009 | 58 | 2009 |
Rho proteins are negative regulators of TLR2, TLR3, and TLR4 signaling in astrocytes E Borysiewicz, D Fil, GW Konat Journal of neuroscience research 87 (7), 1565-1572, 2009 | 36 | 2009 |
Excision of the expanded GAA repeats corrects cardiomyopathy phenotypes of iPSC-derived Friedreich's ataxia cardiomyocytes J Li, N Rozwadowska, A Clark, D Fil, JS Napierala, M Napierala Stem cell research 40, 101529, 2019 | 33 | 2019 |
A broad upregulation of cerebral chemokine genes by peripherally-generated inflammatory mediators D Fil, E Borysiewicz, GW Konat Metabolic brain disease 26, 49-59, 2011 | 32 | 2011 |
NADPH oxidase pathway is involved in aortic contraction induced by A3 adenosine receptor in mice MS El-Awady, HR Ansari, D Fil, SL Tilley, SJ Mustafa Journal of Pharmacology and Experimental Therapeutics 338 (2), 711-717, 2011 | 31 | 2011 |
Functional and RNA expression profile of adenosine receptor subtypes in mouse mesenteric arteries B Teng, D Fil, SL Tilley, C Ledent, T Krahn, SJ Mustafa Journal of cardiovascular pharmacology 61 (1), 70-76, 2013 | 27 | 2013 |
RNA-Seq Analysis of Spinal Cord Tissues from hPFN1G118V Transgenic Mouse Model of ALS at Pre-symptomatic and End-Stages of Disease C Barham, D Fil, SD Byrum, Y Rahmatallah, G Glazko, M Kiaei Scientific reports 8 (1), 13737, 2018 | 17 | 2018 |
Peripheral immune challenge with dsRNA enhances kainic acid-induced status epilepticus LT Kirschman, E Borysiewicz, D Fil, GW Konat Metabolic brain disease 26, 91-93, 2011 | 16 | 2011 |
Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreich's ataxia D Fil, BK Chacko, R Conley, X Ouyang, J Zhang, VM Darley-Usmar, ... Disease models & mechanisms 13 (7), dmm045229, 2020 | 11 | 2020 |
Phosphodiesterase 4B2 gene is an effector of Toll-like receptor signaling in astrocytes E Borysiewicz, D Fil, D Dlaboga, JM O’Donnell, GW Konat Metabolic brain disease 24, 481-491, 2009 | 11 | 2009 |
Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models A Urbaniak, MR Reed, D Fil, A Moorjani, S Heflin, M Antoszczak, M Sulik, ... Biomedicine & Pharmacotherapy 141, 111815, 2021 | 8 | 2021 |
Analysis of extinction acquisition to attenuated tones in prenatally stressed and non-stressed offspring following auditory fear conditioning AK Salm, BE Lally, E Borysiewicz, D Fil, G Konat Physiology & Behavior 139, 157-166, 2015 | 5 | 2015 |
Neurobehavioral deficits of mice expressing a low level of G127V mutant frataxin D Fil, RL Conley, AR Zuberi, CM Lutz, T Gemelli, M Napierala, ... Neurobiology of disease 177, 105996, 2023 | 2 | 2023 |
PLP1-lacZ transgenic mice reveal that splice variants containing “human-specific” exons are relatively minor in comparison to the archetypal transcript and that an upstream … P Patyal, D Fil, H Hamdan, PA Wight Frontiers in Cellular Neuroscience 16, 1087145, 2023 | 2 | 2023 |
Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4+ helper and CD8+ effector T cells AC Azevedo‐Pouly, LE Appell, L Burdine, LJ Rogers, LC Morehead, D Fil, ... Immunology and Cell Biology 101 (7), 663-671, 2023 | 1 | 2023 |
Neurological correction of mucopolysaccharidosis type IIIB mice by haematopoietic stem cell gene therapy B Bigger, S Ellison, D Fil, C O'leary, J McDermott, N Senthivel, ... Molecular Genetics and Metabolism 1 (120), S28, 2017 | 1 | 2017 |
Synergistic action of ATF6 and EZH2 in sensing metabolic stress to boost anti-tumor immunity JL Edmondson, MR Reed, D Fil, B Heflin, B Koss, AJ Tackett Cancer Research 84 (6_Supplement), 584-584, 2024 | | 2024 |
255 Functional and multi-omic characterization of CAR T cells across healthy donors D Fil, LJ Rogers, B Koss, MA Bauer Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |