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Toni-Kim Clarke
Toni-Kim Clarke
Forest Research
Verified email at forestresearch.gov.uk
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Year
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
25232018
Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
DM Howard, MJ Adams, TK Clarke, JD Hafferty, J Gibson, M Shirali, ...
Nature neuroscience 22 (3), 343-352, 2019
17762019
Genome-wide association study identifies 30 loci associated with bipolar disorder
EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ...
Nature genetics 51 (5), 793-803, 2019
13512019
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ...
Cell 179 (7), 1469-1482. e11, 2019
10032019
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
N Mullins, AJ Forstner, KS O’Connell, B Coombes, JRI Coleman, Z Qiao, ...
Nature genetics 53 (6), 817-829, 2021
6872021
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
RK Walters, R Polimanti, EC Johnson, JN McClintick, MJ Adams, ...
Nature neuroscience 21 (12), 1656-1669, 2018
5572018
Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
DM Howard, MJ Adams, M Shirali, TK Clarke, RE Marioni, G Davies, ...
Nature communications 9 (1), 1470, 2018
5172018
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ...
Cell 173 (7), 1705-1715. e16, 2018
4982018
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N= 112 117)
TK Clarke, MJ Adams, G Davies, DM Howard, LS Hall, S Padmanabhan, ...
Molecular psychiatry 22 (10), 1376-1384, 2017
3932017
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism
M Luciano, SP Hagenaars, G Davies, WD Hill, TK Clarke, M Shirali, ...
Nature genetics 50 (1), 6-11, 2018
3372018
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption
G Schumann, LJ Coin, A Lourdusamy, P Charoen, KH Berger, D Stacey, ...
Proceedings of the National Academy of Sciences 108 (17), 7119-7124, 2011
3192011
Genome-wide association study meta-analysis of the alcohol use disorders identification test (AUDIT) in two population-based cohorts
S Sanchez-Roige, AA Palmer, P Fontanillas, SL Elson, ...
American Journal of Psychiatry 176 (2), 107-118, 2019
3052019
Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits
H Zhou, JM Sealock, S Sanchez-Roige, TK Clarke, DF Levey, Z Cheng, ...
Nature neuroscience 23 (7), 809-818, 2020
2652020
Minimal phenotyping yields genome-wide association signals of low specificity for major depression
N Cai, JA Revez, MJ Adams, TFM Andlauer, G Breen, EM Byrne, ...
Nature genetics 52 (4), 437-447, 2020
255*2020
KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
G Schumann, C Liu, P O’Reilly, H Gao, P Song, B Xu, B Ruggeri, N Amin, ...
Proceedings of the National Academy of Sciences 113 (50), 14372-14377, 2016
2462016
A large-scale genome-wide association study meta-analysis of cannabis use disorder
EC Johnson, D Demontis, TE Thorgeirsson, RK Walters, R Polimanti, ...
The Lancet Psychiatry 7 (12), 1032-1045, 2020
2212020
Common polygenic risk for autism spectrum disorder (ASD) is associated with cognitive ability in the general population
TK Clarke, MK Lupton, AM Fernandez-Pujals, J Starr, G Davies, S Cox, ...
Molecular psychiatry 21 (3), 419-425, 2016
2192016
Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation
JL Min, G Hemani, E Hannon, KF Dekkers, J Castillo-Fernandez, R Luijk, ...
Nature genetics 53 (9), 1311-1321, 2021
2092021
Major depressive disorder working group of the psychiatric genomics consortium
DM Howard, MJ Adams, WD Hill, TK Clarke, MJ Adams, TK Clarke, ...
Nat. Commun 11, 230, 2020
1942020
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia
SH Witt, F Streit, M Jungkunz, J Frank, S Awasthi, CS Reinbold, ...
Translational psychiatry 7 (6), e1155-e1155, 2017
1842017
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