Steven Arnold
Steven Arnold
Professor of neurology, Harvard Medical School
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Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ...
Nature genetics 51 (3), 414-430, 2019
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
AC Naj, G Jun, GW Beecham, LS Wang, BN Vardarajan, J Buros, ...
Nature genetics 43 (5), 436-441, 2011
Demonstrated brain insulin resistance in Alzheimer’s disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline
K Talbot, HY Wang, H Kazi, LY Han, KP Bakshi, A Stucky, RL Fuino, ...
The Journal of clinical investigation 122 (4), 1316-1338, 2012
Loneliness and risk of Alzheimer disease
RS Wilson, KR Krueger, SE Arnold, JA Schneider, JF Kelly, LL Barnes, ...
Archives of general psychiatry 64 (2), 234-240, 2007
The topographical and neuroanatomical distribution of neurofibrillary tangles and neuritic plaques in the cerebral cortex of patients with Alzheimer's disease
SE Arnold, BT Hyman, J Flory, AR Damasio, GW Van Hoesen
Cerebral cortex 1 (1), 103-116, 1991
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis
WJ Jansen, R Ossenkoppele, DL Knol, BM Tijms, P Scheltens, ...
Jama 313 (19), 1924-1938, 2015
Primary age-related tauopathy (PART): a common pathology associated with human aging
JF Crary, JQ Trojanowski, JA Schneider, JF Abisambra, EL Abner, ...
Acta neuropathologica 128, 755-766, 2014
Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums
SE Arnold, Z Arvanitakis, SL Macauley-Rambach, AM Koenig, HY Wang, ...
Nature Reviews Neurology 14 (3), 168-181, 2018
Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
Y Iturria-Medina, RC Sotero, PJ Toussaint, JM Mateos-Pérez, AC Evans
Nature communications 7 (1), 11934, 2016
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
R Sims, SJ Van Der Lee, AC Naj, C Bellenguez, N Badarinarayan, ...
Nature genetics 49 (9), 1373-1384, 2017
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s disease–associated Aβ oligomers
TR Bomfim, L Forny-Germano, LB Sathler, J Brito-Moreira, JC Houzel, ...
The Journal of clinical investigation 122 (4), 1339-1353, 2012
The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study
DA Bennett, JA Schneider, Y Tang, SE Arnold, RS Wilson
The Lancet Neurology 5 (5), 406-412, 2006
Contribution of cerebrovascular disease in autopsy confirmed neurodegenerative disease cases in the National Alzheimer’s Coordinating Centre
JB Toledo, SE Arnold, K Raible, J Brettschneider, SX Xie, M Grossman, ...
Brain 136 (9), 2697-2706, 2013
Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson’s disease
HI Hurtig, JQ Trojanowski, J Galvin, D Ewbank, ML Schmidt, VMY Lee, ...
Neurology 54 (10), 1916-1921, 2000
Education modifies the relation of AD pathology to level of cognitive function in older persons
DA Bennett, RS Wilson, JA Schneider, DA Evans, CF Mendes de Leon, ...
Neurology 60 (12), 1909-1915, 2003
FDG-PET improves accuracy in distinguishing frontotemporal dementia and Alzheimer's disease
NL Foster, JL Heidebrink, CM Clark, WJ Jagust, SE Arnold, NR Barbas, ...
Brain 130 (10), 2616-2635, 2007
Altered neuregulin 1–erbB4 signaling contributes to NMDA> receptor hypofunction in schizophrenia
CG Hahn, HY Wang, DS Cho, K Talbot, RE Gur, WH Berrettini, K Bakshi, ...
Nature medicine 12 (7), 824-828, 2006
Depressive symptoms, cognitive decline, and risk of AD in older persons
RS Wilson, LL Barnes, CF Mendes de Leon, NT Aggarwal, JS Schneider, ...
Neurology 59 (3), 364-370, 2002
Identification of common variants influencing risk of the tauopathy progressive supranuclear palsy
GU Höglinger, NM Melhem, DW Dickson, PMA Sleiman, LS Wang, L Klei, ...
Nature genetics 43 (7), 699-705, 2011
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions
VM Van Deerlin, PMA Sleiman, M Martinez-Lage, A Chen-Plotkin, ...
Nature genetics 42 (3), 234-239, 2010
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