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John E. Pearl
John E. Pearl
Verified email at leicester.ac.uk
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IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge
SA Khader, GK Bell, JE Pearl, JJ Fountain, J Rangel-Moreno, GE Cilley, ...
Nature immunology 8 (4), 369-377, 2007
17292007
Randomized clinical trial of pressure-controlled inverse ratio ventilation and extracorporeal CO2 removal for adult respiratory distress syndrome.
AH Morris, CJ Wallace, RL Menlove, TP Clemmer, JF Orme Jr, LK Weaver, ...
American journal of respiratory and critical care medicine 149 (2), 295-305, 1994
12421994
IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-γ responses …
SA Khader, JE Pearl, K Sakamoto, L Gilmartin, GK Bell, DM Jelley-Gibbs, ...
The Journal of Immunology 175 (2), 788-795, 2005
6172005
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study
RA Evans, H McAuley, EM Harrison, A Shikotra, A Singapuri, M Sereno, ...
The Lancet Respiratory Medicine 9 (11), 1275-1287, 2021
4702021
Interleukin 12p40 is required for dendritic cell migration and T cell priming after Mycobacterium tuberculosis infection
SA Khader, S Partida-Sanchez, G Bell, DM Jelley-Gibbs, S Swain, ...
The Journal of experimental medicine 203 (7), 1805-1815, 2006
4212006
Cutting edge: IFN-γ regulates the induction and expansion of IL-17-producing CD4 T cells during mycobacterial infection
A Cruz, SA Khader, E Torrado, A Fraga, JE Pearl, J Pedrosa, AM Cooper, ...
The Journal of Immunology 177 (3), 1416-1420, 2006
4052006
Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study
RA Evans, OC Leavy, M Richardson, O Elneima, HJC McAuley, ...
The Lancet Respiratory Medicine 10 (8), 761-775, 2022
2842022
ESAT-6-specific CD4 T cell responses to aerosol Mycobacterium tuberculosis infection are initiated in the mediastinal lymph nodes
WW Reiley, MD Calayag, ST Wittmer, JL Huntington, JE Pearl, ...
Proceedings of the National Academy of Sciences 105 (31), 10961-10966, 2008
2752008
IL-23 is required for long-term control of Mycobacterium tuberculosis and B cell follicle formation in the infected lung
SA Khader, L Guglani, J Rangel-Moreno, R Gopal, BA Fallert Junecko, ...
The Journal of Immunology 187 (10), 5402-5407, 2011
2162011
Expression of the Nitric Oxide Synthase 2 Gene Is Not Essential for Early Control of Mycobacterium tuberculosis in the Murine Lung
AM Cooper, JE Pearl, JV Brooks, S Ehlers, IM Orme
Infection and immunity 68 (12), 6879-6882, 2000
1732000
IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice
JE Pearl, SA Khader, A Solache, L Gilmartin, N Ghilardi, F Desauvage, ...
The Journal of Immunology 173 (12), 7490-7496, 2004
1702004
Inflammation and lymphocyte activation during mycobacterial infection in the interferon-γ-deficient mouse
JE Pearl, B Saunders, S Ehlers, IM Orme, AM Cooper
Cellular immunology 211 (1), 43-50, 2001
1672001
CD8-and CD95/95L-dependent mechanisms of resistance in mice with chronic pulmonary tuberculosis
J Turner, CD D'souza, JE Pearl, P Marietta, M Noel, AA Frank, ...
American journal of respiratory cell and molecular biology 24 (2), 203-209, 2001
1432001
In a murine tuberculosis model, the absence of homeostatic chemokines delays granuloma formation and protective immunity
SA Khader, J Rangel-Moreno, JJ Fountain, CA Martino, WW Reiley, ...
The Journal of Immunology 183 (12), 8004-8014, 2009
1382009
Cutting edge: T-bet and IL-27R are critical for in vivo IFN-γ production by CD8 T cells during infection
KD Mayer, K Mohrs, W Reiley, S Wittmer, JE Kohlmeier, JE Pearl, ...
The Journal of Immunology 180 (2), 693-697, 2008
1122008
Interleukin 27R regulates CD4+ T cell phenotype and impacts protective immunity during Mycobacterium tuberculosis infection
E Torrado, JJ Fountain, M Liao, M Tighe, WW Reiley, RP Lai, G Meintjes, ...
Journal of Experimental Medicine 212 (9), 1449-1463, 2015
772015
Differential and site specific impact of B cells in the protective immune response to Mycobacterium tuberculosis in the mouse
E Torrado, JJ Fountain, RT Robinson, CA Martino, JE Pearl, ...
PloS one 8 (4), e61681, 2013
672013
Mycobacterium tuberculosis infection induces il12rb1 splicing to generate a novel IL-12Rβ1 isoform that enhances DC migration
RT Robinson, SA Khader, CA Martino, JJ Fountain, M Teixeira-Coelho, ...
Journal of Experimental Medicine 207 (3), 591-605, 2010
612010
Residual lung abnormalities after COVID-19 hospitalization: interim analysis of the UKILD post–COVID-19 study
I Stewart, J Jacob, PM George, PL Molyneaux, JC Porter, RJ Allen, ...
American journal of respiratory and critical care medicine 207 (6), 693-703, 2023
602023
Gamma Interferon-Induced T-Cell Loss in Virulent Mycobacterium avium Infection
M Flórido, JE Pearl, A Solache, M Borges, L Haynes, AM Cooper, ...
Infection and immunity 73 (6), 3577-3586, 2005
602005
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Articles 1–20