| Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments GR Masson, JE Burke, NG Ahn, GS Anand, C Borchers, S Brier, ... Nature Methods 16 (7), 595, 2019 | 524 | 2019 |
| Semi-automated data processing of hydrogen exchange mass spectra using HX-Express DD Weis, JR Engen, IJ Kass Journal of the American Society for Mass Spectrometry 17, 1700-1703, 2006 | 286 | 2006 |
| Identification and characterization of EX1 kinetics in H/D exchange mass spectrometry by peak width analysis DD Weis, TE Wales, JR Engen, M Hotchko, LF Ten Eyck Journal of the American Society for Mass Spectrometry 17, 1498-1509, 2006 | 251 | 2006 |
| Water content and morphology of sodium chloride aerosol particles DD Weis, GE Ewing Journal of Geophysical Research: Atmospheres 104 (D17), 21275-21285, 1999 | 170 | 1999 |
| Analysis of overlapped and noisy hydrogen/deuterium exchange mass spectra M Guttman, DD Weis, JR Engen, KK Lee Journal of The American Society for Mass Spectrometry 24 (12), 1906-1912, 2013 | 169 | 2013 |
| Structural basis for activation of calcineurin by calmodulin J Rumi-Masante, FI Rusinga, TE Lester, TB Dunlap, TD Williams, ... Journal of molecular biology 415 (2), 307-317, 2012 | 133 | 2012 |
| Effects of salts from the Hofmeister series on the conformational stability, aggregation propensity, and local flexibility of an IgG1 monoclonal antibody R Majumdar, P Manikwar, JM Hickey, HS Samra, HA Sathish, SM Bishop, ... Biochemistry 52 (19), 3376-3389, 2013 | 120 | 2013 |
| Infrared spectroscopic signatures of (NH4) 2SO4 aerosols DD Weis, GE Ewing Journal of Geophysical Research: Atmospheres 101 (D13), 18709-18720, 1996 | 113 | 1996 |
| Correlating excipient effects on conformational and storage stability of an IgG1 monoclonal antibody with local dynamics as measured by hydrogen/deuterium‐exchange mass … P Manikwar, R Majumdar, JM Hickey, SV Thakkar, HS Samra, HA Sathish, ... Journal of pharmaceutical sciences 102 (7), 2136-2151, 2013 | 102 | 2013 |
| Mapping unstructured regions and synergistic folding in intrinsically disordered proteins with amide H/D exchange mass spectrometry TR Keppel, BA Howard, DD Weis Biochemistry 50 (40), 8722-8732, 2011 | 91 | 2011 |
| Charge-mediated Fab-Fc interactions in an IgG1 antibody induce reversible self-association, cluster formation, and elevated viscosity J Arora, Y Hu, R Esfandiary, HA Sathish, SM Bishop, SB Joshi, ... mAbs 8 (8), 1561-1574, 2016 | 87 | 2016 |
| Mapping Residual Structure in Intrinsically Disordered Proteins at Residue Resolution Using Millisecond Hydrogen/Deuterium Exchange and Residue Averaging TR Keppel, DD Weis Journal of The American Society for Mass Spectrometry 26 (4), 547-554, 2015 | 84 | 2015 |
| The reaction of nitrogen dioxide with sea salt aerosol DD Weis, GE Ewing The Journal of Physical Chemistry A 103 (25), 4865-4873, 1999 | 84 | 1999 |
| Reliable identification of significant differences in differential hydrogen exchange-mass spectrometry measurements using a hybrid significance testing approach TS Hageman, DD Weis Analytical chemistry 91 (13), 8008-8016, 2019 | 81 | 2019 |
| Hydrogen-deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies R Majumdar, CR Middaugh, DD Weis, DB Volkin Journal of pharmaceutical sciences 104 (2), 327-345, 2015 | 80 | 2015 |
| Hydrogen–deuterium exchange mass spectrometry as an emerging analytical tool for stabilization and formulation development of therapeutic monoclonal antibodies R Majumdar, CR Middaugh, DD Weis, DB Volkin Journal of pharmaceutical sciences 104 (2), 327-345, 2015 | 80 | 2015 |
| Hydrogen Exchange Mass Spectrometry of Proteins DD Weis John Wiley & Sons, 2015 | 79* | 2015 |
| Minimizing carry-over in an online pepsin digestion system used for the H/D exchange mass spectrometric analysis of an IgG1 monoclonal antibody R Majumdar, P Manikwar, JM Hickey, J Arora, CR Middaugh, DB Volkin, ... Journal of the American Society for Mass Spectrometry 23 (12), 2140-2148, 2012 | 77 | 2012 |
| Hydrogen exchange mass spectrometry reveals protein interfaces and distant dynamic coupling effects during the reversible self-association of an IgG1 monoclonal antibody J Arora, JM Hickey, R Majumdar, R Esfandiary, SM Bishop, HS Samra, ... mAbs 7 (3), 525-539, 2015 | 75 | 2015 |
| Correlations between changes in conformational dynamics and physical stability in a mutant IgG1 mAb engineered for extended serum half-life R Majumdar, R Esfandiary, SM Bishop, HS Samra, CR Middaugh, ... mAbs 7 (1), 84-95, 2015 | 68 | 2015 |
John R. EngenJames L. Waters Chair & Distinguished Professor of Chemistry, Northeastern UniversityVerified email at neu.edu
