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Adrien Moreau
Adrien Moreau
PhyMedExp Montpellier
Verified email at ens-lyon.fr
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Cited by
Year
Biophysics, Pathophysiology and Pharmacology of Ion Channel Gating Pores
A Moreau, P Gosselin-Badaroudine, M Chahine
Pharmacology of Ion Channels and Channelopathies 5, 53, 2014
862014
Gating pore currents and the resting state of Nav1. 4 voltage sensor domains
P Gosselin-Badaroudine, L Delemotte, A Moreau, ML Klein, M Chahine
Proceedings of the National Academy of Sciences 109 (47), 19250-19255, 2012
812012
Gating pore currents are defects in common with two Nav1.5 mutations in patients with mixed arrhythmias and dilated cardiomyopathy
A Moreau, P Gosselin-Badaroudine, L Delemotte, ML Klein, M Chahine
Journal of General Physiology 145 (2), 93-106, 2015
802015
Post-translational modifications and diastolic calcium leak associated to the novel RyR2-D3638A mutation lead to CPVT in patient-specific hiPSC-derived cardiomyocytes
I Acimovic, MM Refaat, A Moreau, A Salykin, S Reiken, Y Sleiman, ...
Journal of clinical medicine 7 (11), 423, 2018
492018
Mutations in the voltage sensors of domains I and II of Nav1. 5 that are associated with arrhythmias and dilated cardiomyopathy generate gating pore currents
A Moreau, P Gosselin-Badaroudine, M Boutjdir, M Chahine
Frontiers in Pharmacology 6, 173259, 2015
432015
Nav1. 5 mutations linked to dilated cardiomyopathy phenotypes: Is the gating pore current the missing link?
P Gosselin-Badaroudine, A Moreau, M Chahine
Channels 8 (1), 90-94, 2014
372014
A leaky voltage sensor domain of cardiac sodium channels causes arrhythmias associated with dilated cardiomyopathy
A Moreau, P Gosselin-Badaroudine, A Mercier, B Burger, DI Keller, ...
Scientific reports 8 (1), 13804, 2018
342018
Mexiletine differentially restores the trafficking defects caused by two brugada syndrome mutations
A Moreau, DI Keller, H Huang, V Fressart, C Schmied, Q Timour, ...
Frontiers in Pharmacology 3, 62, 2012
332012
Biophysical, molecular, and pharmacological characterization of voltage-dependent sodium channels from induced pluripotent stem cell-derived cardiomyocytes
A Moreau, A Mercier, O Thériault, M Boutjdir, B Burger, DI Keller, ...
Canadian Journal of Cardiology 33 (2), 269-278, 2017
282017
Sodium overload due to a persistent current that attenuates the arrhythmogenic potential of a novel LQT3 mutation
A Moreau, AD Krahn, P Gosselin-Badaroudine, GJ Klein, G Christé, ...
Frontiers in pharmacology 4, 126, 2013
272013
Characterization of the honeybee AmNaV1 channel and tools to assess the toxicity of insecticides
P Gosselin-Badaroudine, A Moreau, L Delemotte, T Cens, C Collet, ...
Scientific Reports 5 (1), 12475, 2015
252015
Molecular biology and biophysical properties of ion channel gating pores
A Moreau, P Gosselin-Badaroudine, M Chahine
Quarterly reviews of biophysics 47 (4), 364-388, 2014
252014
A New Cardiac Channelopathy: From Clinical Phenotypes to Molecular Mechanisms Associated With Nav1.5 Gating Pores
A Moreau, M Chahine
Frontiers in cardiovascular medicine 5, 139, 2018
232018
Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca2+ channel subfamily: CaV4
P Gosselin-Badaroudine, A Moreau, L Simard, T Cens, M Rousset, ...
Journal of General Physiology 148 (2), 133-145, 2016
202016
Deciphering DSC2 arrhythmogenic cardiomyopathy electrical instability: From ion channels to ECG and tailored drug therapy
A Moreau, JB Reisqs, H Delanoe‐Ayari, M Pierre, A Janin, A Deliniere, ...
Clinical and translational medicine 11 (3), e319, 2021
192021
Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes
Y Sleiman, M Souidi, R Kumar, E Yang, F Jaffré, T Zhou, A Bernardin, ...
EBioMedicine 60, 2020
192020
Cardiac voltage-gated sodium channel mutations associated with left atrial dysfunction and stroke in children
A Moreau, A Janin, G Millat, P Chevalier
Ep Europace 20 (10), 1692-1698, 2018
172018
Gating pore currents in sodium channels
JR Groome, A Moreau, L Delemotte
Voltage-gated Sodium Channels: Structure, Function and Channelopathies, 371-399, 2018
162018
Novel SCN5A mutations in two families with “Brugada-like” ST elevation in the inferior leads and conduction disturbances
P Maury, A Moreau, F Hidden-Lucet, A Leenhardt, V Fressart, M Berthet, ...
Journal of Interventional Cardiac Electrophysiology 37, 131-140, 2013
142013
Gating pore currents, a new pathological mechanism underlying cardiac arrhythmias associated with dilated cardiomyopathy
A Moreau, P Gosselin-Badaroudine, M Chahine
Channels 9 (3), 139-144, 2015
132015
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