| Scavenger receptors in homeostasis and immunity J Canton, D Neculai, S Grinstein Nature Reviews Immunology 13 (9), 621-634, 2013 | 872 | 2013 |
| Structure of the dual enzyme Ire1 reveals the basis for catalysis and regulation in nonconventional RNA splicing KPK Lee, M Dey, D Neculai, C Cao, TE Dever, F Sicheri Cell 132 (1), 89-100, 2008 | 430 | 2008 |
| Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36 D Neculai, M Schwake, M Ravichandran, F Zunke, RF Collins, J Peters, ... Nature 504 (7478), 172-176, 2013 | 316 | 2013 |
| A strategy for modulation of enzymes in the ubiquitin system A Ernst, G Avvakumov, J Tong, Y Fan, Y Zhao, P Alberts, A Persaud, ... Science 339 (6119), 590-595, 2013 | 312 | 2013 |
| Suprafacial orientation of the SCFCdc4 dimer accommodates multiple geometries for substrate ubiquitination X Tang, S Orlicky, Z Lin, A Willems, D Neculai, D Ceccarelli, F Mercurio, ... Cell 129 (6), 1165-1176, 2007 | 251 | 2007 |
| An allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme DF Ceccarelli, X Tang, B Pelletier, S Orlicky, W Xie, V Plantevin, ... Cell 145 (7), 1075-1087, 2011 | 247 | 2011 |
| Elevated coding mutation rate during the reprogramming of human somatic cells into induced pluripotent stem cells J Ji, SH Ng, V Sharma, D Neculai, S Hussein, M Sam, Q Trinh, GM Church, ... Stem cells 30 (3), 435-440, 2012 | 212 | 2012 |
| Structure of the unphosphorylated STAT5a dimer D Neculai, AM Neculai, S Verrier, K Straub, K Klumpp, E Pfitzner, ... Journal of Biological Chemistry 280 (49), 40782-40787, 2005 | 178 | 2005 |
| Human cartilage-derived progenitor cells from committed chondrocytes for efficient cartilage repair and regeneration Y Jiang, Y Cai, W Zhang, Z Yin, C Hu, T Tong, P Lu, S Zhang, D Neculai, ... Stem Cells Translational Medicine 5 (6), 733-744, 2016 | 164 | 2016 |
| A novel assay uncovers an unexpected role for SR-BI in LDL transcytosis SM Armstrong, MG Sugiyama, KYY Fung, Y Gao, C Wang, AS Levy, ... Cardiovascular research 108 (2), 268-277, 2015 | 154 | 2015 |
| A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen Y Sheng, JH Hong, R Doherty, T Srikumar, J Shloush, GV Avvakumov, ... Molecular & Cellular Proteomics 11 (8), 329-341, 2012 | 134 | 2012 |
| Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export S Heybrock, K Kanerva, Y Meng, C Ing, A Liang, ZJ Xiong, X Weng, ... Nature communications 10 (1), 3521, 2019 | 132 | 2019 |
| Cholesterol handling in lysosomes and beyond Y Meng, S Heybrock, D Neculai, P Saftig Trends in cell biology 30 (6), 452-466, 2020 | 127 | 2020 |
| Preparation and Structure of the First Germanium(II) Hydroxide: The Congener of an Unknown Low‐Valent Carbon Analogue LW Pineda, V Jancik, HW Roesky, D Neculai, AM Neculai Angewandte Chemie International Edition 43 (11), 1419-1421, 2004 | 123 | 2004 |
| Palmitoylation of NOD1 and NOD2 is required for bacterial sensing Y Lu, Y Zheng, É Coyaud, C Zhang, A Selvabaskaran, Y Yu, Z Xu, ... Science 366 (6464), 460-467, 2019 | 117 | 2019 |
| Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machine DYL Mao, D Neculai, M Downey, S Orlicky, YZ Haffani, DF Ceccarelli, ... Molecular cell 32 (2), 259-275, 2008 | 107 | 2008 |
| Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells J Ji, V Sharma, S Qi, ME Guarch, P Zhao, Z Luo, W Fan, Y Wang, ... Stem cell reports 2 (1), 44-51, 2014 | 97 | 2014 |
| FAM 134B oligomerization drives endoplasmic reticulum membrane scission for ER‐phagy X Jiang, X Wang, X Ding, M Du, B Li, X Weng, J Zhang, L Li, R Tian, ... The EMBO journal 39 (5), e102608, 2020 | 95 | 2020 |
| Formation and Characterization of the First Monoalumoxane, LAlO⋅ B (C6F5) 3 D Neculai, HW Roesky, AM Neculai, J Magull, B Walfort, D Stalke Angewandte Chemie International Edition 41 (22), 4294-4296, 2002 | 94 | 2002 |
| The First Structurally Characterized Aluminum Compound with Two SH Groups:[LAl (SH) 2](L= N (Ar) C (Me) CHC (Me) N (Ar), Ar= 2, 6-i-Pr2C6H3) and the Catalytic Properties of the … V Jancik, Y Peng, HW Roesky, J Li, D Neculai, AM Neculai, ... Journal of the American Chemical Society 125 (6), 1452-1453, 2003 | 90 | 2003 |
Sergio GrinsteinSenior Scientist, Hospital for Sick Children, Cell Biology ProgramVerified email at sickkids.ca
