Posttranscriptional control of T cell effector function by aerobic glycolysis CH Chang, JD Curtis, LB Maggi, B Faubert, AV Villarino, D O’Sullivan, ... Cell 153 (6), 1239-1251, 2013 | 2236 | 2013 |
The JAK-STAT pathway: impact on human disease and therapeutic intervention JJ O'Shea, DM Schwartz, AV Villarino, M Gadina, IB McInnes, A Laurence Annual review of medicine 66 (1), 311-328, 2015 | 1548 | 2015 |
JAK inhibition as a therapeutic strategy for immune and inflammatory diseases DM Schwartz, Y Kanno, A Villarino, M Ward, M Gadina, JJ O'Shea Nature reviews Drug discovery 16 (12), 843-862, 2017 | 1280 | 2017 |
Interleukin 27 negatively regulates the development of interleukin 17–producing T helper cells during chronic inflammation of the central nervous system JS Stumhofer, A Laurence, EH Wilson, E Huang, CM Tato, LM Johnson, ... Nature immunology 7 (9), 937-945, 2006 | 1196 | 2006 |
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection AC Mullen, FA High, AS Hutchins, HW Lee, AV Villarino, DM Livingston, ... Science 292 (5523), 1907-1910, 2001 | 1172 | 2001 |
Mechanisms and consequences of Jak–STAT signaling in the immune system AV Villarino, Y Kanno, JJ O'Shea Nature immunology 18 (4), 374-384, 2017 | 1114 | 2017 |
An activating NLRC4 inflammasome mutation causes autoinflammation with recurrent macrophage activation syndrome SW Canna, AA de Jesus, S Gouni, SR Brooks, B Marrero, Y Liu, ... Nature genetics 46 (10), 1140-1146, 2014 | 771 | 2014 |
The IL-27R (WSX-1) is required to suppress T cell hyperactivity during infection A Villarino, L Hibbert, L Lieberman, E Wilson, T Mak, H Yoshida, ... Immunity 19 (5), 645-655, 2003 | 615 | 2003 |
Mechanisms of Jak/STAT signaling in immunity and disease AV Villarino, Y Kanno, JR Ferdinand, JJ O’Shea The Journal of Immunology 194 (1), 21-27, 2015 | 609 | 2015 |
Non-classical immunity controls microbiota impact on skin immunity and tissue repair JL Linehan, OJ Harrison, SJ Han, AL Byrd, I Vujkovic-Cvijin, AV Villarino, ... Cell 172 (4), 784-796. e18, 2018 | 414 | 2018 |
The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity D Artis, A Villarino, M Silverman, W He, EM Thornton, S Mu, S Summer, ... The Journal of Immunology 173 (9), 5626-5634, 2004 | 318 | 2004 |
Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease J Lohr, B Knoechel, JJ Wang, AV Villarino, AK Abbas The Journal of experimental medicine 203 (13), 2785-2791, 2006 | 306 | 2006 |
Understanding the pro-and anti-inflammatory properties of IL-27 AV Villarino, E Huang, CA Hunter The Journal of Immunology 173 (2), 715-720, 2004 | 306 | 2004 |
IL-27 limits IL-2 production during Th1 differentiation AV Villarino, JS Stumhofer, CJM Saris, RA Kastelein, FJ de Sauvage, ... The Journal of Immunology 176 (1), 237-247, 2006 | 297 | 2006 |
T cell activation induces proteasomal degradation of Argonaute and rapid remodeling of the microRNA repertoire Y Bronevetsky, AV Villarino, CJ Eisley, R Barbeau, AJ Barczak, GA Heinz, ... Journal of Experimental Medicine 210 (2), 417-432, 2013 | 231 | 2013 |
Positive and negative regulation of the IL-27 receptor during lymphoid cell activation AV Villarino, J Larkin, CJM Saris, AJ Caton, S Lucas, T Wong, ... The Journal of Immunology 174 (12), 7684-7691, 2005 | 215 | 2005 |
Distinct requirements for T-bet in gut innate lymphoid cells G Sciumè, K Hirahara, H Takahashi, A Laurence, AV Villarino, ... Journal of Experimental Medicine 209 (13), 2331-2338, 2012 | 192 | 2012 |
Helper T cell IL-2 production is limited by negative feedback and STAT-dependent cytokine signals AV Villarino, CM Tato, JS Stumhofer, Z Yao, YK Cui, L Hennighausen, ... The Journal of experimental medicine 204 (1), 65-71, 2007 | 164 | 2007 |
Asymmetric action of STAT transcription factors drives transcriptional outputs and cytokine specificity K Hirahara, A Onodera, AV Villarino, M Bonelli, G Sciumè, A Laurence, ... Immunity 42 (5), 877-889, 2015 | 163 | 2015 |
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency B Afzali, J Grönholm, J Vandrovcova, C O'Brien, HW Sun, I Vanderleyden, ... Nature immunology 18 (7), 813-823, 2017 | 148 | 2017 |