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Isha Sethi
Isha Sethi
Postdoctoral Fellow, Boston Children's Hospital and Dana Farber Cancer Institute
Verified email at jimmy.harvard.edu
Title
Cited by
Cited by
Year
Analysis of cardiac myocyte maturation using CASAAV, a platform for rapid dissection of cardiac myocyte gene function in vivo
Y Guo, NJ VanDusen, L Zhang, W Gu, I Sethi, S Guatimosim, Q Ma, ...
Circulation research 120 (12), 1874-1888, 2017
1172017
A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers
BN Akerberg, F Gu, NJ VanDusen, X Zhang, R Dong, K Li, B Zhang, ...
Nature communications 10 (1), 4907, 2019
1102019
A global analysis of the complex landscape of isoforms and regulatory networks of p63 in human cells and tissues
I Sethi, RA Romano, C Gluck, K Smalley, B Vojtesek, MJ Buck, S Sinha
BMC genomics 16, 1-15, 2015
752015
Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor
Y Guo, BD Jardin, P Zhou, I Sethi, BN Akerberg, CN Toepfer, Y Ai, Y Li, ...
Nature communications 9 (1), 3837, 2018
732018
Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling
Y Guo, Y Cao, BD Jardin, I Sethi, Q Ma, B Moghadaszadeh, EC Troiano, ...
Proceedings of the National Academy of Sciences 118 (2), e2008861118, 2021
452021
Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation
NJ VanDusen, JY Lee, W Gu, CE Butler, I Sethi, Y Zheng, JS King, P Zhou, ...
Nature communications 12 (1), 4442, 2021
402021
Role of chromatin and transcriptional co-regulators in mediating p63-genome interactions in keratinocytes
I Sethi, S Sinha, MJ Buck
BMC genomics 15, 1-17, 2014
392014
Evolutionary re-wiring of p63 and the epigenomic regulatory landscape in keratinocytes and its potential implications on species-specific gene expression and phenotypes
I Sethi, C Gluck, H Zhou, MJ Buck, S Sinha
Nucleic acids research 45 (14), 8208-8224, 2017
382017
Reactivation of super-enhancers by KLF4 in human Head and Neck Squamous Cell Carcinoma
M Tsompana, C Gluck, I Sethi, I Joshi, J Bard, NJ Nowak, S Sinha, ...
Oncogene 39 (2), 262-277, 2020
172020
GATA4 regulates developing endocardium through interaction with ETS1
P Zhou, Y Zhang, I Sethi, L Ye, MA Trembley, Y Cao, BN Akerberg, F Xiao, ...
Circulation research 131 (11), e152-e168, 2022
92022
Molecular profiling establishes genetic features predictive of the efficacy of the p110β inhibitor KIN-193
I Sethi, Z Cai, TM Roberts, GC Yuan
Cancer research 79 (17), 4524-4531, 2019
72019
Blocking PI3K p110β Attenuates Development of PTEN-Deficient Castration-Resistant Prostate Cancer
X Gao, Y Wang, CF Ribeiro, C Manokaran, H Chang, T Von, S Rodrigues, ...
Molecular Cancer Research 20 (5), 673-685, 2022
62022
Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation
P Zhou, NJ VanDusen, Y Zhang, Y Cao, I Sethi, R Hu, S Zhang, G Wang, ...
Developmental Cell 58 (10), 898-914. e7, 2023
52023
Spatial mapping of human hematopoiesis at single-cell resolution reveals aging-associated topographic remodeling
A Sarachakov, A Varlamova, V Svekolkin, M Polyakova, I Valencia, ...
Blood 142 (26), 2282-2295, 2023
32023
Sarcomeres regulate cardiomyocyte maturation through MRTF-SRF signaling
Y Guo, BD Jardin, I Sethi, Q Ma, B Moghadaszadeh, EC Troiano, ...
bioRxiv, 824185, 2019
32019
An integrated genomic approach identifies follistatin as a target of the p63-epidermal growth factor receptor oncogenic network in head and neck squamous cell carcinoma
A Oyelakin, J Sosa, KB Nayak, A Glathar, C Gluck, I Sethi, M Tsompana, ...
NAR cancer 5 (3), zcad038, 2023
12023
Transcriptomic-Based Microenvironment Classification Reveals Precision Medicine Strategies for PDAC
B George, O Kudryashova, A Kravets, S Thalji, S Malarkannan, ...
Gastroenterology, 2024
2024
Single Cell Resolution Spatial Mapping of Human Hematopoiesis Reveals Aging-Associated Topographic Remodeling
A Sarachakov, A Varlamova, V Svekolkin, I Galkin, I Valencia, ...
bioRxiv, 2023.04. 28.538715, 2023
2023
Mutual Potentiation Between Myofibril Assembly and Serum Response Factor in Cardiomyocyte Maturation
Y Guo, B Jardin, I Sethi, B Moghadaszadeh, A Beggs, W Pu
Circulation Research 125 (Suppl_1), A920-A920, 2019
2019
RNF20/40 Regulates Cardiomyocyte Maturation
NJ Vandusen, JY Lee, W Gu, I Sethi, S Suo, J King, Y Zheng, Y Guo, ...
Circulation Research 125 (Suppl_1), A658-A658, 2019
2019
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Articles 1–20