| Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal-and glyoxal-glycated cysteine, arginine, and lysine residues G Richarme, M Mihoub, J Dairou, LC Bui, T Leger, A Lamouri Journal of Biological Chemistry 290 (3), 1885-1897, 2015 | 257 | 2015 |
| The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells G Barbet, M Demion, IC Moura, N Serafini, T Léger, F Vrtovsnik, ... Nature immunology 9 (10), 1148-1156, 2008 | 222 | 2008 |
| Guanine glycation repair by DJ-1/Park7 and its bacterial homologs G Richarme, C Liu, M Mihoub, J Abdallah, T Leger, N Joly, JC Liebart, ... Science 357 (6347), 208-211, 2017 | 160 | 2017 |
| Yersinia pseudotuberculosis effector YopJ subverts the Nod2/RICK/TAK1 pathway and activates caspase-1 to induce intestinal barrier dysfunction U Meinzer, F Barreau, S Esmiol-Welterlin, C Jung, C Villard, T Leger, ... Cell host & microbe 11 (4), 337-351, 2012 | 142 | 2012 |
| Transportin-1 binds to the HIV-1 capsid via a nuclear localization signal and triggers uncoating J Fernandez, AK Machado, S Lyonnais, C Chamontin, K Gärtner, T Léger, ... Nature microbiology 4 (11), 1840-1850, 2019 | 106 | 2019 |
| A comparative study of iron uptake mechanisms in marine microalgae: iron binding at the cell surface is a critical step R Sutak, H Botebol, PL Blaiseau, T Léger, FY Bouget, JM Camadro, ... Plant physiology 160 (4), 2271-2284, 2012 | 99 | 2012 |
| Proteomics profiling of urine reveals specific titin fragments as biomarkers of Duchenne muscular dystrophy J Rouillon, A Zocevic, T Leger, C Garcia, JM Camadro, B Udd, B Wong, ... Neuromuscular Disorders 24 (7), 563-573, 2014 | 94 | 2014 |
| Imaging mass spectrometry reveals modified forms of histone H4 as new biomarkers of microvascular invasion in hepatocellular carcinomas N Poté, T Alexandrov, J Le Faouder, S Laouirem, T Léger, M Mebarki, ... Hepatology 58 (3), 983-994, 2013 | 92 | 2013 |
| Homocysteinylation of neuronal proteins contributes to folate deficiency‐associated alterations of differentiation, vesicular transport, and plasticity in hippocampal neuronal … N Akchiche, C Bossenmeyer‐Pourié, R Kerek, N Martin, G Pourié, ... The FASEB Journal 26 (10), 3980-3992, 2012 | 83 | 2012 |
| Osteopontin and the dento-osseous pathobiology of X-linked hypophosphatemia T Boukpessi, B Hoac, BR Coyac, T Leger, C Garcia, P Wicart, MP Whyte, ... Bone 95, 151-161, 2017 | 74 | 2017 |
| Salivary proteome modifications associated with periodontitis in obese patients H Rangé, T Léger, C Huchon, C Ciangura, D Diallo, C Poitou, O Meilhac, ... Journal of clinical periodontology 39 (9), 799-806, 2012 | 69 | 2012 |
| Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies J Rouillon, J Poupiot, A Zocevic, F Amor, T Léger, C Garcia, JM Camadro, ... Human molecular genetics 24 (17), 4916-4932, 2015 | 66 | 2015 |
| LGP2 binds to PACT to regulate RIG-I–and MDA5-mediated antiviral responses RY Sanchez David, C Combredet, V Najburg, GA Millot, G Beauclair, ... Science signaling 12 (601), eaar3993, 2019 | 62 | 2019 |
| Metabolomic and proteomic investigations of impacts of titanium dioxide nanoparticles on Escherichia coli M Planchon, T Léger, O Spalla, G Huber, R Ferrari PLoS One 12 (6), e0178437, 2017 | 61 | 2017 |
| Central role for ferritin in the day/night regulation of iron homeostasis in marine phytoplankton H Botebol, E Lesuisse, R Šuták, C Six, JC Lozano, P Schatt, V Vergé, ... Proceedings of the National Academy of Sciences 112 (47), 14652-14657, 2015 | 60 | 2015 |
| The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans T Léger, C Garcia, M Ounissi, G Lelandais, JM Camadro Molecular & Cellular Proteomics 14 (1), 93-108, 2015 | 58 | 2015 |
| Insights into brain glycogen metabolism: the structure of human brain glycogen phosphorylase C Mathieu, IL de La Sierra-Gallay, R Duval, X Xu, A Cocaign, T Léger, ... Journal of Biological Chemistry 291 (35), 18072-18083, 2016 | 57 | 2016 |
| Sumoylation of the THO complex regulates the biogenesis of a subset of mRNPs H Bretes, JO Rouviere, T Leger, M Oeffinger, F Devaux, V Doye, ... Nucleic acids research 42 (8), 5043-5058, 2014 | 56 | 2014 |
| Cdk1 phosphorylates SPAT-1/Bora to trigger PLK-1 activation and drive mitotic entry in C. elegans embryos N Tavernier, A Noatynska, C Panbianco, L Martino, L Van Hove, ... Journal of Cell Biology 208 (6), 661-669, 2015 | 50 | 2015 |
| AAV-8 and AAV-9 vectors cooperate with serum proteins differently than AAV-1 and AAV-6 J Denard, J Rouillon, T Leger, C Garcia, MP Lambert, G Griffith, C Jenny, ... Molecular Therapy-Methods & Clinical Development 10, 291-302, 2018 | 43 | 2018 |
