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Laura den Hartigh
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Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease
A Chait, LJ Den Hartigh
Frontiers in cardiovascular medicine 7, 522637, 2020
9522020
Triglyceride-rich lipoprotein lipolysis releases neutral and oxidized FFAs that induce endothelial cell inflammation
L Wang, R Gill, TL Pedersen, LJ Higgins, JW Newman, JC Rutledge
Journal of lipid research 50 (2), 204-213, 2009
4342009
Conjugated linoleic acid effects on cancer, obesity, and atherosclerosis: A review of pre-clinical and human trials with current perspectives
LJ den Hartigh
Nutrients 11 (2), 370, 2019
2922019
NADPH oxidase-derived reactive oxygen species increases expression of monocyte chemotactic factor genes in cultured adipocytes
CY Han, T Umemoto, M Omer, LJ Den Hartigh, T Chiba, R LeBoeuf, ...
Journal of Biological Chemistry 287 (13), 10379-10393, 2012
1962012
Apolipoprotein AI and high-density lipoprotein have anti-inflammatory effects on adipocytes via cholesterol transporters: ATP-binding cassette A-1, ATP-binding cassette G-1 …
T Umemoto, CY Han, P Mitra, MM Averill, C Tang, L Goodspeed, M Omer, ...
Circulation research 112 (10), 1345-1354, 2013
1332013
Adipocyte-specific deficiency of NADPH oxidase 4 delays the onset of insulin resistance and attenuates adipose tissue inflammation in obesity
LJ Den Hartigh, M Omer, L Goodspeed, S Wang, T Wietecha, KD O’Brien, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (3), 466-475, 2017
1062017
Fatty acids from very low-density lipoprotein lipolysis products induce lipid droplet accumulation in human monocytes
LJ den Hartigh, JE Connolly-Rohrbach, S Fore, TR Huser, JC Rutledge
The Journal of Immunology 184 (7), 3927-3936, 2010
1052010
Endotoxin and polycyclic aromatic hydrocarbons in ambient fine particulate matter from Fresno, California initiate human monocyte inflammatory responses mediated by reactive …
LJ Den Hartigh, MW Lamé, W Ham, MJ Kleeman, F Tablin, DW Wilson
Toxicology in Vitro 24 (7), 1993-2002, 2010
772010
Obese mice losing weight due to trans-10, cis-12 conjugated linoleic acid supplementation or food restriction harbor distinct gut microbiota
LJ den Hartigh, Z Gao, L Goodspeed, S Wang, AK Das, CF Burant, ...
The Journal of nutrition 148 (4), 562-572, 2018
762018
Deletion of serum amyloid A3 improves high fat high sucrose diet-induced adipose tissue inflammation and hyperlipidemia in female mice
LJ den Hartigh, S Wang, L Goodspeed, Y Ding, M Averill, S Subramanian, ...
PLoS One 9 (9), e108564, 2014
662014
Postprandial VLDL lipolysis products increase monocyte adhesion and lipid droplet formation via activation of ERK2 and NFκB
LJ den Hartigh, R Altman, JE Norman, JC Rutledge
American Journal of Physiology-Heart and Circulatory Physiology 306 (1 …, 2014
602014
10E, 12Z-conjugated linoleic acid impairs adipocyte triglyceride storage by enhancing fatty acid oxidation, lipolysis, and mitochondrial reactive oxygen species
LJ den Hartigh, CY Han, S Wang, M Omer, A Chait
Journal of lipid research 54 (11), 2964-2978, 2013
602013
Serum amyloid A3 is a high density lipoprotein-associated acute-phase protein
LR Tannock, MC De Beer, A Ji, P Shridas, VP Noffsinger, L den Hartigh, ...
Journal of lipid research 59 (2), 339-347, 2018
482018
Adipocyte-derived versican and macrophage-derived biglycan control adipose tissue inflammation in obesity
CY Han, I Kang, IA Harten, JA Gebe, CK Chan, M Omer, KM Alonge, ...
Cell reports 31 (13), 2020
412020
Metabolically distinct weight loss by 10, 12 CLA and caloric restriction highlight the importance of subcutaneous white adipose tissue for glucose homeostasis in mice
LJ den Hartigh, S Wang, L Goodspeed, T Wietecha, B Houston, M Omer, ...
PLoS One 12 (2), e0172912, 2017
392017
Inflammation associated with the postprandial lipolysis of triglyceriderich lipoproteins by lipoprotein lipase
LJ Higgins, JC Rutledge
Current atherosclerosis reports 11 (3), 199-205, 2009
372009
T cell activation inhibitors reduce CD8+ T cell and pro-inflammatory macrophage accumulation in adipose tissue of obese mice
VN Montes, MS Turner, S Subramanian, Y Ding, M Hayden-Ledbetter, ...
PLoS One 8 (7), e67709, 2013
362013
Modulation of adipocyte metabolism by microbial short-chain fatty acids
KS May, LJ den Hartigh
Nutrients 13 (10), 3666, 2021
322021
Lipid-cell interactions in human monocytes investigated by doubly-resonant coherent anti-Stokes Raman scattering microscopy
T Weeks, I Schie, LJ den Hartigh, JC Rutledge, T Huser
Journal of biomedical optics 16 (2), 021117-021117-5, 2011
302011
Chronic oral rapamycin decreases adiposity, hepatic triglycerides and insulin resistance in male mice fed a diet high in sucrose and saturated fat
LJ den Hartigh, L Goodspeed, SA Wang, HL Kenerson, M Omer, ...
Experimental physiology 103 (11), 1469-1480, 2018
272018
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