| DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells S Jahr, H Hentze, S Englisch, D Hardt, FO Fackelmayer, RD Hesch, ... Cancer research 61 (4), 1659-1665, 2001 | 2830 | 2001 |
| Teratoma formation by human embryonic stem cells: evaluation of essential parameters for future safety studies H Hentze, PL Soong, ST Wang, BW Phillips, TC Putti, NR Dunn Stem cell research 2 (3), 198-210, 2009 | 564 | 2009 |
| Selection against undifferentiated human embryonic stem cells by a cytotoxic antibody recognizing podocalyxin-like protein-1 AB Choo, HL Tan, SN Ang, WJ Fong, A Chin, J Lo, L Zheng, H Hentze, ... Stem cells 26 (6), 1454-1463, 2008 | 312 | 2008 |
| The generation of six clinical-grade human embryonic stem cell lines JM Crook, TT Peura, L Kravets, AG Bosman, JJ Buzzard, R Horne, ... Cell stem cell 1 (5), 490-494, 2007 | 257 | 2007 |
| Cell therapy and the safety of embryonic stem cell-derived grafts H Hentze, R Graichen, A Colman Trends in biotechnology 25 (1), 24-32, 2007 | 248 | 2007 |
| Critical role for cathepsin B in mediating caspase-1-dependent interleukin-18 maturation and caspase-1-independent necrosis triggered by the microbial toxin nigericin H Hentze, XY Lin, MSK Choi, AG Porter Cell Death & Differentiation 10 (9), 956-968, 2003 | 232 | 2003 |
| SB1518, a novel macrocyclic pyrimidine-based JAK2 inhibitor for the treatment of myeloid and lymphoid malignancies S Hart, KC Goh, V Novotny-Diermayr, CY Hu, H Hentze, YC Tan, B Madan, ... Leukemia 25 (11), 1751-1759, 2011 | 208 | 2011 |
| Directed differentiation of human embryonic stem cells into the pancreatic endocrine lineage BW Phillips, H Hentze, WL Rust, QP Chen, H Chipperfield, EK Tan, ... Stem cells and development 16 (4), 561-578, 2007 | 179 | 2007 |
| Apoptosis in the absence of poly-(ADP-ribose) polymerase M Leist, B Single, G Künstle, C Volbracht, H Hentze, P Nicotera Biochemical and biophysical research communications 233 (2), 518-522, 1997 | 167 | 1997 |
| SB939, a novel potent and orally active histone deacetylase inhibitor with high tumor exposure and efficacy in mouse models of colorectal cancer V Novotny-Diermayr, K Sangthongpitag, CY Hu, X Wu, N Sausgruber, ... Molecular cancer therapeutics 9 (3), 642-652, 2010 | 148 | 2010 |
| Concanavalin A hepatotoxicity in mice: Tumor necrosis factor–mediated organ failure independent of caspase‐3–like protease activation G Künstle, H Hentze, PG Germann, G Tiegs, T Meergans, A Wendel Hepatology 30 (5), 1241-1251, 1999 | 124 | 1999 |
| Ajoene, an experimental anti-leukemic drug: mechanism of cell death VM Dirsch, DSM Antlsperger, H Hentze, AM Vollmar Leukemia 16 (1), 74-83, 2002 | 114 | 2002 |
| The oral HDAC inhibitor pracinostat (SB939) is efficacious and synergistic with the JAK2 inhibitor pacritinib (SB1518) in preclinical models of AML V Novotny-Diermayr, S Hart, KC Goh, A Cheong, LC Ong, H Hentze, ... Blood cancer journal 2 (5), e69-e69, 2012 | 111 | 2012 |
| Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice H Hentze, F Gantner, SA Kolb, A Wendel The American Journal of Pathology 156 (6), 2045-2056, 2000 | 99 | 2000 |
| CD95‐mediated murine hepatic apoptosis requires an intact glutathione status H Hentze, G Künstle, C Volbracht, W Ertel, A Wendel Hepatology 30 (1), 177-185, 1999 | 91 | 1999 |
| The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal … CEZ Chan, SGK Seah, DH Chye, S Massey, M Torres, APC Lim, ... PLoS One 16 (6), e0253487, 2021 | 89 | 2021 |
| Glutathione dependence of caspase-8 activation at the death-inducing signaling complex H Hentze, I Schmitz, M Latta, A Krueger, PH Krammer, A Wendel Journal of Biological Chemistry 277 (7), 5588-5595, 2002 | 89 | 2002 |
| Phenotype-driven precision oncology as a guide for clinical decisions one patient at a time S Chia, JL Low, X Zhang, XL Kwang, FT Chong, A Sharma, D Bertrand, ... Nature communications 8 (1), 435, 2017 | 84 | 2017 |
| The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy M Leist, S Bremer, P Brundin, J Hescheler, A Kirkeby, KH Krause, ... | 84 | 2008 |
| Caspase-3 activity is present in cerebrospinal fluid from patients with traumatic brain injury L Härter, M Keel, H Hentze, M Leist, W Ertel Journal of neuroimmunology 121 (1-2), 76-78, 2001 | 76 | 2001 |
N. Ray DunnPrincipal Investigator, Institute of Medical BiologyVerified email at imb.a-star.edu.sg
