Jan Gruber
Jan Gruber
Associate Professor, Yale-NUS College and National University of Singapore
Verified email at
Cited by
Cited by
Developments in the CCP4 molecular-graphics project
L Potterton, S McNicholas, E Krissinel, J Gruber, K Cowtan, P Emsley, ...
Acta Crystallographica Section D: Biological Crystallography 60 (12), 2288-2294, 2004
The mitochondrial free radical theory of ageing—where do we stand
J Gruber, S Schaffer, B Halliwell
Front Biosci 13 (17), 6554-6579, 2008
Evidence for a Trade‐Off between Survival and Fitness Caused by Resveratrol Treatment of Caenorhabditis elegans
JAN Gruber, SY Tang, B Halliwell
Annals of the New York Academy of Sciences 1100 (1), 530-542, 2007
WNT signaling in disease
LF Ng, P Kaur, N Bunnag, J Suresh, ICH Sung, QH Tan, J Gruber, ...
Cells 8 (8), 826, 2019
Isoindolinone inhibitors of the murine double minute 2 (MDM2)-p53 protein− protein interaction: structure− activity studies leading to improved potency
IR Hardcastle, J Liu, E Valeur, A Watson, SU Ahmed, TJ Blackburn, ...
Journal of medicinal chemistry 54 (5), 1233-1243, 2011
The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease
LF Ng, J Gruber, IK Cheah, CK Goo, WF Cheong, G Shui, KP Sit, ...
Free Radical Biology and Medicine 71, 390-401, 2014
Mitochondria-targeted antioxidants and metabolic modulators as pharmacological interventions to slow ageing
J Gruber, S Fong, CB Chen, S Yoong, G Pastorin, S Schaffer, I Cheah, ...
Biotechnology advances 31 (5), 563-592, 2013
Is uric acid protective or deleterious in acute ischemic stroke? A prospective cohort study
RCS Seet, K Kasiman, J Gruber, SY Tang, MC Wong, HM Chang, ...
Atherosclerosis 209 (1), 215-219, 2010
The DrugAge database of aging‐related drugs
D Barardo, D Thornton, H Thoppil, M Walsh, S Sharifi, S Ferreira, A Anžič, ...
Aging cell 16 (3), 594-597, 2017
Deceptively simple but simply deceptive–Caenorhabditis elegans lifespan studies: considerations for aging and antioxidant effects
J Gruber, LF Ng, SK Poovathingal, B Halliwell
FEBS letters 583 (21), 3377-3387, 2009
Ageing in nematodes: do antioxidants extend lifespan in Caenorhabditis elegans?
PBL Pun, J Gruber, SY Tang, S Schaffer, RLS Ong, S Fong, LF Ng, ...
Biogerontology 11, 17-30, 2010
Hydrogen Sulfide Is an Endogenous Regulator of Aging in Caenorhabditis elegans
B Qabazard, L Li, J Gruber, MT Peh, LF Ng, SD Kumar, P Rose, CH Tan, ...
Antioxidants & redox signaling 20 (16), 2621-2630, 2014
Mitochondrial changes in ageing Caenorhabditis elegans–what do we learn from superoxide dismutase knockouts?
J Gruber, LF Ng, S Fong, YT Wong, SA Koh, CB Chen, G Shui, ...
PloS one 6 (5), e19444, 2011
Energy crisis precedes global metabolic failure in a novel Caenorhabditis elegans Alzheimer Disease model
S Fong, E Teo, LF Ng, CB Chen, LN Lakshmanan, SY Tsoi, PK Moore, ...
Scientific reports 6 (1), 33781, 2016
Elevation of oxidative-damage biomarkers during aging in F2 hybrid mice: protection by chronic oral intake of resveratrol
YT Wong, J Gruber, AM Jenner, MPE Ng, R Ruan, FEH Tay
Free Radical Biology and Medicine 46 (6), 799-809, 2009
Drug synergy slows aging and improves healthspan through IGF and SREBP lipid signaling
TD Admasu, KC Batchu, D Barardo, LF Ng, VYM Lam, L Xiao, ...
Developmental Cell 47 (1), 67-79. e5, 2018
Allantoin in Human Plasma, Serum, and Nasal-Lining Fluids as a Biomarker of Oxidative Stress: Avoiding Artifacts and Establishing Real in vivo Concentrations
J Gruber, SY Tang, AM Jenner, I Mudway, A Blomberg, A Behndig, ...
Antioxidants & redox signaling 11 (8), 1767-1776, 2009
Lack of blinding of outcome assessors in animal model experiments implies risk of observer bias
S Bello, LT Krogsb°ll, J Gruber, ZJ Zhao, D Fischer, A Hrˇbjartsson
Journal of clinical epidemiology 67 (9), 973-983, 2014
The effect of dichloroacetate on health- and lifespan in C. elegans
S Schaffer, J Gruber, LF Ng, S Fong, YT Wong, SY Tang, B Halliwell
Biogerontology 12, 195-209, 2011
Developmental drift and the role of Wnt signaling in aging
J Gruber, Z Yee, NS Tolwinski
Cancers 8 (8), 73, 2016
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