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David Frederick
David Frederick
Postdoctoral fellow, Perelman School of Medicine, University of Pennsylvania
Verified email at mail.med.upenn.edu
Title
Cited by
Cited by
Year
Quantitative analysis of NAD synthesis-breakdown fluxes
L Liu, X Su, WJ Quinn, S Hui, K Krukenberg, DW Frederick, P Redpath, ...
Cell metabolism 27 (5), 1067-1080. e5, 2018
4332018
Effects of sex, strain, and energy intake on hallmarks of aging in mice
SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen, E Fang, M Aon, ...
Cell metabolism 23 (6), 1093-1112, 2016
4102016
SirT1 regulates adipose tissue inflammation
MP Gillum, ME Kotas, DM Erion, R Kursawe, P Chatterjee, KT Nead, ...
Diabetes 60 (12), 3235-3245, 2011
3372011
Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle
DW Frederick, E Loro, L Liu, A Davila, K Chellappa, IM Silverman, ...
Cell metabolism 24 (2), 269-282, 2016
3282016
Nicotinamide improves aspects of healthspan, but not lifespan, in mice
SJ Mitchell, M Bernier, MA Aon, S Cortassa, EY Kim, EF Fang, ...
Cell metabolism 27 (3), 667-676. e4, 2018
3042018
A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain
FR Jornayvaz, MJ Jurczak, HY Lee, AL Birkenfeld, DW Frederick, ...
American Journal of Physiology-Endocrinology and Metabolism 299 (5), E808-E815, 2010
2452010
SGLT2 deletion improves glucose homeostasis and preserves pancreatic β-cell function
MJ Jurczak, HY Lee, AL Birkenfeld, FR Jornayvaz, DW Frederick, ...
Diabetes 60 (3), 890-898, 2011
2402011
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice
AL Birkenfeld, HY Lee, F Guebre-Egziabher, TC Alves, MJ Jurczak, ...
Cell metabolism 14 (2), 184-195, 2011
2022011
Deletion of the α-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity
WA Chutkow, AL Birkenfeld, JD Brown, HY Lee, DW Frederick, ...
Diabetes 59 (6), 1424-1434, 2010
1832010
N-acylphosphatidylethanolamine, a gut-derived circulating factor induced by fat ingestion, inhibits food intake
MP Gillum, D Zhang, XM Zhang, DM Erion, RA Jamison, C Choi, J Dong, ...
Cell 135 (5), 813-824, 2008
1682008
Apolipoprotein CIII overexpressing mice are predisposed to diet‐induced hepatic steatosis and hepatic insulin resistance
HY Lee, AL Birkenfeld, FR Jornayvaz, MJ Jurczak, S Kanda, V Popov, ...
Hepatology 54 (5), 1650-1660, 2011
1332011
Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism
DW Frederick, JG Davis, A Dávila, B Agarwal, S Michan, MA Puchowicz, ...
Journal of Biological Chemistry 290 (3), 1546-1558, 2015
1002015
Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism
DW Frederick, JG Davis, A Dávila, B Agarwal, S Michan, MA Puchowicz, ...
Journal of Biological Chemistry 290 (3), 1546-1558, 2015
1002015
Influence of the hepatic eukaryotic initiation factor 2α (eIF2α) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral …
AL Birkenfeld, HY Lee, S Majumdar, MJ Jurczak, JP Camporez, ...
Journal of Biological Chemistry 286 (42), 36163-36170, 2011
822011
Influence of the hepatic eukaryotic initiation factor 2α (eIF2α) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral …
AL Birkenfeld, HY Lee, S Majumdar, MJ Jurczak, JP Camporez, ...
Journal of Biological Chemistry 286 (42), 36163-36170, 2011
822011
Rapamycin blocks induction of the thermogenic program in white adipose tissue
CM Tran, S Mukherjee, L Ye, DW Frederick, M Kissig, JG Davis, ...
Diabetes 65 (4), 927-941, 2016
812016
Rapamycin maintains NAD+/NADH redox homeostasis in muscle cells
Z Zhang, HN Xu, S Li, A Davila Jr, K Chellappa, JG Davis, Y Guan, ...
Aging (albany NY) 12 (18), 17786, 2020
222020
Complementary NAD+ replacement strategies fail to functionally protect dystrophin-deficient muscle
DW Frederick, AV McDougal, M Semenas, J Vappiani, A Nuzzo, JC Ulrich, ...
Skeletal Muscle 10, 1-14, 2020
202020
Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics?
NM Doliba, Q Liu, C Li, J Chen, P Chen, C Liu, DW Frederick, JA Baur, ...
Molecular metabolism 4 (12), 926-939, 2015
162015
Stable isotope labeling by essential nutrients in cell culture (SILEC) for accurate measurement of nicotinamide adenine dinucleotide metabolism
DW Frederick, S Trefely, A Buas, J Goodspeed, J Singh, C Mesaros, ...
Analyst 142 (23), 4431-4437, 2017
112017
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