| Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine S Ito, L Shen, Q Dai, SC Wu, LB Collins, JA Swenberg, C He, Y Zhang Science 333 (6047), 1300-1303, 2011 | 3996 | 2011 |
| Distinct epigenomic landscapes of pluripotent and lineage-committed human cells RD Hawkins, GC Hon, LK Lee, QM Ngo, R Lister, M Pelizzola, LE Edsall, ... Cell stem cell 6 (5), 479-491, 2010 | 1002 | 2010 |
| Genome-wide analysis reveals TET-and TDG-dependent 5-methylcytosine oxidation dynamics L Shen, H Wu, D Diep, S Yamaguchi, AC D’Alessio, HL Fung, K Zhang, ... Cell 153 (3), 692-706, 2013 | 587 | 2013 |
| Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation S Matoba, Y Liu, F Lu, KA Iwabuchi, L Shen, A Inoue, Y Zhang Cell 159 (4), 884-895, 2014 | 510 | 2014 |
| Mechanism and function of oxidative reversal of DNA and RNA methylation L Shen, CX Song, C He, Y Zhang Annual review of biochemistry 83 (1), 585-614, 2014 | 387 | 2014 |
| AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation CS Nabel, H Jia, Y Ye, L Shen, HL Goldschmidt, JT Stivers, Y Zhang, ... Nature chemical biology 8 (9), 751-758, 2012 | 384 | 2012 |
| Tet1 controls meiosis by regulating meiotic gene expression S Yamaguchi, K Hong, R Liu, L Shen, A Inoue, D Diep, K Zhang, Y Zhang Nature 492 (7429), 443-447, 2012 | 366 | 2012 |
| Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes J He, L Shen, M Wan, O Taranova, H Wu, Y Zhang Nature cell biology 15 (4), 373-384, 2013 | 352 | 2013 |
| Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development A Inoue, L Shen, Q Dai, C He, Y Zhang Cell research 21 (12), 1670-1676, 2011 | 322 | 2011 |
| Role of Tet1 in erasure of genomic imprinting S Yamaguchi, L Shen, Y Liu, D Sendler, Y Zhang Nature 504 (7480), 460-464, 2013 | 283 | 2013 |
| Tet3 and DNA replication mediate demethylation of both the maternal and paternal genomes in mouse zygotes L Shen, A Inoue, J He, Y Liu, F Lu, Y Zhang Cell stem cell 15 (4), 459-471, 2014 | 275 | 2014 |
| Rapamycin and other longevity‐promoting compounds enhance the generation of mouse induced pluripotent stem cells T Chen, L Shen, J Yu, H Wan, A Guo, J Chen, Y Long, J Zhao, G Pei Aging cell 10 (5), 908-911, 2011 | 246 | 2011 |
| Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming S Yamaguchi, K Hong, R Liu, A Inoue, L Shen, K Zhang, Y Zhang Cell research 23 (3), 329-339, 2013 | 212 | 2013 |
| HER2 recruits AKT1 to disrupt STING signalling and suppress antiviral defence and antitumour immunity S Wu, Q Zhang, F Zhang, F Meng, S Liu, R Zhou, Q Wu, X Li, LI Shen, ... Nature cell biology 21 (8), 1027-1040, 2019 | 210 | 2019 |
| Single-base resolution analysis of active DNA demethylation using methylase-assisted bisulfite sequencing H Wu, X Wu, L Shen, Y Zhang Nature biotechnology 32 (12), 1231-1240, 2014 | 165 | 2014 |
| 5-Hydroxymethylcytosine: generation, fate, and genomic distribution L Shen, Y Zhang Current opinion in cell biology 25 (3), 289-296, 2013 | 165 | 2013 |
| A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis D Zhang, Y Liu, Y Zhu, Q Zhang, H Guan, S Liu, S Chen, C Mei, C Chen, ... Nature cell biology 24 (5), 766-782, 2022 | 151 | 2022 |
| Loss of H3K27me3 imprinting in somatic cell nuclear transfer embryos disrupts post-implantation development S Matoba, H Wang, L Jiang, F Lu, KA Iwabuchi, X Wu, K Inoue, L Yang, ... Cell stem cell 23 (3), 343-354. e5, 2018 | 147 | 2018 |
| Direct generation of human neuronal cells from adult astrocytes by small molecules L Gao, W Guan, M Wang, H Wang, J Yu, Q Liu, B Qiu, Y Yu, Y Ping, ... Stem cell reports 8 (3), 538-547, 2017 | 130 | 2017 |
| Itaconate inhibits TET DNA dioxygenases to dampen inflammatory responses LL Chen, C Morcelle, ZL Cheng, X Chen, Y Xu, Y Gao, J Song, Z Li, ... Nature cell biology 24 (3), 353-363, 2022 | 124 | 2022 |
