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Sean Marrache
Sean Marrache
Senior Scientist, 10x Genomics
Verified email at 10xgenomics.com - Homepage
Title
Cited by
Cited by
Year
Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics
S Marrache, S Dhar
Proceedings of the National Academy of Sciences 109 (40), 16288-16293, 2012
4932012
The Prodrug Platin‐A: Simultaneous Release of Cisplatin and Aspirin
RK Pathak, S Marrache, JH Choi, TB Berding, S Dhar
Angewandte Chemie International Edition 53 (7), 1963-1967, 2014
2592014
Detouring of cisplatin to access mitochondrial genome for overcoming resistance
S Marrache, RK Pathak, S Dhar
Proceedings of the National Academy of Sciences 111 (29), 10444-10449, 2014
2342014
Biodegradable synthetic high-density lipoprotein nanoparticles for atherosclerosis
S Marrache, S Dhar
Proceedings of the National Academy of Sciences 110 (23), 9445-9450, 2013
1432013
Mito-DCA: a mitochondria targeted molecular scaffold for efficacious delivery of metabolic modulator dichloroacetate
RK Pathak, S Marrache, DA Harn, S Dhar
ACS chemical biology 9 (5), 1178-1187, 2014
1332014
Ex Vivo Programming of Dendritic Cells by Mitochondria-Targeted Nanoparticles to Produce Interferon-Gamma for Cancer Immunotherapy
S Marrache, S Tundup, DA Harn, S Dhar
ACS nano 7 (8), 7392-7402, 2013
1312013
The energy blocker inside the power house: Mitochondria targeted delivery of 3-bromopyruvate
S Marrache, S Dhar
Chemical science 6 (3), 1832-1845, 2015
972015
Immune stimulating photoactive hybrid nanoparticles for metastatic breast cancer
S Marrache, JH Choi, S Tundup, D Zaver, DA Harn, S Dhar
Integrative biology 5 (1), 215-223, 2013
542013
Evaluation of nanoparticle delivered cisplatin in beagles
B Feldhaeusser, SR Platt, S Marrache, N Kolishetti, RK Pathak, ...
Nanoscale 7 (33), 13822-13830, 2015
442015
Nanocarriers for tracking and treating diseases
S Marrache, R Kumar Pathak, K L Darley, J H Choi, D Zaver, N Kolishetti, ...
Current medicinal chemistry 20 (28), 3500-3514, 2013
432013
Defective hCNT1 transport contributes to gemcitabine chemoresistance in ovarian cancer subtypes: overcoming transport defects using a nanoparticle approach
SW Hung, S Marrache, S Cummins, YD Bhutia, H Mody, SB Hooks, ...
Cancer letters 359 (2), 233-240, 2015
352015
Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies
SW Hung, H Mody, S Marrache, YD Bhutia, F Davis, JH Cho, J Zastre, ...
PloS one 8 (8), e71196, 2013
282013
Apoptosis-targeting nanoparticles
S Dhar, S Marrache
US Patent 9,901,616, 2018
172018
Immune-stimulating photoactive hybrid nanoparticles
S Dhar, J Choi, S Marrache
US Patent 9,517,277, 2016
162016
Formulation and optimization of mitochondria-targeted polymeric nanoparticles
S Marrache, RK Pathak, S Dhar
Mitochondrial Medicine: Volume II, Manipulating Mitochondrial Function, 103-112, 2015
152015
Ex vivo generation of functional immune cells by mitochondria-targeted photosensitization of cancer cells
S Marrache, S Tundup, DA Harn, S Dhar
Mitochondrial Medicine: Volume II, Manipulating Mitochondrial Function, 113-122, 2015
92015
Nanoparticles for mitochondrial trafficking of agents
S Dhar, SM Marrache
US Patent 10,416,167, 2019
82019
Mitochondrial delivery of 3-bromopyruvate
S Dhar, S Marrache
US Patent 10,398,663, 2019
82019
Core hydrophobicity tuning of a self-assembled particle results in efficient lipid reduction and favorable organ distribution
B Banik, R Wen, S Marrache, A Kumar, N Kolishetti, EW Howerth, S Dhar
Nanoscale 10 (1), 366-377, 2018
82018
Therapeutic nanoparticles for accumulation in the brain
S Dhar, EW Baker, S Marrache, FD West
US Patent App. 15/501,022, 2017
62017
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