Mario J Borgnia
Mario J Borgnia
Staff Scientist, National Institute of Environmental Health Sciences
Verified email at
Cited by
Cited by
Cellular and molecular biology of the aquaporin water channels
M Borgnia, S Nielsen, A Engel, P Agre
Annual review of biochemistry 68 (1), 425-458, 1999
Molecular architecture of native HIV-1 gp120 trimers
J Liu, A Bartesaghi, MJ Borgnia, G Sapiro, S Subramaniam
Nature 455 (7209), 109-113, 2008
The aquaporins, blueprints for cellular plumbing systems
P Agre, M Bonhivers, MJ Borgnia
Journal of Biological Chemistry 273 (24), 14659-14662, 1998
Functional reconstitution and characterization of AqpZ, the E. coli water channel protein
MJ Borgnia, D Kozono, G Calamita, PC Maloney, P Agre
Journal of molecular biology 291 (5), 1169-1179, 1999
Cryo‐electron microscopy–a primer for the non‐microscopist
JLS Milne, MJ Borgnia, A Bartesaghi, EEH Tran, LA Earl, DM Schauder, ...
The FEBS journal 280 (1), 28-45, 2013
Controlling the SARS-CoV-2 spike glycoprotein conformation
R Henderson, RJ Edwards, K Mansouri, K Janowska, V Stalls, ...
Nature structural & molecular biology 27 (10), 925-933, 2020
Structural mechanism of trimeric HIV-1 envelope glycoprotein activation
EEH Tran, MJ Borgnia, O Kuybeda, DM Schauder, A Bartesaghi, ...
PLoS pathogens 8 (7), e1002797, 2012
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli
MJ Borgnia, P Agre
Proceedings of the National Academy of Sciences 98 (5), 2888-2893, 2001
High resolution AFM topographs of the Escherichia coli water channel aquaporin Z
S Scheuring, P Ringler, M Borgnia, H Stahlberg, DJ Müller, P Agre, ...
The EMBO Journal 18 (18), 4981-4987, 1999
Molecular architectures of trimeric SIV and HIV-1 envelope glycoproteins on intact viruses: strain-dependent variation in quaternary structure
TA White, A Bartesaghi, MJ Borgnia, JR Meyerson, MJV De la Cruz, ...
PLoS pathogens 6 (12), e1001249, 2010
Trimeric HIV-1 glycoprotein gp140 immunogens and native HIV-1 envelope glycoproteins display the same closed and open quaternary molecular architectures
A Harris, MJ Borgnia, D Shi, A Bartesaghi, H He, R Pejchal, Y Kang, ...
Proceedings of the National Academy of Sciences 108 (28), 11440-11445, 2011
Prefusion structure of trimeric HIV-1 envelope glycoprotein determined by cryo-electron microscopy
A Bartesaghi, A Merk, MJ Borgnia, JLS Milne, S Subramaniam
Nature structural & molecular biology 20 (12), 1352-1357, 2013
Competition of Hydrophobic Peptides, Cytotoxic Drugs, and Chemosensitizers on a Common P-glycoprotein Pharmacophore as Revealed by Its ATPase Activity (∗)
MJ Borgnia, GD Eytan, YG Assaraf
Journal of Biological Chemistry 271 (6), 3163-3171, 1996
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel
Y Yin, SC Le, AL Hsu, MJ Borgnia, H Yang, SY Lee
Science 363 (6430), eaav9334, 2019
Highly selective water channel activity measured by voltage clamp: analysis of planar lipid bilayers reconstituted with purified AqpZ
P Pohl, SM Saparov, MJ Borgnia, P Agre
Proceedings of the National Academy of Sciences 98 (17), 9624-9629, 2001
Cryo-EM structures of the magnesium channel CorA reveal symmetry break upon gating
D Matthies, O Dalmas, MJ Borgnia, PK Dominik, A Merk, P Rao, ...
Cell 164 (4), 747-756, 2016
A core-weighted fitting method for docking atomic structures into low-resolution maps: application to cryo-electron microscopy
X Wu, JLS Milne, MJ Borgnia, AV Rostapshov, S Subramaniam, ...
Journal of structural biology 141 (1), 63-76, 2003
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation
KO Saunders, K Wiehe, M Tian, P Acharya, T Bradley, SM Alam, EP Go, ...
Science 366 (6470), eaay7199, 2019
Molecular structure of a 9-MDa icosahedral pyruvate dehydrogenase subcomplex containing the E2 and E3 enzymes using cryoelectron microscopy
JLS Milne, X Wu, MJ Borgnia, JS Lengyel, BR Brooks, D Shi, RN Perham, ...
Journal of Biological Chemistry 281 (7), 4364-4370, 2006
Structure of the water channel AqpZ from Escherichia coli revealed by electron crystallography
P Ringler, MJ Borgnia, H Stahlberg, PC Maloney, P Agre, A Engel
Journal of molecular biology 291 (5), 1181-1190, 1999
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