Ioannis Manolaridis
Ioannis Manolaridis
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Structure of the human multidrug transporter ABCG2
NMI Taylor, I Manolaridis, SM Jackson, J Kowal, H Stahlberg, KP Locher
Nature 546 (7659), 504-509, 2017
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2
SM Jackson, I Manolaridis, J Kowal, M Zechner, NMI Taylor, M Bause, ...
Nature structural & molecular biology 25 (4), 333-340, 2018
Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states
I Manolaridis, SM Jackson, NMI Taylor, J Kowal, H Stahlberg, KP Locher
Nature 563 (7731), 426-430, 2018
Mechanism of farnesylated CAAX protein processing by the intramembrane protease Rce1
I Manolaridis, K Kulkarni, RB Dodd, S Ogasawara, Z Zhang, G Bineva, ...
Nature 504 (7479), 301-305, 2013
Structure of the C-terminal domain of human La protein reveals a novel RNA recognition motif coupled to a helical nuclear retention element
A Jacks, J Babon, G Kelly, I Manolaridis, PD Cary, S Curry, MR Conte
Structure 11 (7), 833-843, 2003
Mechanism of isoprenylcysteine carboxyl methylation from the crystal structure of the integral membrane methyltransferase ICMT
J Yang, K Kulkarni, I Manolaridis, Z Zhang, RB Dodd, C Mas-Droux, ...
Molecular cell 44 (6), 997-1004, 2011
Papain-like protease 1 from transmissible gastroenteritis virus: crystal structure and enzymatic activity toward viral and cellular substrates
JA Wojdyla, I Manolaridis, PB van Kasteren, M Kikkert, EJ Snijder, ...
Journal of Virology 84 (19), 10063-10073, 2010
Structural basis of drug recognition by the multidrug transporter ABCG2
J Kowal, D Ni, SM Jackson, I Manolaridis, H Stahlberg, KP Locher
Journal of molecular biology 433 (13), 166980, 2021
Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism
Q Yu, D Ni, J Kowal, I Manolaridis, SM Jackson, H Stahlberg, KP Locher
Nature Communications 12 (1), 4376, 2021
Structure of the C-terminal domain of nsp4 from feline coronavirus
I Manolaridis, JA Wojdyla, S Panjikar, EJ Snijder, AE Gorbalenya, ...
Acta Crystallographica Section D: Biological Crystallography 65 (8), 839-846, 2009
Tariquidar-related triazoles as potent, selective and stable inhibitors of ABCG2 (BCRP)
F Antoni, M Bause, M Scholler, S Bauer, SA Stark, SM Jackson, ...
European journal of medicinal chemistry 191, 112133, 2020
Structure of the X (ADRP) domain of nsp3 from feline coronavirus
JA Wojdyla, I Manolaridis, EJ Snijder, AE Gorbalenya, B Coutard, ...
Acta Crystallographica Section D: Biological Crystallography 65 (12), 1292-1300, 2009
Structure and genetic analysis of the arterivirus nonstructural protein 7α
I Manolaridis, C Gaudin, CC Posthuma, JC Zevenhoven-Dobbe, I Imbert, ...
Journal of virology 85 (14), 7449-7453, 2011
Structural and biophysical characterization of the proteins interacting with the herpes simplex virus 1 origin of replication
I Manolaridis, E Mumtsidu, P Konarev, AM Makhov, SW Fullerton, A Sinz, ...
Journal of biological chemistry 284 (24), 16343-16353, 2009
Structural Basis of the Allosteric Inhibition of Human ABCG2 by Nanobodies
RN Irobalieva, I Manolaridis, SM Jackson, D Ni, E Pardon, H Stahlberg, ...
Journal of Molecular Biology 435 (19), 168234, 2023
Resonance assignment of nsp7α from arterivirus
C Gaudin, I Manolaridis, PA Tucker, MR Conte
Biomolecular NMR assignments 5, 23-25, 2011
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