Srinivas Gopala
Srinivas Gopala
Scientist G & Head, Department of Biochemistry, Sree Chitra Tirunal Institute for Medical Sciences
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Risk factor profile for chronic non-communicable diseases: results of a community-based study in Kerala, India
KR Thankappan, B Shah, P Mathur, PS Sarma, G Srinivas, GK Mini, ...
Indian J Med Res 131, 53-63, 2010
Allicin (from garlic) induces caspase-mediated apoptosis in cancer cells
S Oommen, RJ Anto, G Srinivas, D Karunagaran
European journal of pharmacology 485 (1-3), 97-103, 2004
Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent
G Srinivas, S Babykutty, PP Sathiadevan, P Srinivas
Medicinal research reviews 27 (5), 591-608, 2007
Emodin induces apoptosis of human cervical cancer cells through poly (ADP-ribose) polymerase cleavage and activation of caspase-9
G Srinivas, RJ Anto, P Srinivas, S Vidhyalakshmi, VP Senan, ...
European journal of pharmacology 473 (2-3), 117-125, 2003
Plumbagin induces reactive oxygen species, which mediate apoptosis in human cervical cancer cells
P Srinivas, G Gopinath, A Banerji, A Dinakar, G Srinivas
Molecular Carcinogenesis: Published in Cooperation with the University of …, 2004
Aloe emodin inhibits colon cancer cell migration/angiogenesis by downregulating MMP-2/9, RhoB and VEGF via reduced DNA binding activity of NF-κB
P Suboj, S Babykutty, DRV Gopi, RS Nair, P Srinivas, S Gopala
European journal of pharmaceutical sciences 45 (5), 581-591, 2012
Nimbolide retards tumor cell migration, invasion, and angiogenesis by downregulating MMP‐2/9 expression via inhibiting ERK1/2 and reducing DNA‐binding activity of NF‐κB in …
S Babykutty, P PS, N RJ, MAS Kumar, MS Nair, P Srinivas, S Gopala
Molecular carcinogenesis 51 (6), 475-490, 2012
Apoptosis induction of Centella asiatica on human breast cancer cells
S Babykutty, J Padikkala, P Sathiadevan, V Vijayakurup, T Azis, ...
African Journal of Traditional, Complementary and Alternative Medicines 6 (1), 2009
Insidious role of nitric oxide in migration/invasion of colon cancer cells by upregulating MMP-2/9 via activation of cGMP-PKG-ERK signaling pathways
S Babykutty, P Suboj, P Srinivas, AS Nair, K Chandramohan, S Gopala
Clinical & experimental metastasis 29, 471-492, 2012
Radiosensitizing effects of plumbagin in cervical cancer cells is through modulation of apoptotic pathway
S Nair, RRK Nair, P Srinivas, G Srinivas, MR Pillai
Molecular Carcinogenesis: Published in cooperation with the University of …, 2008
Estrogen-dependent cell signaling and apoptosis in BRCA1-blocked BG1 ovarian cancer cells in response to plumbagin and other chemotherapeutic agents
KA Thasni, S Rakesh, G Rojini, T Ratheeshkumar, G Srinivas, S Priya
Annals of oncology 19 (4), 696-705, 2008
Aloe emodin induces G2/M cell cycle arrest and apoptosis via activation of caspase-6 in human colon cancer cells
P Suboj, S Babykutty, P Srinivas, S Gopala
Pharmacology 89 (1-2), 91-98, 2012
Mutant p53 protein, Bcl-2/Bax ratios and apoptosis in paediatric acute lymphoblastic leukaemia
G Srinivas, P Kusumakumary, MK Nair, KR Panicker, MR Pillai
Journal of cancer research and clinical oncology 126, 62-67, 2000
Antisense blocking of BRCA1 enhances sensitivity to plumbagin but not tamoxifen in BG‐1 ovarian cancer cells
G Srinivas, LA Annab, G Gopinath, A Banerji, P Srinivas
Molecular Carcinogenesis: Published in cooperation with the University of …, 2004
‘How can I halt thee?’The puzzles involved in autophagic inhibition
V Vinod, CJ Padmakrishnan, B Vijayan, S Gopala
Pharmacological research 82, 1-8, 2014
Identification of de novo synthesized and relatively older proteins: accelerated oxidative damage to de novo synthesized apolipoprotein A-1 in type 1 diabetes
A Jaleel, GC Henderson, BJ Madden, KA Klaus, DM Morse, S Gopala, ...
Diabetes 59 (10), 2366-2374, 2010
Altered skeletal muscle mitochondrial proteome as the basis of disruption of mitochondrial function in diabetic mice
P Zabielski, IR Lanza, S Gopala, CJ Holtz Heppelmann, HR Bergen III, ...
Diabetes 65 (3), 561-573, 2016
Genistein induces apoptosis in ovarian cancer cells via different molecular pathways depending on Breast Cancer Susceptibility gene-1 (BRCA1) status
KAA Thasni, G Rojini, SN Rakesh, T Ratheeshkumar, MS Babu, ...
European journal of pharmacology 588 (2-3), 158-164, 2008
High LC3/Beclin expression correlates with poor survival in glioma: a definitive role for autophagy as evidenced by in vitro autophagic flux
P Cj, E Hv, V Vijayakurup, G R Menon, S Nair, S Gopala
Pathology & Oncology Research 25, 137-148, 2019
Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes
GN Ruegsegger, S Manjunatha, P Summer, S Gopala, P Zabeilski, ...
The FASEB Journal 33 (3), 4458, 2019
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