Bruce Xue Wen Wong
Bruce Xue Wen Wong
Research Associate, University of Cambridge, ARUK Drug Discovery Institute
Verified email at medschl.cam.ac.uk
Title
Cited by
Cited by
Year
Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
P Lei, S Ayton, DI Finkelstein, L Spoerri, GD Ciccotosto, DK Wright, ...
Nature medicine 18 (2), 291, 2012
3732012
Ceruloplasmin dysfunction and therapeutic potential for Parkinson disease
S Ayton, P Lei, JA Duce, BXW Wong, A Sedjahtera, PA Adlard, AI Bush, ...
Annals of neurology 73 (4), 554-559, 2013
1542013
β-Amyloid precursor protein does not possess ferroxidase activity but does stabilize the cell surface ferrous iron exporter ferroportin
BX Wong, A Tsatsanis, LQ Lim, PA Adlard, AI Bush, JA Duce
PLoS One 9 (12), 2014
902014
Amyloid-β peptide Aβ3pE-42 induces lipid peroxidation, membrane permeabilization, and calcium influx in neurons
AP Gunn, BX Wong, T Johanssen, JC Griffith, CL Masters, AI Bush, ...
Journal of Biological Chemistry 291 (12), 6134-6145, 2016
432016
The iron regulatory capability of the major protein participants in prevalent neurodegenerative disorders
BX Wong, JA Duce
Frontiers in pharmacology 5, 81, 2014
412014
Metals and cholesterol: two sides of the same coin in Alzheimer’s disease pathology
BX Wong, YH Hung, AI Bush, JA Duce
Frontiers in aging neuroscience 6, 91, 2014
372014
Post translational changes to α-synuclein control iron and dopamine trafficking; a concept for neuron vulnerability in Parkinson’s disease
JA Duce, BX Wong, H Durham, JC Devedjian, DP Smith, D Devos
Molecular neurodegeneration 12 (1), 45, 2017
352017
P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in …
BJ Gu, JA Duce, VA Valova, B Wong, AI Bush, S Petrou, JS Wiley
Journal of Biological Chemistry 287 (21), 17318-17330, 2012
212012
A comparison of ceruloplasmin to biological polyanions in promoting the oxidation of Fe2+ under physiologically relevant conditions
BX Wong, S Ayton, LQ Lam, P Lei, PA Adlard, AI Bush, JA Duce
Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (12), 3299-3310, 2014
202014
Marked age-related changes in brain iron homeostasis in amyloid protein precursor knockout mice
AA Belaidi, AP Gunn, BX Wong, S Ayton, AT Appukuttan, BR Roberts, ...
Neurotherapeutics 15 (4), 1055-1062, 2018
132018
Modulation of macrophage fatty acid content and composition by exposure to dyslipidemic serum in vitro
BXW Wong, RA Kyle, KD Croft, CM Quinn, W Jessup, BB Yeap
Lipids 46 (4), 371-380, 2011
122011
Dyslipidemic diabetic serum increases lipid accumulation and expression of stearoyl-CoA desaturase in human macrophages
BXW Wong, RA Kyle, PC Myhill, KD Croft, CM Quinn, W Jessup, BB Yeap
Lipids 46 (10), 931-941, 2011
112011
Amyloid precursor protein drives down-regulation of mitochondrial oxidative phosphorylation independent of amyloid beta
MIGL Sanchez, HS Waugh, A Tsatsanis, BX Wong, JG Crowston, JA Duce, ...
Scientific reports 7 (1), 1-10, 2017
92017
Post Translational Modulation of β-Amyloid Precursor Protein Trafficking to the Cell Surface Alters Neuronal Iron Homeostasis
A Tsatsanis, S Dickens, JCF Kwok, BX Wong, JA Duce
Neurochemical research 44 (6), 1367-1374, 2019
52019
Oxidation of iron under physiologically relevant conditions in biological fluids from healthy and Alzheimer’s disease subjects
LQ Lam, BX Wong, T Frugier, QX Li, SJ Collins, AI Bush, PJ Crack, ...
ACS chemical neuroscience 8 (4), 731-736, 2017
22017
Amyloidogenic processing of beta-amyloid precursor protein promotes ferroptosis: implications for Alzheimer's disease
J Duce, B Wong, A Tsatsanis, A Gunn, L Lam, S Ayton, D Devos, A Bush
JOURNAL OF NEUROCHEMISTRY 142, 156-156, 2017
2017
Innate immune response protein lactoferrin directly binds amyloid-beta precursor protein to promote amyloidogenic processing
A Tsatsanis, T Ryan, B Wong, R Evans, A Bush, J Duce
JOURNAL OF NEUROCHEMISTRY 142, 66-66, 2017
2017
Oxidation of iron under physiologically relevant conditions in biological fluids from healthy and Alzheimer’s disease
LQ Lam, BX Wong, T Frugier, QX Li, SJ Collins, AI Bush, PJ Crack, ...
2017
Evaluating Iron Flux in the Brain
BX Wong, LQ Lam, A Tsatsanis, JA Duce
Metals in the Brain, 161-193, 2017
2017
The influence of amyloid-β precursor protein proteolytic processing on neuronal iron homeostasis: WTH12-07
J Duce, B Wong, A Tsatsanis, L Lam, S Ayton, P Adlard, A Bush
Journal of Neurochemistry 134, 2015
2015
The system can't perform the operation now. Try again later.
Articles 1–20