| The role of tumour–stromal interactions in modifying drug response: challenges and opportunities DW McMillin, JM Negri, CS Mitsiades Nature reviews Drug discovery 12 (3), 217-228, 2013 | 503 | 2013 |
| Tumor cell-specific bioluminescence platform to identify stroma-induced changes to anticancer drug activity DW McMillin, J Delmore, E Weisberg, JM Negri, DC Geer, S Klippel, ... Nature medicine 16 (4), 483-489, 2010 | 372 | 2010 |
| Antitumor Effects of the Proteasome Inhibitor Bortezomib in Medullary and Anaplastic Thyroid Carcinoma Cells in Vitro CS Mitsiades, D McMillin, V Kotoula, V Poulaki, C McMullan, J Negri, ... The Journal of Clinical Endocrinology & Metabolism 91 (10), 4013-4021, 2006 | 158 | 2006 |
| Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 DW McMillin, M Ooi, J Delmore, J Negri, P Hayden, N Mitsiades, ... Cancer research 69 (14), 5835-5842, 2009 | 154 | 2009 |
| Niche-based screening identifies small-molecule inhibitors of leukemia stem cells KA Hartwell, PG Miller, S Mukherjee, AR Kahn, AL Stewart, DJ Logan, ... Nature chemical biology 9 (12), 840-848, 2013 | 133 | 2013 |
| Novel histone deacetylase inhibitors in the treatment of thyroid cancer CS Mitsiades, V Poulaki, C McMullan, J Negri, G Fanourakis, ... Clinical Cancer Research 11 (10), 3958-3965, 2005 | 117 | 2005 |
| Anti-tumor activity and signaling events triggered by the isothiocyanates, sulforaphane and phenethyl isothiocyanate, in multiple myeloma J Jakubikova, D Cervi, M Ooi, K Kim, S Nahar, S Klippel, D Cholujova, ... Haematologica 96 (8), 1170, 2011 | 92 | 2011 |
| Cell-type dependent Alzheimer's disease phenotypes: probing the biology of selective neuronal vulnerability CR Muratore, C Zhou, M Liao, MA Fernandez, WM Taylor, ... Stem cell reports 9 (6), 1868-1884, 2017 | 82 | 2017 |
| Epidermal growth factor receptor as a therapeutic target in human thyroid carcinoma: mutational and functional analysis CS Mitsiades, V Kotoula, V Poulaki, E Sozopoulos, J Negri, ... The Journal of Clinical Endocrinology & Metabolism 91 (9), 3662-3666, 2006 | 78 | 2006 |
| Cell models of lipid-rich α-synuclein aggregation validate known modifiers of α-synuclein biology and identify stearoyl-CoA desaturase T Imberdis, J Negri, N Ramalingam, E Terry-Kantor, GPH Ho, S Fanning, ... Proceedings of the National Academy of Sciences 116 (41), 20760-20769, 2019 | 74 | 2019 |
| Targeting BRAFV600E in thyroid carcinoma: therapeutic implications CS Mitsiades, J Negri, C McMullan, DW McMillin, E Sozopoulos, ... Molecular cancer therapeutics 6 (3), 1070-1078, 2007 | 73 | 2007 |
| A chemical screen probing the relationship between mitochondrial content and cell size T Kitami, DJ Logan, J Negri, T Hasaka, NJ Tolliday, AE Carpenter, ... PloS one 7 (3), e33755, 2012 | 65 | 2012 |
| Discovery of 1, 3-diaminobenzenes as selective inhibitors of platelet activation at the PAR1 receptor C Dockendorff, O Aisiku, L VerPlank, JR Dilks, DA Smith, SF Gunnink, ... ACS Medicinal Chemistry Letters 3 (3), 232-237, 2012 | 59 | 2012 |
| Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing V Poulaki, CS Mitsiades, C McMullan, G Fanourakis, J Negri, ... Investigative ophthalmology & visual science 46 (1), 358-366, 2005 | 59 | 2005 |
| The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro V Poulaki, CS Mitsiades, V Kotoula, J Negri, D McMillin, JW Miller, ... Investigative ophthalmology & visual science 48 (10), 4706-4719, 2007 | 58 | 2007 |
| Assessment of spontaneous neuronal activity in vitro using multi-well multi-electrode arrays: implications for assay development J Negri, V Menon, TL Young-Pearse ENeuro 7 (1), 2020 | 41 | 2020 |
| Compartment-Specific Bioluminescence Imaging platform for the high-throughput evaluation of antitumor immune function DW McMillin, J Delmore, JM Negri, M Vanneman, S Koyama, ... Blood, The Journal of the American Society of Hematology 119 (15), e131-e138, 2012 | 41 | 2012 |
| Microenvironmental influence on pre-clinical activity of polo-like kinase inhibition in multiple myeloma: implications for clinical translation DW McMillin, J Delmore, J Negri, M Ooi, S Klippel, CV Miduturu, NS Gray, ... PloS one 6 (7), e20226, 2011 | 35 | 2011 |
| Bcl-2 overexpression in thyroid carcinoma cells increases sensitivity to Bcl-2 homology 3 domain inhibition CS Mitsiades, P Hayden, V Kotoula, DW McMillin, C McMullan, J Negri, ... The Journal of Clinical Endocrinology & Metabolism 92 (12), 4845-4852, 2007 | 34 | 2007 |
| Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression MM Nagiec, AP Skepner, J Negri, M Eichhorn, N Kuperwasser, E Comer, ... PLoS One 10 (3), e0120295, 2015 | 30 | 2015 |
