Polly Leilei Chen
Polly Leilei Chen
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Recoding RNA editing of AZIN1 predisposes to hepatocellular carcinoma
L Chen, Y Li, CH Lin, THM Chan, RKK Chow, Y Song, M Liu, YF Yuan, ...
Nature medicine 19 (2), 209-216, 2013
MicroRNA-375 inhibits tumour growth and metastasis in oesophageal squamous cell carcinoma through repressing insulin-like growth factor 1 receptor
KL Kong, DLW Kwong, THM Chan, SYK Law, L Chen, Y Li, YR Qin, ...
Gut 61 (1), 33-42, 2012
Interleukin 17A promotes hepatocellular carcinoma metastasis via NF-kB induced matrix metalloproteinases 2 and 9 expression
J Li, GKK Lau, L Chen, S Dong, HY Lan, XR Huang, Y Li, JM Luk, ...
PloS one 6 (7), e21816, 2011
A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma
THM Chan, CH Lin, L Qi, J Fei, Y Li, KJ Yong, M Liu, Y Song, RKK Chow, ...
Gut 63 (5), 832-843, 2014
Overexpression of eukaryotic initiation factor 5A2 enhances cell motility and promotes tumor metastasis in hepatocellular carcinoma
DJ Tang, SS Dong, NF Ma, D Xie, L Chen, L Fu, SH Lau, Y Li, Y Li, ...
Hepatology 51 (4), 1255-1263, 2010
Adenosine-to-inosine RNA editing mediated by ADARs in esophageal squamous cell carcinoma
YR Qin, JJ Qiao, THM Chan, YH Zhu, FF Li, H Liu, J Fei, Y Li, XY Guan, ...
Cancer research 74 (3), 840-851, 2014
CHD1L promotes hepatocellular carcinoma progression and metastasis in mice and is associated with these processes in human patients
L Chen, THM Chan, YF Yuan, L Hu, J Huang, S Ma, J Wang, SS Dong, ...
The Journal of clinical investigation 120 (4), 1178-1191, 2010
Isolation and characterization of a novel oncogene, amplified in liver cancer 1, within a commonly amplified region at 1q21 in hepatocellular carcinoma
NF Ma, L Hu, JM Fung, D Xie, BJ Zheng, L Chen, DJ Tang, L Fu, Z Wu, ...
Hepatology 47 (2), 503-510, 2008
ADAR-mediated RNA editing predicts progression and prognosis of Gastric Cancer
Gastroenterology, 2016
Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial‐mesenchymal transition by way of Akt/GSK‐3β/Snail signaling
L Liu, Y Dai, J Chen, T Zeng, Y Li, L Chen, YH Zhu, J Li, Y Li, S Ma, D Xie, ...
Hepatology 59 (2), 531-543, 2014
Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non‐small cell lung cancer
A Ali, E Levantini, JT Teo, J Goggi, JG Clohessy, CS Wu, L Chen, H Yang, ...
EMBO molecular medicine 10 (3), e8313, 2018
SPOCK1 is regulated by CHD1L and blocks apoptosis and promotes HCC cell invasiveness and metastasis in mice
Y Li, L Chen, THM Chan, M Liu, KL Kong, JL Qiu, YF Yuan, XY Guan
Gastroenterology 144 (1), 179-191. e4, 2013
Overexpression of cathepsin Z contributes to tumor metastasis by inducing epithelial-mesenchymal transition in hepatocellular carcinoma
J Wang, L Chen, Y Li, XY Guan
PloS one 6 (9), e24967, 2011
Characterization of Tumor-Suppressive Function of SOX6 in Human Esophageal Squamous Cell Carcinoma
YR Qin, H Tang, F Xie, H Liu, Y Zhu, J Ai, L Chen, Y Li, DL Kwong, L Fu, ...
Clinical cancer research 17 (1), 46-55, 2011
RNA editome imbalance in hepatocellular carcinoma
L Qi, THM Chan, DG Tenen, L Chen
Cancer research 74 (5), 1301-1306, 2014
Interleukin 23 promotes hepatocellular carcinoma metastasis via NF-kappa B induced matrix metalloproteinase 9 expression
J Li, G Lau, L Chen, YF Yuan, J Huang, JM Luk, D Xie, XY Guan
Public Library of Science 7 (9), e46264, 2012
Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis
PJ Teoh, O An, TH Chung, JY Chooi, SHM Toh, S Fan, W Wang, BTH Koh, ...
Blood, The Journal of the American Society of Hematology 132 (12), 1304-1317, 2018
Translationally controlled tumor protein induces mitotic defects and chromosome missegregation in hepatocellular carcinoma development
THM Chan, L Chen, M Liu, L Hu, B Zheng, VKM Poon, P Huang, YF Yuan, ...
Hepatology 55 (2), 491-505, 2012
AZIN1 RNA editing confers cancer stemness and enhances oncogenic potential in colorectal cancer
K Shigeyasu, Y Okugawa, S Toden, J Miyoshi, Y Toiyama, T Nagasaka, ...
JCI insight 3 (12), 2018
Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development
SJ Tang, H Shen, O An, HQ Hong, J Li, Y Song, J Han, DJT Tay, VHE Ng, ...
Nature communications 11 (1), 799, 2020
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